Entrez Gene

Pediatric cancer gene database (Pedican) Home

General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information
Gene ID	2736
Name	GLI2
Synonymous	HPE9\|THP1\|THP2;GLI family zinc finger 2;GLI2;GLI family zinc finger 2
Definition	GLI-Kruppel family member GLI2\|glioma-associated oncogene family zinc finger 2\|oncogene GLI2\|tax helper protein 1\|tax helper protein 2\|tax-responsive element-2 holding protein\|tax-responsive element-25-bp sequence binding protein\|zinc finger protein GLI2
Position	2q14
Gene Type	protein-coding
Gene Interactions:	Physical Interaction Metabolic Interaction Signaling Interaction

Interaction Type	Interactor	Data Source
Physical Interaction [Top]
in same component	SPOP	NCI_NATURE;
in same component	SUFU	NCI_NATURE;
interacts with	CREB1	BIOGRID;
interacts with	CREB1	HPRD;
interacts with	FBXW11	HPRD;
interacts with	HDAC1	BIOGRID;
interacts with	SKI	BIOGRID;
interacts with	SKI	HPRD;
interacts with	STK36	BIOGRID;
interacts with	STK36	HPRD;
interacts with	SUFU	BIOGRID;
interacts with	SUFU	HPRD;
interacts with	ZIC1	BIOGRID;
interacts with	ZIC1	HPRD;
interacts with	ZIC2	BIOGRID;
interacts with	ZIC2	HPRD;

Interaction Type	Interactor	Data Source
Metabolic Interaction [Top]
metabolic catalysis	AKT1	NCI_NATURE;
metabolic catalysis	ARRB2	NCI_NATURE;
metabolic catalysis	BTRC	NCI_NATURE;
metabolic catalysis	CDON	NCI_NATURE;
metabolic catalysis	IFT172	NCI_NATURE;
metabolic catalysis	IFT88	NCI_NATURE;
metabolic catalysis	KIF3A	NCI_NATURE;
metabolic catalysis	MAP2K1	NCI_NATURE;
metabolic catalysis	PRKCD	NCI_NATURE;
metabolic catalysis	RAB23	NCI_NATURE;
metabolic catalysis	SHH	NCI_NATURE;
metabolic catalysis	SMO	NCI_NATURE;

Interaction Type	Interactor	Data Source
Signaling Interaction [Top]
reacts with	GLI2	NCI_NATURE;
reacts with	SPOP	NCI_NATURE;
reacts with	SUFU	NCI_NATURE;
state change	ARRB2	NCI_NATURE;
state change	GSK3B	NCI_NATURE;
state change	PRKACA	NCI_NATURE;
state change	SMO	NCI_NATURE;
state change	STK36	NCI_NATURE;

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