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Pedican
Pediatric cancer database
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

1641

Name

DCX

Synonymous

DBCN|DC|LISX|SCLH|XLIS;doublecortin;DCX;doublecortin

Definition

doublecortex|doublin|lis-X|lissencephalin-X|neuronal migration protein doublecortin

Position

Xq22.3-q23

Gene Type

protein-coding

Gene Regulation:

Transcription Factors
Post Translational Modification From dbPTM
Methylation Profile From DiseaseMeth database

Transcription Factors   [Top]

Regulation From TransFac database

doublecortin(h) + ATP --JNK2(m){p}--> doublecortin(h){p} + ADP (phosphorylation)
doublecortin(h) + 3 NTP --JNK(v.s.)--> doublecortin(h){pT321}{pT331}{pS334} + 3 NDP (phosphorylation)
JNK2(m) + doublecortin(h) <==> JNK2(m):doublecortin(h) (binding)
JNK1(m) + doublecortin(h) <==> JNK1(m):doublecortin(h) (binding)
JIP1(h) + doublecortin(h) <==> JIP1(h):doublecortin(h) (binding)
DCX(h) --> doublecortin(h) (expression).
DCX(h) --> doublecortin-LIS-XA(h) (expression).
DCX(h) --> doublecortin-LIS-XB(h) (expression).
DCX(h) --> doublecortin-LIS-XC(h) (expression).
DCX(h) --> doublecortin-LIS-XD(h) (expression).

Post Translational Modification   [Top]

Location (AA)

PTM type

Literature

Database

56Phosphothreonine (by PKC) (Potential).Swiss-Prot 53.0
112Phosphotyrosine (by ABL) (Potential).Swiss-Prot 53.0
116Phosphoserine (by PKC) (Potential).Swiss-Prot 53.0
132Phosphoserine (by CK2) (Potential).Swiss-Prot 53.0
152Phosphoserine (by PKC) (Potential).Swiss-Prot 53.0
157Phosphoserine (by CK2) (Potential).Swiss-Prot 53.0
307Phosphoserine (by CK2) (Potential).Swiss-Prot 53.0
336Phosphoserine (by PKC) (Potential).Swiss-Prot 53.0
346Phosphoserine (By similarity).Swiss-Prot 53.0
348Phosphoserine (by CK2) (Potential).Swiss-Prot 53.0
359Phosphoserine (By similarity).Swiss-Prot 53.0
363Phosphothreonine (by PKC and MAPK)(Potential).Swiss-Prot 53.0
369Phosphoserine (by MAPK) (Potential).Swiss-Prot 53.0
372Phosphoserine.Swiss-Prot 53.0
373Phosphothreonine (by MAPK) (Potential).Swiss-Prot 53.0
376Phosphoserine (by MAPK) (Potential).Swiss-Prot 53.0
379Phosphoserine (by PKC) (Potential).Swiss-Prot 53.0
391Phosphoserine (by CK2) (Potential).Swiss-Prot 53.0
397Phosphoserine (by CK2) (Potential).Swiss-Prot 53.0
112Phosphotyrosine (Abl)14757045Phospho.ELM 6.0
339Phosphoserine15632197Phospho.ELM 6.0
89Phosphoserine15632197Phospho.ELM 6.0
372Phosphoserine17081983Phospho.ELM 6.0

Methylation Profile   [Top]

There is no record for DCX



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