| General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information | |
|---|---|
Gene ID | 1438 |
Name | CSF2RA |
Synonymous | CD116|CDw116|CSF2R|CSF2RAX|CSF2RAY|CSF2RX|CSF2RY|GM-CSF-R-alpha|GMCSFR|GMR|SMDP4;colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage);CSF2RA;colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) |
Definition | CD116 antigen|GM-CSF receptor alpha subunit|GMCSFR-alpha|GMR-alpha|colony stimulating factor 2 receptor alpha subunit|granulocyte-macrophage colony-stimulating factor receptor alpha chain|granulocyte-macrophage colony-stimulating factor receptor subunit a |
Position | Xp22.32 and Yp11.3 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | GM-CSFRalpha(h) --> Abeta40(h) (increase of abundance) | GM-CSFRalpha(h) --> Abeta42(h) (increase of abundance) | GM-CSFRalpha(h) --> APP770(h) (increase of abundance) | GM-CSFRalpha(h) --/ APP(h) (decrease of abundance) | IL-5Rbeta(h) + GM-CSFRalpha(h) <==> IL-5Rbeta(h):GM-CSFRalpha(h) (binding) | CSF2RA(h) --> GM-CSFRalpha(h) (expression). | GM-CSF(m.s.) --/ GM-CSFRalpha(h) (decrease of abundance) | c-Kit(m) + GM-CSFRalpha-isoform1(h) <==> c-Kit(m):GM-CSFRalpha-isoform1(h) (binding) | GM-CSFRalpha-isoform1(h) --> c-Kit(m){p} (decrease of phosphorylation) | CSF2RA(h) --> GM-CSFRalpha-isoform1(h) (expression). | CSF2RA(h) --> GM-CSFRalpha-isoform2(h) (expression). | CSF2RA(h) --> GM-CSFRalpha-isoform3(h) (expression). | CSF2RA(h) --> GM-CSFRalpha-isoform4(h) (expression). | CSF2RA(h) --> GM-CSFRalpha-isoform5(h) (expression). | CSF2RA(h) --> GM-CSFRalpha-isoform6(h) (expression). |
|---|
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 46 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 54 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 99 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 123 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 135 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 182 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 195 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 223 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 229 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 272 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 305 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
There is no record for CSF2RA | ||