| General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information | |
|---|---|
Gene ID | 79728 |
Name | PALB2 |
Synonym | FANCN|PNCA3;partner and localizer of BRCA2;PALB2;partner and localizer of BRCA2 |
Definition | - |
Position | 16p12.2 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Fanconi Anemia pathway;PID Reactome;500068 |
Pathway | DNA Repair;Reactome;REACT:216 |
Disease | Hematologic diseases;KEGG DISEASE |
Disease | PSYCH;GAD |
Disease | Fanconi's anemia;FunDO |
Disease | Prostate cancer;FunDO |
Disease | Primary tumor;FunDO |
Disease | Circulatory system diseases;KEGG DISEASE |
Disease | breast cancer;GAD |
Disease | Embryoma;FunDO |
Disease | Breast cancer, susceptibility to;OMIM |
Disease | CANCER;GAD |
Disease | Fanconi anemia, complementation group N;OMIM |
Disease | Bipolar disorder;NHGRI |
Disease | Fanconi anemia;KEGG DISEASE;H00238 |
Disease | bipolar disorder;GAD |
Disease | Breast cancer;FunDO |
Disease | Pancreatic cancer, susceptibility to, 3;OMIM |
External Links | |
Links to Entrez Gene | 79728 |
Links to all GeneRIF Items | 79728 |
Links to iHOP | 79728 |
Sequence Information | |
Nucleotide Sequence | >79728 : length: 3561 atggacgagcctcccgggaagcccctcagctgtgaggagaaggaaaagttaaaggagaaa ttagcattcttgaaaagggaatacagcaagacactagcccgccttcagcgtgcccaaaga gctgaaaagattaagcattctattaagaaaacagtagaagaacaagattgtttgtctcag caggatctctcaccgcagctaaaacactcagaacctaaaaataaaatatgtgtttatgac aagttacacatcaaaacccatcttgatgaagaaactggagaaaagacatctatcacactt gatgttgggcctgagtcctttaaccctggagatggcccaggaggattacctatacaaaga acagatgacacccaagaacattttccccacagggtcagtgaccctagtggtgagcaaaag cagaagctgccaagcagaagaaagaagcagcagaagaggacatttatttcacaggagaga gactgtgtctttggcactgattcactcagattgtctgggaaaagactaaaggaacaggaa gaaatcagtagcaaaaatcctgctagatcaccagtaactgaaataagaactcacctttta agtcttaaatctgaacttccagattctccagaaccagttacagaaattaatgaagacagt gtattaattccaccaactgcccaaccagaaaaaggtgttgatacattcctaagaagacct aatttcaccagggcgactacagttcctttacagactctatcagatagcggtagtagtcag caccttgaacacattcctcctaaaggtagcagtgaacttactactcacgacctaaaaaac attagatttacttcacctgtaagtttggaggcacaaggcaaaaaaatgactgtctctaca gataacctccttgtaaataaagctataagtaaaagtggccaactgcccacaagttctaat ttagaggcaaatatttcatgttctctaaatgaactcacctacaataacttaccagcaaat gaaaaccaaaacttaaaagaacaaaatcaaacagagaaatctttaaaatctcccagtgac actcttgatggcaggaatgaaaatcttcaggaaagtgagattctaagtcaacctaagagt cttagcctggaagcaacctctcctctttctgcagaaaaacattcttgcacagtgcctgaa ggccttctgtttcctgcagaatattatgttagaacaacacgaagcatgtccaattgccag aggaaagtagccgtggaggctgtcattcagagtcatttggatgtcaagaaaaaagggttt aaaaataaaaataaggatgcaagtaaaaatttaaacctttccaatgaggaaactgaccaa agtgaaattaggatgtctggcacatgcacaggacaaccaagttcaagaacctctcagaaa cttctctcattaactaaagtcagctctcccgctgggcccactgaagataatgacttgtct aggaaggcagttgcccaagcacctggtagaagatacacaggaaaaagaaaatcagcctgc accccagcatcagatcattgtgaaccacttttgccaacttctagcctgtcgattgttaac aggtccaaggaagaagtcacctcacacaaatatcagcacgaaaaattatttattcaagtg aaagggaagaaaagtcgtcatcaaaaagaggattccctttcttggagtaatagtgcttat ttatccttggatgatgatgctttcacggctccatttcatagggatggaatgctgagttta aagcaactactgtcttttctcagtatcacagactttcagttacctgatgaagactttgga cctcttaagcttgaaaaagtgaagtcctgctcagaaaaaccagtggagccctttgagtca aaaatgtttggagagagacatcttaaagagggaagctgtatttttccagaggaactgagt cctaaacgcatggatacagaaatggaggacttagaagaggaccttattgttctaccagga aaatcacatcccaaaaggccaaactcgcaaagccagcatacaaagacgggcctttcttca tccatattactttatactcctttaaatacggttgcgcctgatgataatgacaggcctacc acagacatgtgttcacctgctttccccatcttaggtactactccagcctttggccctcaa ggctcctatgaaaaagcatctacagaagttgctggacgaacttgctgcacaccccaactt gctcatttgaaagactcagtctgtcttgccagtgatactaaacaattcgacagttcaggc agcccagcaaaaccacataccaccctgcaagtgtcaggcaggcaaggacaacctacctgt gactgtgactctgtcccgccaggaacacctccacccattgagtcattcacttttaaagaa aatcagctctgtagaaacacatgccaggagctgcataaacattccgtcgaacagactgaa acagcagagcttcctgcttctgatagcataaacccaggcaacctacaattggtttcagag ttaaagaatccttcaggttcctgttccgtagatgtgagtgccatgttttgggaaagagcc ggttgtaaagagccatgtatcataactgcttgcgaagatgtagtttctctttggaaagct ctggatgcttggcagtgggaaaaactttatacctggcacttcgcagaggttccagtatta cagatagttccagtgcctgatgtgtataatctcgtgtgtgtagctttgggaaatttggaa atcagagagatcagggcattgttttgttcctctgatgatgaaagtgaaaagcaagtacta ctgaagtctggaaatataaaagctgtgcttggcctgacaaagaggaggctagttagtagc agtgggaccctttctgatcaacaagtagaagtcatgacgtttgcagaagatggaggaggc aaagaaaaccaatttttgatgccccctgaggagactatactaacttttgctgaggtccaa gggatgcaagaagctctgcttggtactactattatgaacaacattgttatttggaattta aaaactggtcaactcctgaaaaagatgcacattgatgattcttaccaagcttcagtctgt cacaaagcctattctgaaatggggcttctctttattgtcctgagtcatccctgtgccaaa gagagtgagtcgttgcgaagccctgtgtttcagctcattgtgattaaccctaagacgact ctcagcgtgggtgtgatgctgtactgtcttcctccagggcaggctggcaggttcctggaa ggtgacgtgaaagatcactgtgcagcagcaatcttgacttctggaacaattgccatttgg gacttacttctcggtcagtgtactgccctcctcccacctgtctctgaccaacattggtct tttgtgaaatggtcgggtacagactctcatttgctggctggacaaaaagatggaaatata tttgtataccactattcataa |
Protein Sequence | >79728 : length: 1186 MDEPPGKPLSCEEKEKLKEKLAFLKREYSKTLARLQRAQRAEKIKHSIKKTVEEQDCLSQ QDLSPQLKHSEPKNKICVYDKLHIKTHLDEETGEKTSITLDVGPESFNPGDGPGGLPIQR TDDTQEHFPHRVSDPSGEQKQKLPSRRKKQQKRTFISQERDCVFGTDSLRLSGKRLKEQE EISSKNPARSPVTEIRTHLLSLKSELPDSPEPVTEINEDSVLIPPTAQPEKGVDTFLRRP NFTRATTVPLQTLSDSGSSQHLEHIPPKGSSELTTHDLKNIRFTSPVSLEAQGKKMTVST DNLLVNKAISKSGQLPTSSNLEANISCSLNELTYNNLPANENQNLKEQNQTEKSLKSPSD TLDGRNENLQESEILSQPKSLSLEATSPLSAEKHSCTVPEGLLFPAEYYVRTTRSMSNCQ RKVAVEAVIQSHLDVKKKGFKNKNKDASKNLNLSNEETDQSEIRMSGTCTGQPSSRTSQK LLSLTKVSSPAGPTEDNDLSRKAVAQAPGRRYTGKRKSACTPASDHCEPLLPTSSLSIVN RSKEEVTSHKYQHEKLFIQVKGKKSRHQKEDSLSWSNSAYLSLDDDAFTAPFHRDGMLSL KQLLSFLSITDFQLPDEDFGPLKLEKVKSCSEKPVEPFESKMFGERHLKEGSCIFPEELS PKRMDTEMEDLEEDLIVLPGKSHPKRPNSQSQHTKTGLSSSILLYTPLNTVAPDDNDRPT TDMCSPAFPILGTTPAFGPQGSYEKASTEVAGRTCCTPQLAHLKDSVCLASDTKQFDSSG SPAKPHTTLQVSGRQGQPTCDCDSVPPGTPPPIESFTFKENQLCRNTCQELHKHSVEQTE TAELPASDSINPGNLQLVSELKNPSGSCSVDVSAMFWERAGCKEPCIITACEDVVSLWKA LDAWQWEKLYTWHFAEVPVLQIVPVPDVYNLVCVALGNLEIREIRALFCSSDDESEKQVL LKSGNIKAVLGLTKRRLVSSSGTLSDQQVEVMTFAEDGGGKENQFLMPPEETILTFAEVQ GMQEALLGTTIMNNIVIWNLKTGQLLKKMHIDDSYQASVCHKAYSEMGLLFIVLSHPCAK ESESLRSPVFQLIVINPKTTLSVGVMLYCLPPGQAGRFLEGDVKDHCAAAILTSGTIAIW DLLLGQCTALLPPVSDQHWSFVKWSGTDSHLLAGQKDGNIFVYHYS |