Pediatric cancer gene database (Pedican) Home
Pedican
Pediatric cancer database
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

2324

Name

FLT4

Synonymous

FLT41|LMPH1A|PCL|VEGFR3;fms-related tyrosine kinase 4;FLT4;fms-related tyrosine kinase 4

Definition

FLT-4|VEGFR-3|fms-like tyrosine kinase 4|soluble VEGFR3 variant 1|soluble VEGFR3 variant 2|soluble VEGFR3 variant 3|tyrosine-protein kinase receptor FLT4|vascular endothelial growth factor receptor 3

Position

5q35.3

Gene Type

protein-coding

Gene Regulation:

Transcription Factors
Post Translational Modification From dbPTM
Methylation Profile From DiseaseMeth database

Transcription Factors   [Top]

Regulation From TransFac database

VRP(h) + VEGFR-3(h) <==> VRP(h):VEGFR-3(h) (binding)
FLT4(h) --> VEGFR-3(h) (expression).

Post Translational Modification   [Top]

Location (AA)

PTM type

Literature

Database

33N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
104N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
166N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
251N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
299N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
411N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
515N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
527N-linked (GlcNAc...).Swiss-Prot 53.0
594N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
683N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
690N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
758N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1068Phosphotyrosine (by autocatalysis) (Bysimilarity).Swiss-Prot 53.0

Methylation Profile   [Top]

Chromosome

Location

Source

chr5

Promoter: 180008706 - 180010706Agilent_014791

chr5

Promoter: 180008706 - 180010706GoldenGate_Methylation_Cancer_Panel_I

chr5

Promoter: 180008706 - 180010706GoldenGate_Methylation_Cancer_Panel_I

chr5

Promoter: 180008706 - 180010706GSE27584

chr5

Promoter: 180008706 - 180010706GSE27584

chr5

Promoter: 180008706 - 180010706Agilent_014791_44K


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