| General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information | |
|---|---|
Gene ID | 1278 |
Name | COL1A2 |
Synonymous | OI4;collagen, type I, alpha 2;COL1A2;collagen, type I, alpha 2 |
Definition | alpha 2(I)-collagen|alpha-2 type I collagen|collagen I, alpha-2 polypeptide|collagen alpha-2(I) chain|collagen of skin, tendon and bone, alpha-2 chain|type I procollagen |
Position | 7q22.1 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | COL1A2(h) --> col1a2(h) (expression). | TGFbeta1(m.s.) --> col1a2(h) (increase of abundance) | p300(m.s.) --> col1a2(h) (increase of abundance) |
|---|
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 80 | Pyrrolidone carboxylic acid (Bysimilarity). | Swiss-Prot 53.0 | 84 | Allysine. | Swiss-Prot 53.0 | 420 | Hydroxyproline. | Swiss-Prot 53.0 | 441 | Hydroxyproline. | Swiss-Prot 53.0 | 444 | Hydroxyproline. | Swiss-Prot 53.0 | 1267 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr7 |
Promoter: 93860309 - 93862309 | GoldenGate_Methylation_Cancer_Panel_I |
chr7 |
Promoter: 93860309 - 93862309 | GSE27584 |
chr7 |
Promoter: 93860309 - 93862309 | PMID:15911243 |
chr7 |
Promoter: 93860309 - 93862309 | PMID:12702564 |