| General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information | |
|---|---|
Gene ID | 860 |
Name | RUNX2 |
Synonym | AML3|CBFA1|CCD|CCD1|OSF-2|OSF2|PEA2aA|PEBP2A1|PEBP2A2|PEBP2aA|PEBP2aA1;runt-related transcription factor 2;RUNX2;runt-related transcription factor 2 |
Definition | CBF-alpha-1|PEA2-alpha A|PEBP2-alpha A|SL3-3 enhancer factor 1 alpha A subunit|SL3/AKV core-binding factor alpha A subunit|acute myeloid leukemia 3 protein|core-binding factor, runt domain, alpha subunit 1|oncogene AML-3|osteoblast-specific transcription |
Position | 6p21 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Regulation of retinoblastoma protein;PID Curated;200191 |
Pathway | Notch-mediated HES/HEY network;PID Curated;200196 |
Pathway | Regulation of nuclear SMAD2/3 signaling;PID Curated;200002 |
Pathway | FGF signaling pathway;PID Curated;200189 |
Disease | Bone Mineral Density;GAD |
Disease | Hereditary disease;FunDO |
Disease | bone density;GAD |
Disease | Dental anomalies, isolated;OMIM |
Disease | Bone disease;FunDO |
Disease | bone size;GAD |
Disease | Osteoporosis;FunDO |
Disease | Diabetes Mellitus, Type 2;GAD |
Disease | Cancer;FunDO |
Disease | METABOLIC;GAD |
Disease | Kidney failure;FunDO |
Disease | DEVELOPMENTAL;GAD |
Disease | height;GAD |
Disease | Cleidocranial dysplasia;OMIM |
External Links | |
Links to Entrez Gene | 860 |
Links to all GeneRIF Items | 860 |
Links to iHOP | 860 |
Sequence Information | |
Nucleotide Sequence | >860 : length: 1500 atggcatcaaacagcctcttcagcacagtgacaccatgtcagcaaaacttcttttgggat ccgagcaccagccggcgcttcagccccccctccagcagcctgcagcccggcaaaatgagc gacgtgagcccggtggtggctgcgcaacagcagcagcaacagcagcagcagcaacagcag cagcagcagcagcaacagcagcagcagcagcaggaggcggcggcggcggctgcggcggcg gcggcggctgcggcggcggcagctgcagtgccccggttgcggccgccccacgacaaccgc accatggtggagatcatcgccgaccacccggccgaactcgtccgcaccgacagccccaac ttcctgtgctcggtgctgccctcgcactggcgctgcaacaagaccctgcccgtggccttc aaggtggtagccctcggagaggtaccagatgggactgtggttactgtcatggcgggtaac gatgaaaattattctgctgagctccggaatgcctctgctgttatgaaaaaccaagtagca aggttcaacgatctgagatttgtgggccggagtggacgaggcaagagtttcaccttgacc ataaccgtcttcacaaatcctccccaagtagctacctatcacagagcaattaaagttaca gtagatggacctcgggaacccagaaggcacagacagaagcttgatgactctaaacctagt ttgttctctgaccgcctcagtgatttagggcgcattcctcatcccagtatgagagtaggt gtcccgcctcagaacccacggccctccctgaactctgcaccaagtccttttaatccacaa ggacagagtcagattacagaccccaggcaggcacagtcttccccgccgtggtcctatgac cagtcttacccctcctacctgagccagatgacgtccccgtccatccactctaccaccccg ctgtcttccacacggggcactgggcttcctgccatcaccgatgtgcctaggcgcatttca ggtgcttcagaactgggccctttttcagaccccaggcagttcccaagcatttcatccctc actgagagccgcttctccaacccacgaatgcactatccagccacctttacttacaccccg ccagtcacctcaggcatgtccctcggtatgtccgccaccactcactaccacacctacctg ccaccaccctaccccggctcttcccaaagccagagtggacccttccagaccagcagcact ccatatctctactatggcacttcgtcaggatcctatcagtttcccatggtgccgggggga gaccggtctccttccagaatgcttccgccatgcaccaccacctcgaatggcagcacgcta ttaaatccaaatttgcctaaccagaatgatggtgttgacgctgatggaagccacagcagt tccccaactgttttgaattctagtggcagaatggatgaatctgtttggcgaccatattga |
Protein Sequence | >860 : length: 499 MASNSLFSTVTPCQQNFFWDPSTSRRFSPPSSSLQPGKMSDVSPVVAAQQQQQQQQQQQQ QQQQQQQQQQQEAAAAAAAAAAAAAAAAAVPRLRPPHDNRTMVEIIADHPAELVRTDSPN FLCSVLPSHWRCNKTLPVAFKVVALGEVPDGTVVTVMAGNDENYSAELRNASAVMKNQVA RFNDLRFVGRSGRGKSFTLTITVFTNPPQVATYHRAIKVTVDGPREPRRHRQKLDDSKPS LFSDRLSDLGRIPHPSMRVGVPPQNPRPSLNSAPSPFNPQGQSQITDPRQAQSSPPWSYD QSYPSYLSQMTSPSIHSTTPLSSTRGTGLPAITDVPRRISGASELGPFSDPRQFPSISSL TESRFSNPRMHYPATFTYTPPVTSGMSLGMSATTHYHTYLPPPYPGSSQSQSGPFQTSST PYLYYGTSSGSYQFPMVPGGDRSPSRMLPPCTTTSNGSTLLNPNLPNQNDGVDADGSHSS SPTVLNSSGRMDESVWRPY |