| General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information | |
|---|---|
Gene ID | 4846 |
Name | NOS3 |
Synonymous | ECNOS|eNOS;nitric oxide synthase 3 (endothelial cell);NOS3;nitric oxide synthase 3 (endothelial cell) |
Definition | EC-NOS|NOS type III|NOSIII|cNOS|constitutive NOS|endothelial NOS|nitric oxide synthase, endothelial |
Position | 7q36 |
Gene Type | protein-coding |
Gene Interactions: | Physical Interaction Metabolic Interaction Signaling Interaction |
Physical Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
in same component |
AKT1 | REACTOME; |
in same component |
CALM1 | REACTOME; |
in same component |
CAV1 | NCI_NATURE; |
in same component |
CAV1 | REACTOME; |
in same component |
GAB1 | NCI_NATURE; |
in same component |
HSP90AA1 | NCI_NATURE; |
in same component |
HSP90AA1 | REACTOME; |
in same component |
HSP90AB1 | NCI_NATURE; |
in same component |
NOSIP | REACTOME; |
in same component |
NOSTRIN | REACTOME; |
in same component |
PRKACA | NCI_NATURE; |
in same component |
PTPN11 | NCI_NATURE; |
in same component |
WASL | REACTOME; |
interacts with |
AGTR1 | HPRD; |
interacts with |
AKT1 | HPRD; |
interacts with |
BDKRB2 | HPRD; |
interacts with |
BDNF | HPRD; |
interacts with |
CAV1 | BIOGRID; |
interacts with |
CAV1 | HPRD; |
interacts with |
EDNRB | HPRD; |
interacts with |
GUCY1B3 | BIOGRID; |
interacts with |
HSP90AA1 | BIOGRID; |
interacts with |
HSP90AA1 | HPRD; |
interacts with |
NMT1 | HPRD; |
interacts with |
NOSIP | HPRD; |
interacts with |
NOSTRIN | BIOGRID; |
interacts with |
PPP2R5A | HPRD; |
interacts with |
SP1 | HPRD; |
Metabolic Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
metabolic catalysis |
FOSL1 | NCI_NATURE; |
metabolic catalysis |
JUNB | NCI_NATURE; |
Signaling Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
reacts with |
AKT1 | REACTOME; |
reacts with |
CALM1 | REACTOME; |
reacts with |
CAV1 | NCI_NATURE; |
reacts with |
CAV1 | REACTOME; |
reacts with |
GAB1 | NCI_NATURE; |
reacts with |
HSP90AA1 | NCI_NATURE; |
reacts with |
HSP90AA1 | REACTOME; |
reacts with |
HSP90AB1 | NCI_NATURE; |
reacts with |
NOS3 | NCI_NATURE; |
reacts with |
NOS3 | REACTOME; |
reacts with |
NOSIP | REACTOME; |
reacts with |
NOSTRIN | REACTOME; |
reacts with |
PRKACA | NCI_NATURE; |
reacts with |
PTPN11 | NCI_NATURE; |
reacts with |
WASL | REACTOME; |
state change |
AKT1 | NCI_NATURE; |
state change |
CALM1 | NCI_NATURE; |
state change |
ESR1 | NCI_NATURE; |
state change |
ESR2 | NCI_NATURE; |
state change |
GNG2 | NCI_NATURE; |
state change |
KDR | NCI_NATURE; |
state change |
LYPLA1 | REACTOME; |
state change |
PRKACA | NCI_NATURE; |
state change |
PRKCD | NCI_NATURE; |
state change |
ZDHHC21 | REACTOME; |