Pediatric cancer gene database (Pedican) Home
Pedican
Pediatric cancer database
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

2674

Name

GFRA1

Synonymous

GDNFR|GDNFRA|GFR-ALPHA-1|RET1L|RETL1|TRNR1;GDNF family receptor alpha 1;GFRA1;GDNF family receptor alpha 1

Definition

GDNF family receptor alpha-1|GDNF receptor alpha-1|GDNFR-alpha-1|GPI-linked anchor protein|Glial cell line-derived neurotrophic factor receptor alpha|PI-linked cell-surface accessory protein|RET ligand 1|TGF-beta related neurotrophic factor receptor 1|TGF

Position

10q26.11

Gene Type

protein-coding

Gene Regulation:

Transcription Factors
Post Translational Modification From dbPTM
Methylation Profile From DiseaseMeth database

Transcription Factors   [Top]

Regulation From TransFac database

GFRA1(h) --> GFR-alpha-1(h) (expression).
GFRA1(h) --> GFR-alpha-1-isoform1(h) (expression).
GFRA1(h) --> GFR-alpha-1-isoform2(h) (expression).

Post Translational Modification   [Top]

Location (AA)

PTM type

Literature

Database

59N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
347N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
406N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
429GPI-anchor amidated serine (Potential).Swiss-Prot 53.0

Methylation Profile   [Top]

Chromosome

Location

Source

chr10

Promoter: 118021284 - 118023284Agilent_014791

chr10

Promoter: 118022466 - 118024466GSE27584

chr10

Promoter: 118021284 - 118023284GSE27584


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