| General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information | |
|---|---|
Gene ID | 6696 |
Name | SPP1 |
Synonymous | BNSP|BSPI|ETA-1|OPN;secreted phosphoprotein 1;SPP1;secreted phosphoprotein 1 |
Definition | SPP1/CALPHA1 fusion|bone sialoprotein 1|early T-lymphocyte activation 1|nephropontin|osteopontin|osteopontin-C|osteopontin-D|osteopontin/immunoglobulin alpha 1 heavy chain constant region fusion protein|secreted phosphoprotein 1 (osteopontin, bone sialopr |
Position | 4q22.1 |
Gene Type | protein-coding |
Gene Interactions: | Physical Interaction Metabolic Interaction Signaling Interaction |
Physical Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
in same component |
ITGA4 | NCI_NATURE; |
in same component |
ITGA4 | REACTOME; |
in same component |
ITGA5 | REACTOME; |
in same component |
ITGA8 | NCI_NATURE; |
in same component |
ITGA8 | REACTOME; |
in same component |
ITGA9 | NCI_NATURE; |
in same component |
ITGA9 | REACTOME; |
in same component |
ITGAV | NCI_NATURE; |
in same component |
ITGB1 | NCI_NATURE; |
in same component |
ITGB1 | REACTOME; |
in same component |
ITGB3 | NCI_NATURE; |
interacts with |
ABCF3 | HPRD; |
interacts with |
ABCF3 | MINT; |
interacts with |
ACP5 | HPRD; |
interacts with |
BRE2 | BIOGRID; |
interacts with |
BRE2 | MINT; |
interacts with |
CCT2 | INTACT; |
interacts with |
CCT4 | INTACT; |
interacts with |
CCT7 | INTACT; |
interacts with |
CD44 | HPRD; |
interacts with |
CMK2 | BIOGRID; |
interacts with |
CSNK2A1 | HPRD; |
interacts with |
CSNK2A2 | HPRD; |
interacts with |
CTNNBL1 | BIOGRID; |
interacts with |
CTNNBL1 | HPRD; |
interacts with |
CTNNBL1 | MINT; |
interacts with |
ERF2 | MINT; |
interacts with |
F2 | HPRD; |
interacts with |
GIS2 | BIOGRID; |
interacts with |
HSP78 | BIOGRID; |
interacts with |
HSP78 | INTACT; |
interacts with |
HTB1 | BIOGRID; |
interacts with |
IGFBP5 | BIOGRID; |
interacts with |
IGFBP5 | HPRD; |
interacts with |
ITGA5 | BIOGRID; |
interacts with |
ITGA5 | HPRD; |
interacts with |
ITGA9 | HPRD; |
interacts with |
ITGAV | HPRD; |
interacts with |
ITGB1 | HPRD; |
interacts with |
ITGB3 | HPRD; |
interacts with |
ITGB5 | HPRD; |
interacts with |
ITGB6 | HPRD; |
interacts with |
LGALS1 | HPRD; |
interacts with |
LYS14 | MINT; |
interacts with |
MMP3 | HPRD; |
interacts with |
MMP7 | HPRD; |
interacts with |
MTR2 | BIOGRID; |
interacts with |
MTR2 | MINT; |
interacts with |
ORC2 | BIOGRID; |
interacts with |
ORC3 | BIOGRID; |
interacts with |
PDLIM7 | BIOGRID; |
interacts with |
PDLIM7 | HPRD; |
interacts with |
PDLIM7 | MINT; |
interacts with |
POM33 | BIOGRID; |
interacts with |
POM33 | MINT; |
interacts with |
PRKCA | HPRD; |
interacts with |
PRKG1 | HPRD; |
interacts with |
SDC1 | BIOGRID; |
interacts with |
SDC1 | MINT; |
interacts with |
SET1 | BIOGRID; |
interacts with |
SET1 | MINT; |
interacts with |
SGTA | BIOGRID; |
interacts with |
SGTA | HPRD; |
interacts with |
SGTA | MINT; |
interacts with |
SHG1 | BIOGRID; |
interacts with |
SHG1 | MINT; |
interacts with |
SSA1 | INTACT; |
interacts with |
SSA2 | INTACT; |
interacts with |
SSB1 | INTACT; |
interacts with |
SSB2 | INTACT; |
interacts with |
SSE1 | INTACT; |
interacts with |
SWA2 | INTACT; |
interacts with |
SWD1 | BIOGRID; |
interacts with |
SWD1 | MINT; |
interacts with |
SWD2 | BIOGRID; |
interacts with |
SWD2 | MINT; |
interacts with |
SWD3 | BIOGRID; |
interacts with |
SWD3 | MINT; |
interacts with |
THBS1 | HPRD; |
interacts with |
TPK3 | BIOGRID; |
interacts with |
UBQLN4 | BIOGRID; |
interacts with |
UBQLN4 | HPRD; |
interacts with |
UBQLN4 | MINT; |
interacts with |
VTN | HPRD; |
interacts with |
YCK2 | BIOGRID; |
interacts with |
YDJ1 | INTACT; |
interacts with |
YHI9 | BIOGRID; |
interacts with |
YHI9 | MINT; |
Metabolic Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
metabolic catalysis |
SDC2 | NCI_NATURE; |
metabolic catalysis |
TP53 | NCI_NATURE; |
Signaling Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
reacts with |
ITGA4 | NCI_NATURE; |
reacts with |
ITGA4 | REACTOME; |
reacts with |
ITGA5 | REACTOME; |
reacts with |
ITGA8 | NCI_NATURE; |
reacts with |
ITGA8 | REACTOME; |
reacts with |
ITGA9 | NCI_NATURE; |
reacts with |
ITGA9 | REACTOME; |
reacts with |
ITGAV | NCI_NATURE; |
reacts with |
ITGB1 | NCI_NATURE; |
reacts with |
ITGB1 | REACTOME; |
reacts with |
ITGB3 | NCI_NATURE; |
reacts with |
SPP1 | NCI_NATURE; |
reacts with |
SPP1 | REACTOME; |