| General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information | |
|---|---|
Gene ID | 8743 |
Name | TNFSF10 |
Synonymous | APO2L|Apo-2L|CD253|TL2|TRAIL;tumor necrosis factor (ligand) superfamily, member 10;TNFSF10;tumor necrosis factor (ligand) superfamily, member 10 |
Definition | Apo-2 ligand|TNF-related apoptosis inducing ligand TRAIL|chemokine tumor necrosis factor ligand superfamily member 10|tumor necrosis factor (ligand) family, member 10|tumor necrosis factor apoptosis-inducing ligand splice variant delta|tumor necrosis fact |
Position | 3q26 |
Gene Type | protein-coding |
Gene Interactions: | Physical Interaction Metabolic Interaction Signaling Interaction |
Physical Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
in same component |
CASP10 | REACTOME; |
in same component |
CASP8 | REACTOME; |
in same component |
DAP3 | NCI_NATURE; |
in same component |
FADD | NCI_NATURE; |
in same component |
FADD | REACTOME; |
in same component |
RIPK1 | NCI_NATURE; |
in same component |
TNFRSF10A | NCI_NATURE; |
in same component |
TNFRSF10B | NCI_NATURE; |
in same component |
TNFRSF10B | REACTOME; |
in same component |
TNFRSF10C | NCI_NATURE; |
in same component |
TNFRSF10D | NCI_NATURE; |
in same component |
TRADD | NCI_NATURE; |
in same component |
TRAF2 | NCI_NATURE; |
interacts with |
ACP5 | BIOGRID; |
interacts with |
ACP5 | HPRD; |
interacts with |
ACP5 | MINT; |
interacts with |
C7orf64 | BIOGRID; |
interacts with |
C7orf64 | HPRD; |
interacts with |
TNFRSF10A | BIOGRID; |
interacts with |
TNFRSF10A | HPRD; |
interacts with |
TNFRSF10B | BIOGRID; |
interacts with |
TNFRSF10B | HPRD; |
interacts with |
TNFRSF10B | MINT; |
interacts with |
TNFRSF10C | HPRD; |
interacts with |
TNFRSF10D | BIOGRID; |
interacts with |
TNFRSF10D | HPRD; |
interacts with |
TNFRSF11B | HPRD; |
Metabolic Interaction [Top] | ||
There is no record for TNFSF10 | ||
Signaling Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
reacts with |
CASP10 | REACTOME; |
reacts with |
CASP8 | REACTOME; |
reacts with |
DAP3 | NCI_NATURE; |
reacts with |
FADD | NCI_NATURE; |
reacts with |
FADD | REACTOME; |
reacts with |
RIPK1 | NCI_NATURE; |
reacts with |
TNFRSF10A | NCI_NATURE; |
reacts with |
TNFRSF10B | NCI_NATURE; |
reacts with |
TNFRSF10B | REACTOME; |
reacts with |
TNFRSF10C | NCI_NATURE; |
reacts with |
TNFRSF10D | NCI_NATURE; |
reacts with |
TNFSF10 | NCI_NATURE; |
reacts with |
TNFSF10 | REACTOME; |
reacts with |
TRADD | NCI_NATURE; |
reacts with |
TRAF2 | NCI_NATURE; |
state change |
CFLAR | REACTOME; |