| General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information | |
|---|---|
Gene ID | 3146 |
Name | HMGB1 |
Synonymous | HMG1|HMG3|SBP-1;high mobility group box 1;HMGB1;high mobility group box 1 |
Definition | Amphoterin|HMG-1|Sulfoglucuronyl carbohydrate binding protein|high mobility group protein 1|high mobility group protein B1|high-mobility group (nonhistone chromosomal) protein 1|high-mobility group box 1 |
Position | 13q12 |
Gene Type | protein-coding |
Gene Mutation: | PCGP germline mutation PCGP somatic mutation COSMIC somatic mutation |
PCGP germline mutation [Top] | ||
There is no record for HMGB1 | ||
PCGP somatic mutation [Top] | ||
There is no record for HMGB1 | ||
COSMIC somatic mutation [Top] | ||
Mutation (CDS; AA; Chr) | Site | Histology |
|---|---|---|
c.374T>A; p.V125D; |
haematopoietic_and_lymphoid_tissue; lymph_node | lymphoid_neoplasm; diffuse_large_B_cell_lymphoma |
c.313T>C; p.F105L; |
haematopoietic_and_lymphoid_tissue; lymph_node | lymphoid_neoplasm; diffuse_large_B_cell_lymphoma |
c.71G>A; p.R24Q; |
haematopoietic_and_lymphoid_tissue | haematopoietic_neoplasm; acute_myeloid_leukaemia |
c.151A>T; p.T51S; |
bone | chondrosarcoma |
c.296+1G>A; p.?; 13:29935343-29935343 |
ovary | carcinoma; serous_carcinoma |
c.312C>A; p.L104L; |
lung | carcinoma; squamous_cell_carcinoma |
c.177A>G; p.K59K; |
endometrium | carcinoma; endometrioid_carcinoma |
c.131A>C; p.K44T; |
large_intestine; colon | carcinoma; adenocarcinoma |
c.443C>G; p.A148G; |
large_intestine; colon | carcinoma; adenocarcinoma |
c.378G>A; p.A126A; |
large_intestine; rectum | carcinoma; adenocarcinoma |
c.584A>G; p.E195G; |
endometrium | carcinoma; endometrioid_carcinoma |
c.253A>G; p.T85A; |
endometrium | carcinoma; endometrioid_carcinoma |
c.296+1G>A; p.?; 13:29935343-29935343 |
endometrium | carcinoma; endometrioid_carcinoma |
c.488G>A; p.R163Q; |
endometrium | carcinoma; endometrioid_carcinoma |
c.378G>A; p.A126A; |
large_intestine; colon | carcinoma; adenocarcinoma |
c.333A>G; p.P111P; |
endometrium | carcinoma; endometrioid_carcinoma |
c.328C>T; p.R110C; |
endometrium | carcinoma; endometrioid_carcinoma |
c.120G>C; p.E40D; |
breast | carcinoma |
c.597G>T; p.E199D; |
endometrium | carcinoma; endometrioid_carcinoma |
c.242C>T; p.P81L; |
skin | malignant_melanoma |
c.297-3delt; p.?; |
stomach | adenocarcinoma |