| General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information | |
|---|---|
Gene ID | 2778 |
Name | GNAS |
Synonymous | AHO|C20orf45|GNAS1|GPSA|GSA|GSP|NESP|PHP1A|PHP1B|PHP1C|POH;GNAS complex locus;GNAS;GNAS complex locus |
Definition | adenylate cyclase-stimulating G alpha protein|alternative gene product encoded by XL-exon|extra large alphas protein|guanine nucleotide binding protein (G protein), alpha stimulating activity polypeptide 1|guanine nucleotide regulatory protein|guanine nuc |
Position | 20q13.3 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | G-alpha-s(h) + Fascin(h) <==> G-alpha-s(h):Fascin(h) (binding) | G-alpha-s(h) + acetyl-CoA acetyltransferase, cytosolic(h) <==> G-alpha-s(h):acetyl-CoA acetyltransferase, cytosolic(h) (binding) | G-alpha-s(h) + multifunctional protein ADE2(h) <==> G-alpha-s(h):multifunctional protein ADE2(h) (binding) | G-alpha-s(h) + Pontin52(h) <==> G-alpha-s(h):Pontin52(h) (binding) | G-alpha-s(h) + shmt2(h) <==> G-alpha-s(h):shmt2(h) (binding) | G-alpha-s(h) + GTP <==> G-alpha-s(h):GTP (binding) | mc1r(m.s.) + G-alpha-s(h) <==> mc1r(m.s.):G-alpha-s(h) (binding) | GNAS(h) --> G-alpha-s(h) (expression). | G-alpha-s2(h) + calmodulin(b) <==> G-alpha-s2(h):calmodulin(b) (binding) | GNAS(h) --> G-alpha-s2(h) (expression). | GNAS(h) --> G-alpha-s1(h) (expression). | GNAS(h) --> Nesp55(h) (expression). | GNAS(h) --> XLas-1(h) (expression). | GNAS(h) --> XLas-2(h) (expression). | GNAS(h) --> XLas-3(h) (expression). | GNAS(h) --> ALEX(h) (expression). |
|---|
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 694 | Phosphoserine (By similarity). | Swiss-Prot 53.0 | 844 | ADP-ribosylarginine; by cholera toxin (Bysimilarity). | Swiss-Prot 53.0 | 2 | N-palmitoyl glycine (By similarity). | Swiss-Prot 53.0 | 3 | S-palmitoyl cysteine (By similarity). | Swiss-Prot 53.0 | 51 | Phosphoserine (By similarity). | Swiss-Prot 53.0 | 201 | ADP-ribosylarginine; by cholera toxin (Bysimilarity). | Swiss-Prot 53.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr20 |
Promoter: 56898321 - 56900321 | Agilent_014791 |
chr20 |
Promoter: 56846690 - 56848690 | Agilent_014791 |
chr20 |
Promoter: 56859931 - 56861931 | Agilent_014791 |
chr20 |
Promoter: 56846690 - 56848690 | GoldenGate_Methylation_Cancer_Panel_I |
chr20 |
Promoter: 56898321 - 56900321 | GSE27584 |
chr20 |
Promoter: 56846690 - 56848690 | GSE27584 |
chr20 |
Promoter: 56898321 - 56900321 | GSE27584 |
chr20 |
Promoter: 56859931 - 56861931 | GSE27584 |
chr20 |
Promoter: 56859931 - 56861931 | GSE27584 |
chr20 |
Promoter: 56898320 - 56900320 | GSE27584 |
chr20 |
Promoter: 56898664 - 56900664 | GSE27584 |
chr20 |
Promoter: 56846690 - 56848690 | Agilent_014791_44K |
chr20 |
Promoter: 56898321 - 56900321 | E-GEOD-20553 |
chr20 |
Promoter: 56898664 - 56900664 | E-GEOD-20553 |
chr20 |
Promoter: 56898320 - 56900320 | E-GEOD-20553 |
chr20 |
Promoter: 56859931 - 56861931 | E-GEOD-20553 |
chr20 |
Promoter: 56846690 - 56848690 | E-GEOD-20553 |
chr20 |
Promoter: 56859931 - 56861931 | E-GEOD-20553 |
chr20 |
Promoter: 56898321 - 56900321 | E-GEOD-20553 |