| General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information | |
|---|---|
Gene ID | 10014 |
Name | HDAC5 |
Synonymous | HD5|NY-CO-9;histone deacetylase 5;HDAC5;histone deacetylase 5 |
Definition | antigen NY-CO-9 |
Position | 17q21 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | GATA-2(h) + HDAC5(h) <==> GATA-2(h):HDAC5(h) (binding) | HDAC5(h) --Caspase-3(h)--> HDAC5-p97(h) + protein remnants (processing) | HDAC5(h) + cyclinD1(h) <==> HDAC5(h):cyclinD1(h) (binding) | HDAC5(h) + NCOR1-isoform1(m) <==> HDAC5(h):NCOR1-isoform1(m) (binding) | HDAC5(h) + HDAC3(h) <==> HDAC5(h):HDAC3(h) (binding) | OGG1-1A(h) + HDAC5(h) <==> OGG1-1A(h):HDAC5(h) (binding) | Tbx3(h) + HDAC5(h) <==> Tbx3(h):HDAC5(h) (binding) | HDAC5(h) --> HDAC5(h) (expression). | Hp1-alpha(m) + HDAC5(h) <==> Hp1-alpha(m):HDAC5(h) (binding) | Hp1-beta(m) + HDAC5(h) <==> Hp1-beta(m):HDAC5(h) (binding) | Hp1-gamma(m) + HDAC5(h) <==> Hp1-gamma(m):HDAC5(h) (binding) | HDAC5(h) + SUV39H1(m.s.) <==> HDAC5(h):SUV39H1(m.s.) (binding) | HDAC5(h) + BCOR-isoform2(h) <==> HDAC5(h):BCOR-isoform2(h) (binding) | HDAC5(h) + BCOR-S(h) <==> HDAC5(h):BCOR-S(h) (binding) | HDAC5(h) + GATA-1(m) <==> HDAC5(h):GATA-1(m) (binding) | HDAC5(h) --> HDAC5(h) (translocation) | HDAC5(h) --> HDAC5(h) (translocation) | HDAC5(h) --> HDAC5(h) (expression). | Hp1-alpha(m):HDAC5(h) <==> HDAC5(h) + Hp1-alpha(m) (dissociation) | HDAC5(h) --> HDAC5(h) (translocation) | HDAC5(h) --> HDAC5(h) (translocation) |
|---|
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 259 | Phosphoserine (by CaMK). | Swiss-Prot 53.0 | 498 | Phosphoserine (by CaMK). | Swiss-Prot 53.0 | 259 | Phosphoserine (CaM-KIV) | 11081517 | Phospho.ELM 6.0 | 498 | Phosphoserine (CaM-KIV) | 11081517 | Phospho.ELM 6.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr17 |
Promoter: 39556040 - 39558040 | Agilent_014791 |
chr17 |
Promoter: 39556040 - 39558040 | GoldenGate_Methylation_Cancer_Panel_I |
chr17 |
Promoter: 39556040 - 39558040 | GoldenGate_Methylation_Cancer_Panel_I |
chr17 |
Promoter: 39556040 - 39558040 | GSE27584 |
chr17 |
Promoter: 39556040 - 39558040 | GSE27584 |
chr17 |
Promoter: 39556040 - 39558040 | Agilent_014791 |