Pediatric cancer gene database (Pedican) Home
Pedican
Pediatric cancer database
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

6545

Name

SLC7A4

Synonymous

CAT-4|CAT4|HCAT3|VH;solute carrier family 7 (orphan transporter), member 4;SLC7A4;solute carrier family 7 (orphan transporter), member 4

Definition

Ig heavy chain variable region|VH 3 family|cationic amino acid transporter 4|solute carrier family 7 (cationic amino acid transporter, y+ system), member 4|solute carrier family 7 member 4

Position

22q11.21

Gene Type

protein-coding

Gene Mutation:

PCGP germline mutation
PCGP somatic mutation
COSMIC somatic mutation

PCGP germline mutation   [Top]

There is no record for SLC7A4

PCGP somatic mutation   [Top]

There is no record for SLC7A4

COSMIC somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

c.468C>A; p.H156Q; 22:19715634-19715634

 lungcarcinoma; adenocarcinoma

c.342G>A; p.W114*;

NSmalignant_melanoma

c.342G>A; p.W114*;

NSmalignant_melanoma

c.1796G>T; p.G599V;

large_intestine; coloncarcinoma; adenocarcinoma

c.983C>T; p.A328V;

large_intestine; coloncarcinoma; adenocarcinoma

c.638G>T; p.G213V;

haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; plasma_cell_myeloma

c.314T>A; p.F105Y;

haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma

c.757G>A; p.V253I;

oesophagus; lower_thirdcarcinoma; adenocarcinoma

c.169G>A; p.V57M;

oesophagus; lower_thirdcarcinoma; adenocarcinoma

c.735C>T; p.F245F;

lungcarcinoma; adenocarcinoma

c.1752C>G; p.G584G;

lungcarcinoma; adenocarcinoma

c.1816G>A; p.V606M;

lungcarcinoma; adenocarcinoma

c.265T>A; p.Y89N;

lungcarcinoma; adenocarcinoma

c.1781A>T; p.Q594L;

lungcarcinoma; adenocarcinoma

c.58C>G; p.R20G;

autonomic_ganglianeuroblastoma

c.1507C>T; p.L503L;

breastcarcinoma

c.1054C>A; p.L352I;

breastcarcinoma

c.479G>C; p.W160S;

breastcarcinoma; basal_(triple-negative)_carcinoma

c.1479C>G; p.G493G;

lungcarcinoma; adenocarcinoma

c.1119G>C; p.A373A; 22:19714504-19714504

 ovarycarcinoma; serous_carcinoma

c.402C>T; p.A134A;

lungcarcinoma; squamous_cell_carcinoma

c.403C>T; p.R135C;

lungcarcinoma; squamous_cell_carcinoma

c.1390C>A; p.P464T;

lungcarcinoma; squamous_cell_carcinoma

c.1321C>A; p.H441N;

lungcarcinoma; squamous_cell_carcinoma

c.714_715GG>AT; p.M238_A239>IS;

lung; right_upper_lobecarcinoma; adenocarcinoma

c.522T>C; p.A174A;

lung; right_lower_lobecarcinoma; adenocarcinoma

c.177A>T; p.T59T;

lung; right_upper_lobecarcinoma; adenocarcinoma

c.387T>C; p.G129G;

large_intestine; caecumcarcinoma; adenocarcinoma

c.83C>T; p.T28I;

breastcarcinoma

c.1709G>A; p.R570H;

endometriumcarcinoma; endometrioid_carcinoma

c.322G>A; p.V108I;

endometriumcarcinoma; endometrioid_carcinoma

c.1708C>T; p.R570C;

large_intestine; caecumcarcinoma; adenocarcinoma

c.1025G>A; p.R342H;

endometriumcarcinoma; endometrioid_carcinoma

c.1435A>G; p.T479A;

large_intestine; caecumcarcinoma; adenocarcinoma

c.1833C>T; p.G611G;

large_intestine; coloncarcinoma; adenocarcinoma

c.279G>A; p.G93G;

kidneycarcinoma; clear_cell_renal_cell_carcinoma

c.103C>T; p.R35C;

endometriumcarcinoma; endometrioid_carcinoma

c.296C>T; p.T99M;

endometriumcarcinoma; endometrioid_carcinoma

c.824C>T; p.S275L;

large_intestine; coloncarcinoma; adenocarcinoma

c.1337G>A; p.G446D;

prostatecarcinoma; adenocarcinoma

c.729C>G; p.S243S;

kidneycarcinoma; clear_cell_renal_cell_carcinoma

c.1291delC; p.L431fs*1;

large_intestine; caecumcarcinoma; adenocarcinoma

c.598G>A; p.A200T;

endometriumcarcinoma; endometrioid_carcinoma

c.982G>A; p.A328T;

endometriumcarcinoma; endometrioid_carcinoma

c.394G>A; p.A132T;

breastcarcinoma

c.1347C>T; p.H449H;

large_intestine; rectumcarcinoma; adenocarcinoma

c.1503G>A; p.S501S;

urinary_tract; bladdercarcinoma

c.465C>T; p.T155T;

prostatecarcinoma

c.1704G>A; p.W568*;

stomachadenocarcinoma

c.981C>T; p.C327C;

stomachadenocarcinoma

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