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Pedican
Pediatric cancer database
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

5584

Name

PRKCI

Synonymous

DXS1179E|PKCI|nPKC-iota;protein kinase C, iota;PRKCI;protein kinase C, iota

Definition

PRKC-lambda/iota|aPKC-lambda/iota|atypical protein kinase C-lambda/iota|protein kinase C iota type

Position

3q26.3

Gene Type

protein-coding

Gene Mutation:

PCGP germline mutation
PCGP somatic mutation
COSMIC somatic mutation

PCGP germline mutation   [Top]

There is no record for PRKCI

PCGP somatic mutation   [Top]

There is no record for PRKCI

COSMIC somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

c.1048C>T; p.L350F;

breastcarcinoma; basal_(triple-negative)_carcinoma

c.1387G>C; p.D463H;

lungcarcinoma; small_cell_carcinoma

c.1387G>C; p.D463H;

lungcarcinoma; small_cell_carcinoma

c.1188C>G; p.D396E;

salivary_glandcarcinoma; adenoid_cystic_carcinoma

c.1289A>G; p.Y430C; 3:171492421-171492421

 lungcarcinoma; adenocarcinoma

c.574C>T; p.R192W;

large_intestine; coloncarcinoma; adenocarcinoma

c.1192G>A; p.G398S;

large_intestine; coloncarcinoma; adenocarcinoma

c.334C>T; p.R112C;

haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma

c.1438C>A; p.R480S;

oesophagus; lower_thirdcarcinoma; adenocarcinoma

c.1203+3G>T; p.?;

livercarcinoma

c.1438C>T; p.R480C; 3:171496413-171496413

 large_intestine; coloncarcinoma; adenocarcinoma

c.1076C>G; p.S359C;

upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinoma

c.353C>T; p.P118L; 3:171463900-171463900

 skinmalignant_melanoma

c.111G>T; p.M37I;

lungcarcinoma; adenocarcinoma

c.948T>A; p.V316V;

lungcarcinoma; adenocarcinoma

c.1726C>T; p.Q576*;

skin; extremitymalignant_melanoma

c.361G>C; p.D121H;

breastcarcinoma

c.1511G>A; p.R504Q;

prostatecarcinoma

c.1100A>G; p.N367S;

livercarcinoma

c.223G>T; p.G75*;

lungcarcinoma; adenocarcinoma

c.1188C>A; p.D396E;

lungcarcinoma; adenocarcinoma

c.1438C>T; p.R480C; 3:171496413-171496413

 ovarycarcinoma; serous_carcinoma

c.1008T>G; p.N336K;

ovarycarcinoma; serous_carcinoma

c.1119G>A; p.G373G;

lungcarcinoma; squamous_cell_carcinoma

c.1703+2T>G; p.?;

lungcarcinoma; squamous_cell_carcinoma

c.801A>T; p.K267N;

lungcarcinoma; squamous_cell_carcinoma

c.1642G>T; p.G548C;

lungcarcinoma; squamous_cell_carcinoma

c.1279G>A; p.G427R;

lungcarcinoma; squamous_cell_carcinoma

c.1307G>T; p.W436L;

lung; right_lower_lobecarcinoma; adenocarcinoma

c.846G>C; p.M282I;

lungcarcinoma; squamous_cell_carcinoma

c.1675G>C; p.E559Q;

lungcarcinoma; adenocarcinoma

c.1390C>A; p.Q464K;

lungcarcinoma; adenocarcinoma

c.1269A>T; p.E423D;

lung; right_upper_lobecarcinoma; adenocarcinoma

c.382G>T; p.G128C;

lung; right_upper_lobecarcinoma; adenocarcinoma

c.895G>A; p.V299I;

lung; right_upper_lobecarcinoma; adenocarcinoma

c.335G>A; p.R112H;

endometriumcarcinoma; endometrioid_carcinoma

c.433G>A; p.A145T;

large_intestine; coloncarcinoma; adenocarcinoma

c.819delA; p.T276fs*7;

large_intestine; coloncarcinoma; adenocarcinoma

c.1215G>A; p.R405R;

large_intestine; coloncarcinoma; adenocarcinoma

c.1438C>T; p.R480C; 3:171496413-171496413

 large_intestine; coloncarcinoma; adenocarcinoma

c.706-1G>T; p.?;

large_intestine; caecumcarcinoma; adenocarcinoma

c.795T>A; p.Y265*;

large_intestine; caecumcarcinoma; adenocarcinoma

c.815G>C; p.R272P;

large_intestine; caecumcarcinoma; adenocarcinoma

c.354A>G; p.P118P;

large_intestine; coloncarcinoma; adenocarcinoma

c.335G>A; p.R112H;

large_intestine; coloncarcinoma; adenocarcinoma

c.1438C>T; p.R480C; 3:171496413-171496413

 large_intestine; coloncarcinoma; adenocarcinoma

c.832C>T; p.R278C;

large_intestine; coloncarcinoma; adenocarcinoma

c.736T>G; p.S246A;

endometriumcarcinoma; endometrioid_carcinoma

c.1377C>T; p.S459S;

endometriumcarcinoma; endometrioid_carcinoma

c.1540G>C; p.A514P;

breastcarcinoma

c.1440C>T; p.R480R;

large_intestine; caecumcarcinoma; adenocarcinoma

c.354A>G; p.P118P;

large_intestine; caecumcarcinoma; adenocarcinoma

c.353C>T; p.P118L; 3:171463900-171463900

 large_intestine; caecumcarcinoma; adenocarcinoma

c.1647G>T; p.L549F;

endometriumcarcinoma; endometrioid_carcinoma

c.1230C>G; p.T410T;

endometriumcarcinoma; endometrioid_carcinoma

c.660T>G; p.N220K;

endometriumcarcinoma; endometrioid_carcinoma

c.1568G>A; p.R523Q;

endometriumcarcinoma; endometrioid_carcinoma

c.354A>G; p.P118P;

large_intestine; coloncarcinoma; adenocarcinoma

c.354A>G; p.P118P;

large_intestine; coloncarcinoma; adenocarcinoma

c.818_819insA; p.T276fs*16;

large_intestine; coloncarcinoma; adenocarcinoma

c.818_819insA; p.T276fs*16;

large_intestine; coloncarcinoma; adenocarcinoma

c.1289A>G; p.Y430C; 3:171492421-171492421

 large_intestine; caecumcarcinoma; adenocarcinoma

c.353C>A; p.P118Q;

large_intestine; coloncarcinoma; adenocarcinoma

c.815G>C; p.R272P;

large_intestine; coloncarcinoma; adenocarcinoma

c.894G>T; p.W298C;

kidneycarcinoma; clear_cell_renal_cell_carcinoma

c.608T>C; p.M203T;

endometriumcarcinoma; endometrioid_carcinoma

c.1631C>A; p.S544Y;

endometriumcarcinoma; endometrioid_carcinoma

c.545G>A; p.C182Y;

endometriumcarcinoma; endometrioid_carcinoma

c.1560G>C; p.P520P;

endometriumcarcinoma; endometrioid_carcinoma

c.61G>T; p.D21Y;

large_intestine; caecumcarcinoma; adenocarcinoma

c.1288T>C; p.Y430H;

large_intestine; coloncarcinoma; adenocarcinoma

c.1375T>C; p.S459P;

large_intestine; caecumcarcinoma; adenocarcinoma

c.1439G>A; p.R480H;

large_intestine; caecumcarcinoma; adenocarcinoma

c.1290T>C; p.Y430Y;

large_intestine; rectumcarcinoma; adenocarcinoma

c.1439G>T; p.R480L;

large_intestine; rectumcarcinoma; adenocarcinoma

c.1448G>A; p.R483H;

large_intestine; coloncarcinoma; adenocarcinoma

c.819delA; p.T276fs*7;

large_intestine; caecumcarcinoma; adenocarcinoma

c.573G>A; p.G191G;

prostatecarcinoma

c.826_827insAA; p.T276fs*8;

prostatecarcinoma

c.535C>T; p.H179Y;

skinmalignant_melanoma

c.943C>T; p.L315F;

skinmalignant_melanoma

c.819delA; p.T276fs*7;

stomachadenocarcinoma

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