| General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information | |
|---|---|
Gene ID | 156 |
Name | ADRBK1 |
Synonymous | BARK1|BETA-ARK1|GRK2;adrenergic, beta, receptor kinase 1;ADRBK1;adrenergic, beta, receptor kinase 1 |
Definition | G-protein coupled receptor kinase 2|beta-ARK-1|beta-adrenergic receptor kinase 1 |
Position | 11q13.1 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | betaARK-1(h) + RKIP(r){pS153} <==> betaARK-1(h):RKIP(r){pS153} (binding) | betaARK-1(h) + pde6g(m) <==> betaARK-1(h):pde6g(m) (binding) | G-beta-1(h) + betaARK-1(h) <==> G-beta-1(h):betaARK-1(h) (binding) | betaARK-1(h) --> ERK1(h){p} (decrease of phosphorylation) | betaARK-1(h) --> ERK2(h){p} (decrease of phosphorylation) | betaARK-1(h) + CD3epsilon(h) <==> betaARK-1(h):CD3epsilon(h) (binding) | ADRBK1(h) --> betaARK-1(h) (expression). | TSH(b) --> betaARK-1(h) (increase of abundance) | rhodopsin(m.s.) + ATP --betaARK-1(h)--> rhodopsin(m.s.){p} + ADP (phosphorylation) | ADRBK1(h) --> betaARK-1(h) (expression). | PDGFRbeta(h) + ATP --betaARK-1(h)--> PDGFRbeta(h){pS} + ADP (phosphorylation) | rhodopsin(mo) + ATP --betaARK-1(h)--> rhodopsin(mo){p} + ADP (phosphorylation) |
|---|
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 29 | Phosphoserine (PKC alpha) | 11042191 | Phospho.ELM 6.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr11 |
Promoter: 66789169 - 66791169 | Agilent_014791 |
chr11 |
Promoter: 66789169 - 66791169 | GSE27584 |
chr11 |
Promoter: 66789169 - 66791169 | Agilent_014791_44K |