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Pedican
Pediatric cancer database
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

1576

Name

CYP3A4

Synonymous

CP33|CP34|CYP3A|CYP3A3|CYPIIIA3|CYPIIIA4|HLP|NF-25|P450C3|P450PCN1;cytochrome P450, family 3, subfamily A, polypeptide 4;CYP3A4;cytochrome P450, family 3, subfamily A, polypeptide 4

Definition

P450-III, steroid inducible|albendazole monooxygenase|albendazole sulfoxidase|cytochrome P450 3A3|cytochrome P450 3A4|cytochrome P450 HLp|cytochrome P450 NF-25|cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 3|cytochrome P450, subfamily

Position

7q21.1

Gene Type

protein-coding

Gene Regulation:

Transcription Factors
Post Translational Modification From dbPTM
Methylation Profile From DiseaseMeth database

Transcription Factors   [Top]

Regulation From TransFac database

UDP-glucuronosyltransferase 1-6(h) + CYP3A4(h) <==> UDP-glucuronosyltransferase 1-6(h):CYP3A4(h) (binding)
UGT1A1(h) + CYP3A4(h) <==> UGT1A1(h):CYP3A4(h) (binding)
UGT2B7(h) + CYP3A4(h) <==> UGT2B7(h):CYP3A4(h) (binding)
mPR(h) + CYP3A4(h) <==> mPR(h):CYP3A4(h) (binding)
CYP3A4(h) --> CYP3A4(h) (expression).
CYP3A4(h) --> CYP3A4(h) (expression).
estradiol + O2 + NADPH <--CYP3A4(h)--> 2-hydroxyestradiol-17beta + H2O + NADP+

Post Translational Modification   [Top]

There is no record for CYP3A4

Methylation Profile   [Top]

There is no record for CYP3A4



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