Pediatric cancer gene database (Pedican) Home
Pedican
Pediatric cancer database
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

2264

Name

FGFR4

Synonymous

CD334|JTK2|TKF;fibroblast growth factor receptor 4;FGFR4;fibroblast growth factor receptor 4

Definition

FGFR-4|hydroxyaryl-protein kinase|protein-tyrosine kinase|tyrosine kinase related to fibroblast growth factor receptor|tyrosylprotein kinase

Position

5q35.1-qter

Gene Type

protein-coding

Gene Regulation:

Transcription Factors
Post Translational Modification From dbPTM
Methylation Profile From DiseaseMeth database

Transcription Factors   [Top]

Regulation From TransFac database

FGF-19(h) + fgfr4(h) <==> FGF-19(h):fgfr4(h) (binding)
FGFR4(h) --> fgfr4(h) (expression).
FGFR4(h) --> fgfr4(h) (expression).

Post Translational Modification   [Top]

Location (AA)

PTM type

Literature

Database

112N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
258N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
290N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
311N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
322N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
643Phosphotyrosine (by autocatalysis) (Bysimilarity).Swiss-Prot 53.0
754Phosphotyrosine (FGFR4)N.N.;8576110Phospho.ELM 6.0

Methylation Profile   [Top]

Chromosome

Location

Source

chr5

Promoter: 176447657 - 176449657Agilent_014791

chr5

Promoter: 176445027 - 176447027GoldenGate_Methylation_Cancer_Panel_I

chr5

Promoter: 176445027 - 176447027GoldenGate_Methylation_Cancer_Panel_I

chr5

Promoter: 176445027 - 176447027GSE27584

chr5

Promoter: 176445027 - 176447027GSE27584


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