| General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information | |
|---|---|
Gene ID | 5159 |
Name | PDGFRB |
Synonymous | CD140B|JTK12|PDGFR|PDGFR-1|PDGFR1;platelet-derived growth factor receptor, beta polypeptide;PDGFRB;platelet-derived growth factor receptor, beta polypeptide |
Definition | CD140 antigen-like family member B|PDGF-R-beta|PDGFR-beta|beta-type platelet-derived growth factor receptor|platelet-derived growth factor receptor 1|platelet-derived growth factor receptor beta |
Position | 5q33.1 |
Gene Type | protein-coding |
Gene Interactions: | Physical Interaction Metabolic Interaction Signaling Interaction |
Physical Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
in same component |
CBL | NCI_NATURE; |
in same component |
DNM2 | NCI_NATURE; |
in same component |
DOCK4 | NCI_NATURE; |
in same component |
GAB1 | NCI_NATURE; |
in same component |
GRB10 | NCI_NATURE; |
in same component |
ITGAV | NCI_NATURE; |
in same component |
ITGB3 | NCI_NATURE; |
in same component |
LRP1 | NCI_NATURE; |
in same component |
PDGFA | NCI_NATURE; |
in same component |
PDGFB | NCI_NATURE; |
in same component |
PDGFC | NCI_NATURE; |
in same component |
PDGFD | NCI_NATURE; |
in same component |
PDGFRA | NCI_NATURE; |
in same component |
PDGFRA | REACTOME; |
in same component |
PLCG1 | NCI_NATURE; |
in same component |
PTEN | NCI_NATURE; |
in same component |
PTPN11 | IMID; |
in same component |
PTPN11 | NCI_NATURE; |
in same component |
RASA1 | NCI_NATURE; |
in same component |
RASA1 | REACTOME; |
in same component |
S1PR1 | NCI_NATURE; |
in same component |
SH2B2 | IMID; |
in same component |
SLC9A3R1 | IMID; |
in same component |
SOS1 | NCI_NATURE; |
in same component |
WASL | NCI_NATURE; |
interacts with |
ADRBK1 | BIOGRID; |
interacts with |
ARAF | HPRD; |
interacts with |
ATP6V0C | MINT; |
interacts with |
BAG1 | HPRD; |
interacts with |
CAV1 | BIOGRID; |
interacts with |
CAV3 | BIOGRID; |
interacts with |
CBLB | HPRD; |
interacts with |
CBL | HPRD; |
interacts with |
CBL | MINT; |
interacts with |
COPA | BIOGRID; |
interacts with |
COPA | HPRD; |
interacts with |
COPB1 | HPRD; |
interacts with |
CRK | BIOGRID; |
interacts with |
CRK | HPRD; |
interacts with |
CRK | MINT; |
interacts with |
EGFR | BIOGRID; |
interacts with |
EGFR | HPRD; |
interacts with |
EIF2AK2 | BIOGRID; |
interacts with |
EIF2AK2 | HPRD; |
interacts with |
FYN | HPRD; |
interacts with |
FYN | MINT; |
interacts with |
GAB1 | HPRD; |
interacts with |
GRB10 | HPRD; |
interacts with |
GRB10 | MINT; |
interacts with |
GRB14 | BIOGRID; |
interacts with |
GRB14 | HPRD; |
interacts with |
GRB7 | HPRD; |
interacts with |
GRB7 | MINT; |
interacts with |
ITGB3 | BIOGRID; |
interacts with |
ITGB3 | HPRD; |
interacts with |
JAK1 | HPRD; |
interacts with |
JAK2 | HPRD; |
interacts with |
KRTAP4-12 | BIOGRID; |
interacts with |
KRTAP4-12 | HPRD; |
interacts with |
KRTAP4-12 | MINT; |
interacts with |
MFGE8 | BIOGRID; |
interacts with |
NCK1 | BIOGRID; |
interacts with |
NCK1 | HPRD; |
interacts with |
NCK1 | MINT; |
interacts with |
NCK2 | BIOGRID; |
interacts with |
NCK2 | HPRD; |
interacts with |
NCK2 | MINT; |
interacts with |
NFKB1 | HPRD; |
interacts with |
PDAP1 | HPRD; |
interacts with |
PDCD6IP | BIOGRID; |
interacts with |
PDGFB | HPRD; |
interacts with |
PDGFD | HPRD; |
interacts with |
PDGFRA | BIOGRID; |
interacts with |
PDGFRA | HPRD; |
interacts with |
PIK3C2B | HPRD; |
interacts with |
PIK3CA | HPRD; |
interacts with |
PIK3R1 | BIOGRID; |
interacts with |
PIK3R1 | HPRD; |
interacts with |
Pik3r1 | MINT; |
interacts with |
PIK3R1 | MINT; |
interacts with |
PIK3R2 | HPRD; |
interacts with |
PIK3R2 | MINT; |
interacts with |
PIK3R3 | HPRD; |
interacts with |
PLCG1 | BIOGRID; |
interacts with |
Plcg1 | MINT; |
interacts with |
PLCG1 | MINT; |
interacts with |
PRDX2 | HPRD; |
interacts with |
PTEN | HPRD; |
interacts with |
PTEN | MINT; |
interacts with |
PTPN11 | BIOGRID; |
interacts with |
PTPN11 | HPRD; |
interacts with |
Ptpn11 | MINT; |
interacts with |
PTPN11 | MINT; |
interacts with |
PTPN12 | INTACT; |
interacts with |
PTPN1 | HPRD; |
interacts with |
Ptpn1 | MINT; |
interacts with |
PTPN1 | MINT; |
interacts with |
RAF1 | BIOGRID; |
interacts with |
RAF1 | HPRD; |
interacts with |
RASA1 | BIOGRID; |
interacts with |
RASA1 | HPRD; |
interacts with |
RASA1 | MINT; |
interacts with |
S1PR1 | BIOGRID; |
interacts with |
S1PR1 | HPRD; |
interacts with |
SH2B2 | MINT; |
interacts with |
SH3KBP1 | BIOGRID; |
interacts with |
SH3KBP1 | HPRD; |
interacts with |
SHC1 | BIOGRID; |
interacts with |
SHC1 | HPRD; |
interacts with |
SLA | MINT; |
interacts with |
SLC9A3R1 | BIOGRID; |
interacts with |
SLC9A3R1 | HPRD; |
interacts with |
SLC9A3R1 | MINT; |
interacts with |
SLC9A3R2 | HPRD; |
interacts with |
SLC9A3R2 | MINT; |
interacts with |
SNX1 | BIOGRID; |
interacts with |
SNX1 | HPRD; |
interacts with |
SNX2 | BIOGRID; |
interacts with |
SNX2 | HPRD; |
interacts with |
SNX4 | BIOGRID; |
interacts with |
SOCS1 | HPRD; |
interacts with |
SRC | BIOGRID; |
interacts with |
SRC | HPRD; |
interacts with |
SRC | MINT; |
interacts with |
STAT1 | HPRD; |
interacts with |
STAT3 | HPRD; |
interacts with |
STAT5A | HPRD; |
interacts with |
STAT5B | HPRD; |
interacts with |
SYNGAP1 | HPRD; |
interacts with |
TYK2 | HPRD; |
interacts with |
VAV1 | BIOGRID; |
interacts with |
VAV2 | BIOGRID; |
interacts with |
VAV3 | BIOGRID; |
interacts with |
YES1 | HPRD; |
interacts with |
YES1 | MINT; |
Metabolic Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
metabolic catalysis |
MAX | NCI_NATURE; |
metabolic catalysis |
MYC | NCI_NATURE; |
metabolic catalysis |
NFYA | NCI_NATURE; |
metabolic catalysis |
NFYB | NCI_NATURE; |
metabolic catalysis |
NFYC | NCI_NATURE; |
Signaling Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
reacts with |
CBL | NCI_NATURE; |
reacts with |
DNM2 | NCI_NATURE; |
reacts with |
DOCK4 | NCI_NATURE; |
reacts with |
GAB1 | NCI_NATURE; |
reacts with |
GRB10 | NCI_NATURE; |
reacts with |
ITGAV | NCI_NATURE; |
reacts with |
ITGB3 | NCI_NATURE; |
reacts with |
LRP1 | NCI_NATURE; |
reacts with |
PDGFA | NCI_NATURE; |
reacts with |
PDGFB | NCI_NATURE; |
reacts with |
PDGFC | NCI_NATURE; |
reacts with |
PDGFD | NCI_NATURE; |
reacts with |
PDGFRA | NCI_NATURE; |
reacts with |
PDGFRA | REACTOME; |
reacts with |
PDGFRB | IMID; |
reacts with |
PDGFRB | NCI_NATURE; |
reacts with |
PDGFRB | REACTOME; |
reacts with |
PLAU | NCI_NATURE; |
reacts with |
PLAUR | NCI_NATURE; |
reacts with |
PLCG1 | NCI_NATURE; |
reacts with |
PTEN | NCI_NATURE; |
reacts with |
PTPN11 | IMID; |
reacts with |
PTPN11 | NCI_NATURE; |
reacts with |
RASA1 | NCI_NATURE; |
reacts with |
RASA1 | REACTOME; |
reacts with |
S1PR1 | NCI_NATURE; |
reacts with |
SH2B2 | IMID; |
reacts with |
SLC9A3R1 | IMID; |
reacts with |
SOS1 | NCI_NATURE; |
reacts with |
WASL | NCI_NATURE; |
state change |
ABL1 | NCI_NATURE; |
state change |
MLLT4 | NCI_NATURE; |
state change |
PDGFRA | REACTOME; |
state change |
PDGFRB | REACTOME; |
state change |
PTPN11 | NCI_NATURE; |
state change |
PTPN1 | NCI_NATURE; |
state change |
PTPRJ | NCI_NATURE; |
state change |
RAC1 | NCI_NATURE; |