| General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information | |
|---|---|
Gene ID | 7852 |
Name | CXCR4 |
Synonymous | CD184|D2S201E|FB22|HM89|HSY3RR|LAP3|LCR1|LESTR|NPY3R|NPYR|NPYRL|NPYY3R|WHIM;chemokine (C-X-C motif) receptor 4;CXCR4;chemokine (C-X-C motif) receptor 4 |
Definition | C-X-C chemokine receptor type 4|CD184 antigen|CXC-R4|CXCR-4|SDF-1 receptor|fusin|leukocyte-derived seven transmembrane domain receptor|leukocyte-derived seven-transmembrane-domain receptor|lipopolysaccharide-associated protein 3|neuropeptide Y receptor Y3 |
Position | 2q21 |
Gene Type | protein-coding |
Gene Interactions: | Physical Interaction Metabolic Interaction Signaling Interaction |
Physical Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
in same component |
CXCL12 | NCI_NATURE; |
in same component |
JAK2 | NCI_NATURE; |
in same component |
PTPRC | NCI_NATURE; |
in same component |
SDC4 | NCI_NATURE; |
in same component |
VAV1 | NCI_NATURE; |
interacts with |
ADRBK2 | BIOGRID; |
interacts with |
ARRB2 | HPRD; |
interacts with |
CCR5 | BIOGRID; |
interacts with |
CCR5 | HPRD; |
interacts with |
CD4 | BIOGRID; |
interacts with |
CD4 | HPRD; |
interacts with |
CD74 | MINT; |
interacts with |
CTSG | HPRD; |
interacts with |
CXCL12 | HPRD; |
interacts with |
DPP4 | HPRD; |
interacts with |
ELANE | HPRD; |
interacts with |
GNA13 | HPRD; |
interacts with |
GNAI1 | HPRD; |
interacts with |
HLA-C | BIOGRID; |
interacts with |
HSPA8 | HPRD; |
interacts with |
ITCH | BIOGRID; |
interacts with |
JAK1 | HPRD; |
interacts with |
JAK2 | BIOGRID; |
interacts with |
JAK2 | HPRD; |
interacts with |
JAK3 | BIOGRID; |
interacts with |
JAK3 | HPRD; |
interacts with |
MYH9 | HPRD; |
interacts with |
PTK2 | BIOGRID; |
interacts with |
PTPN11 | HPRD; |
interacts with |
PTPN6 | BIOGRID; |
interacts with |
PTPN6 | HPRD; |
interacts with |
PTPRC | HPRD; |
interacts with |
SDC4 | HPRD; |
interacts with |
SOCS1 | HPRD; |
interacts with |
SOCS3 | BIOGRID; |
interacts with |
SOCS3 | HPRD; |
interacts with |
STAT1 | HPRD; |
interacts with |
STAT2 | HPRD; |
interacts with |
STAT3 | HPRD; |
interacts with |
STAT5B | HPRD; |
interacts with |
TLR2 | INTACT; |
interacts with |
USP14 | BIOGRID; |
interacts with |
VAV1 | HPRD; |
Metabolic Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
metabolic catalysis |
ARNT | NCI_NATURE; |
metabolic catalysis |
HIF1A | NCI_NATURE; |
Signaling Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
reacts with |
CXCL12 | NCI_NATURE; |
reacts with |
CXCR4 | NCI_NATURE; |
reacts with |
JAK2 | NCI_NATURE; |
reacts with |
PTPRC | NCI_NATURE; |
reacts with |
SDC4 | NCI_NATURE; |
reacts with |
VAV1 | NCI_NATURE; |
state change |
ADRBK1 | NCI_NATURE; |
state change |
ARR3 | NCI_NATURE; |
state change |
ARRB2 | NCI_NATURE; |
state change |
DNM1 | NCI_NATURE; |
state change |
GNG2 | NCI_NATURE; |
state change |
GRK6 | NCI_NATURE; |
state change |
HGS | NCI_NATURE; |
state change |
ITCH | NCI_NATURE; |
state change |
S1PR3 | NCI_NATURE; |