| General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information | |
|---|---|
Gene ID | 843 |
Name | CASP10 |
Synonymous | ALPS2|FLICE2|MCH4;caspase 10, apoptosis-related cysteine peptidase;CASP10;caspase 10, apoptosis-related cysteine peptidase |
Definition | CASP-10|FADD-like ICE2|FAS-associated death domain protein interleukin-1B-converting enzyme 2|ICE-like apoptotic protease 4|apoptotic protease MCH-4|caspase 10, apoptosis-related cysteine protease|caspase-10|interleukin-1B-converting enzyme 2 |
Position | 2q33-q34 |
Gene Type | protein-coding |
Gene Interactions: | Physical Interaction Metabolic Interaction Signaling Interaction |
Physical Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
in same component |
FADD | CELL_MAP; |
in same component |
FADD | NCI_NATURE; |
in same component |
FADD | REACTOME; |
in same component |
FAS | NCI_NATURE; |
in same component |
FAS | REACTOME; |
in same component |
FASLG | NCI_NATURE; |
in same component |
FASLG | REACTOME; |
in same component |
RIPK1 | CELL_MAP; |
in same component |
TNFRSF10B | REACTOME; |
in same component |
TNFSF10 | REACTOME; |
in same component |
TRADD | CELL_MAP; |
in same component |
TRAF2 | CELL_MAP; |
interacts with |
ARHGDIA | BIOGRID; |
interacts with |
BFAR | HPRD; |
interacts with |
BID | BIOGRID; |
interacts with |
CASP14 | BIOGRID; |
interacts with |
CASP14 | HPRD; |
interacts with |
CASP1 | BIOGRID; |
interacts with |
CASP2 | BIOGRID; |
interacts with |
CASP3 | BIOGRID; |
interacts with |
CASP3 | HPRD; |
interacts with |
CASP4 | BIOGRID; |
interacts with |
CASP4 | HPRD; |
interacts with |
CASP6 | BIOGRID; |
interacts with |
CASP6 | HPRD; |
interacts with |
CASP7 | BIOGRID; |
interacts with |
CASP7 | HPRD; |
interacts with |
CASP8 | BIOGRID; |
interacts with |
CASP8 | CELL_MAP; |
interacts with |
CASP8 | HPRD; |
interacts with |
CASP8 | MINT; |
interacts with |
CASP9 | BIOGRID; |
interacts with |
CASP9 | HPRD; |
interacts with |
CCAR1 | HPRD; |
interacts with |
CFLAR | BIOGRID; |
interacts with |
CFLAR | HPRD; |
interacts with |
DEDD2 | BIOGRID; |
interacts with |
DEDD2 | HPRD; |
interacts with |
DEDD | BIOGRID; |
interacts with |
DEDD | HPRD; |
interacts with |
Dlg4 | MINT; |
interacts with |
DSP | HPRD; |
interacts with |
EZR | BIOGRID; |
interacts with |
FADD | BIOGRID; |
interacts with |
FADD | HPRD; |
interacts with |
FADD | MINT; |
interacts with |
FAS | BIOGRID; |
interacts with |
FASLG | BIOGRID; |
interacts with |
FASLG | MINT; |
interacts with |
MAP3K14 | BIOGRID; |
interacts with |
MAPK8 | BIOGRID; |
interacts with |
MSN | BIOGRID; |
interacts with |
POLR2A | HPRD; |
interacts with |
RB1 | HPRD; |
interacts with |
RHOA | BIOGRID; |
interacts with |
RIPK1 | BIOGRID; |
interacts with |
RYBP | BIOGRID; |
interacts with |
RYBP | HPRD; |
interacts with |
TNFRSF10A | BIOGRID; |
interacts with |
TNFRSF10A | HPRD; |
interacts with |
TNFRSF10B | BIOGRID; |
interacts with |
TNFRSF10B | HPRD; |
interacts with |
TNFRSF1A | BIOGRID; |
interacts with |
TNFRSF1A | HPRD; |
interacts with |
TRAF1 | BIOGRID; |
interacts with |
TRAF1 | HPRD; |
Metabolic Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
metabolic catalysis |
FADD | REACTOME; |
metabolic catalysis |
MAVS | REACTOME; |
metabolic catalysis |
RIPK1 | REACTOME; |
metabolic catalysis |
TP53 | NCI_NATURE; |
Signaling Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
reacts with |
CASP10 | NCI_NATURE; |
reacts with |
CASP10 | REACTOME; |
reacts with |
CASP8 | REACTOME; |
reacts with |
CFLAR | NCI_NATURE; |
reacts with |
FADD | NCI_NATURE; |
reacts with |
FADD | REACTOME; |
reacts with |
FAS | NCI_NATURE; |
reacts with |
FAS | REACTOME; |
reacts with |
FASLG | NCI_NATURE; |
reacts with |
FASLG | REACTOME; |
reacts with |
MAVS | REACTOME; |
reacts with |
RIPK1 | REACTOME; |
reacts with |
TNFRSF10B | REACTOME; |
reacts with |
TNFSF10 | REACTOME; |
state change |
FADD | NCI_NATURE; |
state change |
GZMB | NCI_NATURE; |
state change |
TNFRSF10A | NCI_NATURE; |
state change |
TNFRSF10B | NCI_NATURE; |
state change |
TNFRSF10D | NCI_NATURE; |
state change |
TNFSF10 | NCI_NATURE; |