Entrez Gene

Basic Information
Gene ID	2260
Name	FGFR1
Synonymous	BFGFR\|CD331\|CEK\|FGFBR\|FGFR-1\|FLG\|FLT-2\|FLT2\|HBGFR\|KAL2\|N-SAM\|OGD\|bFGF-R-1;fibroblast growth factor receptor 1;FGFR1;fibroblast growth factor receptor 1
Definition	FGFR1/PLAG1 fusion\|FMS-like tyrosine kinase 2\|basic fibroblast growth factor receptor 1\|fms-related tyrosine kinase 2\|heparin-binding growth factor receptor\|hydroxyaryl-protein kinase\|proto-oncogene c-Fgr
Position	8p12
Gene Type	protein-coding
Gene Regulation:	Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database

Regulation From TransFac database
Transcription Factors [Top]
fgfr1(h) + ubiquitin(h) --c-Cbl(h)--> fgfr1(h){ub} (ubiquitination)
FGFR1(h) --> fgfr1(h) (expression).
FGFR1(h) --> fgfr1-isoform1(h) (expression).
FGFR1(h) --> fgfr1-isoform2(h) (expression).
FGFR1(h) --> fgfr1-isoform3(h) (expression).
FGFR1(h) --> fgfr1-isoform4(h) (expression).
FGFR1(h) --> fgfr1-isoform5(h) (expression).
FGFR1(h) --> fgfr1-isoform7(h) (expression).
FGFR1(h) --> fgfr1-isoform8(h) (expression).
FGFR1(h) --> fgfr1-isoform9(h) (expression).
FGFR1(h) --> fgfr1-isoform10(h) (expression).
FGFR1(h) --> fgfr1-isoform11(h) (expression).
FGFR1(h) --> fgfr1-isoform12(h) (expression).
FGFR1(h) --> fgfr1-isoform13(h) (expression).
FGFR1(h) --> fgfr1-isoform14(h) (expression).
FGFR1(h) --> fgfr1-isoform15(h) (expression).
FGFR1(h) --> fgfr1-isoform16(h) (expression).
FGFR1(h) --> fgfr1-isoform17(h) (expression).
FGFR1(h) --> fgfr1-isoform18(h) (expression).
FGFR1(h) --> fgfr1-isoform6(h) (expression).
FGFR1(h) --> fgfr1-isoform19(h) (expression).

Location (AA)	PTM type	Literature	Database
Post Translational Modification [Top]
77	N-linked (GlcNAc...) (Potential).		Swiss-Prot 53.0
117	N-linked (GlcNAc...) (Potential).		Swiss-Prot 53.0
227	N-linked (GlcNAc...) (Potential).		Swiss-Prot 53.0
240	N-linked (GlcNAc...) (Potential).		Swiss-Prot 53.0
264	N-linked (GlcNAc...) (Potential).		Swiss-Prot 53.0
296	N-linked (GlcNAc...).		Swiss-Prot 53.0
317	N-linked (GlcNAc...) (Potential).		Swiss-Prot 53.0
330	N-linked (GlcNAc...) (Potential).		Swiss-Prot 53.0
654	Phosphotyrosine (by autocatalysis) (Bysimilarity).		Swiss-Prot 53.0
766	Phosphotyrosine (by autocatalysis).		Swiss-Prot 53.0
463	Phosphotyrosine (FGFR1)	9880324;8622701;12601080	Phospho.ELM 6.0
766	Phosphotyrosine (FGFR1)	9880324;8622701	Phospho.ELM 6.0
154	Phosphotyrosine (FGFR1)	12601080	Phospho.ELM 6.0
583	Phosphotyrosine (FGFR1)	9880324;8622701;12601080	Phospho.ELM 6.0
585	Phosphotyrosine (FGFR1)	9880324;8622701;12601080	Phospho.ELM 6.0
653	Phosphotyrosine (FGFR1)	9880324;8622701;12601080	Phospho.ELM 6.0
654	Phosphotyrosine (FGFR1)	9880324;8622701;12601080	Phospho.ELM 6.0
730	Phosphotyrosine (FGFR1)	9880324;8622701;12601080	Phospho.ELM 6.0
280	Phosphotyrosine (FGFR1)	12601080	Phospho.ELM 6.0
307	Phosphotyrosine (FGFR1)	12601080	Phospho.ELM 6.0
605	Phosphotyrosine (FGFR1)	12601080	Phospho.ELM 6.0

Chromosome	Location	Source
Methylation Profile [Top]
chr8	Promoter: 38445009 - 38447009	Agilent_014791
chr8	Promoter: 38445009 - 38447009	GoldenGate_Methylation_Cancer_Panel_I
chr8	Promoter: 38445009 - 38447009	GoldenGate_Methylation_Cancer_Panel_I
chr8	Promoter: 38445009 - 38447009	GoldenGate_Methylation_Cancer_Panel_I
chr8	Promoter: 38445009 - 38447009	GoldenGate_Methylation_Cancer_Panel_I
chr8	Promoter: 38445009 - 38447009	GoldenGate_Methylation_Cancer_Panel_I
chr8	Promoter: 38445009 - 38447009	GoldenGate_Methylation_Cancer_Panel_I
chr8	Promoter: 38445009 - 38447009	GoldenGate_Methylation_Cancer_Panel_I
chr8	Promoter: 38445009 - 38447009	GSE27584
chr8	Promoter: 38445009 - 38447009	GSE27584
chr8	Promoter: 38445009 - 38447009	GSE27584
chr8	Promoter: 38445009 - 38447009	GSE27584
chr8	Promoter: 38445009 - 38447009	GSE27584
chr8	Promoter: 38445009 - 38447009	GSE27584
chr8	Promoter: 38445009 - 38447009	GSE27584
chr8	Promoter: 38445009 - 38447009	Agilent_014791_44K

Transcription Factors [Top]