| General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information | |
|---|---|
Gene ID | 4313 |
Name | MMP2 |
Synonymous | CLG4|CLG4A|MMP-II|MONA|TBE-1;matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase);MMP2;matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) |
Definition | 72 kDa gelatinase|72 kDa type IV collagenase|MMP-2|collagenase type IV-A|gelatinase A|matrix metalloproteinase-2|matrix metalloproteinase-II|neutrophil gelatinase |
Position | 16q13-q21 |
Gene Type | protein-coding |
Gene Interactions: | Physical Interaction Metabolic Interaction Signaling Interaction |
Physical Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
in same component |
ITGAM | NCI_NATURE; |
in same component |
ITGB2 | NCI_NATURE; |
in same component |
SDC2 | NCI_NATURE; |
interacts with |
A2M | BIOGRID; |
interacts with |
A2M | HPRD; |
interacts with |
ACAN | HPRD; |
interacts with |
BACE1 | HPRD; |
interacts with |
BCAN | BIOGRID; |
interacts with |
BCAN | HPRD; |
interacts with |
CCL7 | BIOGRID; |
interacts with |
CCL7 | HPRD; |
interacts with |
CLDN1 | HPRD; |
interacts with |
COL18A1 | HPRD; |
interacts with |
COL1A1 | BIOGRID; |
interacts with |
COL1A1 | HPRD; |
interacts with |
COL6A3 | HPRD; |
interacts with |
COL7A1 | HPRD; |
interacts with |
CXCL12 | HPRD; |
interacts with |
EPHB2 | HPRD; |
interacts with |
FGFR1 | HPRD; |
interacts with |
HAPLN1 | HPRD; |
interacts with |
HSP90AA1 | HPRD; |
interacts with |
IGFBP3 | HPRD; |
interacts with |
IL1B | HPRD; |
interacts with |
ITGAV | HPRD; |
interacts with |
KISS1 | HPRD; |
interacts with |
LCN2 | BIOGRID; |
interacts with |
LCN2 | HPRD; |
interacts with |
LGALS3 | HPRD; |
interacts with |
MMP14 | HPRD; |
interacts with |
MMP17 | HPRD; |
interacts with |
MMP25 | HPRD; |
interacts with |
OSBPL10 | BIOGRID; |
interacts with |
PLAU | NCI_NATURE; |
interacts with |
PZP | HPRD; |
interacts with |
SPOCK1 | HPRD; |
interacts with |
TGFB1 | BIOGRID; |
interacts with |
TGFB1 | HPRD; |
interacts with |
THBS1 | BIOGRID; |
interacts with |
THBS1 | HPRD; |
interacts with |
THBS2 | BIOGRID; |
interacts with |
THBS2 | HPRD; |
interacts with |
TIMP1 | HPRD; |
interacts with |
TIMP2 | BIOGRID; |
interacts with |
TIMP2 | HPRD; |
interacts with |
TIMP3 | BIOGRID; |
interacts with |
TIMP3 | HPRD; |
interacts with |
TIMP4 | BIOGRID; |
interacts with |
TIMP4 | HPRD; |
interacts with |
USP12 | BIOGRID; |
Metabolic Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
metabolic catalysis |
ATF2 | NCI_NATURE; |
metabolic catalysis |
CTNNB1 | NCI_NATURE; |
metabolic catalysis |
FOSL1 | NCI_NATURE; |
metabolic catalysis |
FOS | NCI_NATURE; |
metabolic catalysis |
JUNB | NCI_NATURE; |
metabolic catalysis |
JUN | NCI_NATURE; |
metabolic catalysis |
LEF1 | NCI_NATURE; |
metabolic catalysis |
LPAR1 | NCI_NATURE; |
metabolic catalysis |
TP53 | NCI_NATURE; |
Signaling Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
reacts with |
ITGAM | NCI_NATURE; |
reacts with |
ITGB2 | NCI_NATURE; |
reacts with |
MMP2 | NCI_NATURE; |
reacts with |
SDC2 | NCI_NATURE; |
state change |
ANGPT1 | NCI_NATURE; |
state change |
SRC | NCI_NATURE; |
state change |
TEK | NCI_NATURE; |