| General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information | |
|---|---|
Gene ID | 2263 |
Name | FGFR2 |
Synonymous | BEK|BFR-1|CD332|CEK3|CFD1|ECT1|JWS|K-SAM|KGFR|TK14|TK25;fibroblast growth factor receptor 2;FGFR2;fibroblast growth factor receptor 2 |
Definition | BEK fibroblast growth factor receptor|FGF receptor|FGFR-2|bacteria-expressed kinase|hydroxyaryl-protein kinase|keratinocyte growth factor receptor|protein tyrosine kinase, receptor like 14|soluble FGFR4 variant 4 |
Position | 10q26 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | FGFR-2(h) + ATP --> FGFR-2(h){pY} + ADP (phosphorylation) | FGFR2(h) --> FGFR-2(h) (expression). | Spred-2(m) --/ FGFR-2(h) (decrease of abundance) | FGFR-2(h) + ATP --> FGFR-2(h){pY} + ADP (phosphorylation) | FGFR-2(h) + ubiquitin(h) --> FGFR-2(h){ub} (ubiquitination) | FGFR2(h) --> FGFR-2(h) (expression). |
|---|
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 83 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 123 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 228 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 241 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 265 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 297 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 318 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 331 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 657 | Phosphotyrosine (by autocatalysis) (Bysimilarity). | Swiss-Prot 53.0 | 769 | Phosphotyrosine | N.N. | Phospho.ELM 6.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr10 |
Promoter: 123348151 - 123348195 | Agilent_014791 |
chr10 |
Promoter: 123347462 - 123349462 | GoldenGate_Methylation_Cancer_Panel_I |
chr10 |
Promoter: 123347462 - 123349462 | GoldenGate_Methylation_Cancer_Panel_I |
chr10 |
Promoter: 123347462 - 123349462 | GSE27584 |
chr10 |
Promoter: 123347462 - 123349462 | GSE27584 |
chr10 |
Promoter: 123347462 - 123349462 | Agilent_014791_44K |