Entrez Gene

Pediatric cancer gene database (Pedican) Home

General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information
Gene ID	3082
Name	HGF
Synonymous	DFNB39\|F-TCF\|HGFB\|HPTA\|SF;hepatocyte growth factor (hepapoietin A; scatter factor);HGF;hepatocyte growth factor (hepapoietin A; scatter factor)
Definition	fibroblast-derived tumor cytotoxic factor\|hepatocyte growth factor\|hepatopoeitin-A\|hepatopoietin-A\|lung fibroblast-derived mitogen
Position	7q21.1
Gene Type	protein-coding
Gene Interactions:	Physical Interaction Metabolic Interaction Signaling Interaction

Interaction Type	Interactor	Data Source
Physical Interaction [Top]
in same component	CRK	NCI_NATURE;
in same component	CRKL	NCI_NATURE;
in same component	EPS15	NCI_NATURE;
in same component	GAB1	NCI_NATURE;
in same component	GAB2	NCI_NATURE;
in same component	INPP5D	NCI_NATURE;
in same component	INPPL1	NCI_NATURE;
in same component	MET	NCI_NATURE;
in same component	PAK4	NCI_NATURE;
in same component	PTPN11	NCI_NATURE;
in same component	RANBP10	NCI_NATURE;
in same component	RANBP9	NCI_NATURE;
in same component	SDC1	NCI_NATURE;
in same component	SOS1	NCI_NATURE;
in same component	WASL	NCI_NATURE;
interacts with	CLEC3B	BIOGRID;
interacts with	CLEC3B	HPRD;
interacts with	F11	HPRD;
interacts with	HGFAC	HPRD;
interacts with	Hgf	MINT;
interacts with	HPN	HPRD;
interacts with	KLKB1	HPRD;
interacts with	LCN2	HPRD;
interacts with	MET	BIOGRID;
interacts with	MET	HPRD;
interacts with	PLAU	NCI_NATURE;
interacts with	PLAUR	NCI_NATURE;
interacts with	SDC1	BIOGRID;
interacts with	SDC1	HPRD;
interacts with	SDC2	BIOGRID;
interacts with	SDC2	HPRD;
interacts with	ST14	HPRD;
interacts with	VTN	HPRD;

Interaction Type	Interactor	Data Source
Metabolic Interaction [Top]
metabolic catalysis	TP53	NCI_NATURE;

Interaction Type	Interactor	Data Source
Signaling Interaction [Top]
reacts with	CRK	NCI_NATURE;
reacts with	CRKL	NCI_NATURE;
reacts with	CTNNB1	NCI_NATURE;
reacts with	EPS15	NCI_NATURE;
reacts with	GAB1	NCI_NATURE;
reacts with	GAB2	NCI_NATURE;
reacts with	HGF	NCI_NATURE;
reacts with	INPP5D	NCI_NATURE;
reacts with	INPPL1	NCI_NATURE;
reacts with	MET	NCI_NATURE;
reacts with	PAK4	NCI_NATURE;
reacts with	PTPN11	NCI_NATURE;
reacts with	RANBP10	NCI_NATURE;
reacts with	RANBP9	NCI_NATURE;
reacts with	SDC1	NCI_NATURE;
reacts with	SOS1	NCI_NATURE;
reacts with	WASL	NCI_NATURE;
state change	CBL	NCI_NATURE;
state change	CDH1	NCI_NATURE;
state change	CTNNA1	NCI_NATURE;
state change	CTNNB1	NCI_NATURE;
state change	CTNND1	NCI_NATURE;
state change	GAB1	NCI_NATURE;
state change	HGF	NCI_NATURE;
state change	HGS	NCI_NATURE;
state change	KPNB1	NCI_NATURE;
state change	MET	NCI_NATURE;
state change	MUC20	NCI_NATURE;
state change	PLAU	NCI_NATURE;
state change	PLAUR	NCI_NATURE;
state change	PTPN11	NCI_NATURE;
state change	PTPN1	NCI_NATURE;
state change	PTPRJ	NCI_NATURE;
state change	SH3GL2	NCI_NATURE;
state change	SH3KBP1	NCI_NATURE;
state change	SRC	NCI_NATURE;

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