Pediatric cancer gene database (Pedican) Home
Pedican
Pediatric cancer database
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

156

Name

ADRBK1

Synonymous

BARK1|BETA-ARK1|GRK2;adrenergic, beta, receptor kinase 1;ADRBK1;adrenergic, beta, receptor kinase 1

Definition

G-protein coupled receptor kinase 2|beta-ARK-1|beta-adrenergic receptor kinase 1

Position

11q13.1

Gene Type

protein-coding

Gene Regulation:

Transcription Factors
Post Translational Modification From dbPTM
Methylation Profile From DiseaseMeth database

Transcription Factors   [Top]

Regulation From TransFac database

betaARK-1(h) + RKIP(r){pS153} <==> betaARK-1(h):RKIP(r){pS153} (binding)
betaARK-1(h) + pde6g(m) <==> betaARK-1(h):pde6g(m) (binding)
G-beta-1(h) + betaARK-1(h) <==> G-beta-1(h):betaARK-1(h) (binding)
betaARK-1(h) --> ERK1(h){p} (decrease of phosphorylation)
betaARK-1(h) --> ERK2(h){p} (decrease of phosphorylation)
betaARK-1(h) + CD3epsilon(h) <==> betaARK-1(h):CD3epsilon(h) (binding)
ADRBK1(h) --> betaARK-1(h) (expression).
TSH(b) --> betaARK-1(h) (increase of abundance)
rhodopsin(m.s.) + ATP --betaARK-1(h)--> rhodopsin(m.s.){p} + ADP (phosphorylation)
ADRBK1(h) --> betaARK-1(h) (expression).
PDGFRbeta(h) + ATP --betaARK-1(h)--> PDGFRbeta(h){pS} + ADP (phosphorylation)
rhodopsin(mo) + ATP --betaARK-1(h)--> rhodopsin(mo){p} + ADP (phosphorylation)

Post Translational Modification   [Top]

Location (AA)

PTM type

Literature

Database

29Phosphoserine (PKC alpha)11042191Phospho.ELM 6.0

Methylation Profile   [Top]

Chromosome

Location

Source

chr11

Promoter: 66789169 - 66791169Agilent_014791

chr11

Promoter: 66789169 - 66791169GSE27584

chr11

Promoter: 66789169 - 66791169Agilent_014791_44K


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