| General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information | |
|---|---|
Gene ID | 7345 |
Name | UCHL1 |
Synonym | PARK5|PGP 9.5|PGP9.5|PGP95|Uch-L1;ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase);UCHL1;ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) |
Definition | neuron cytoplasmic protein 9.5|ubiquitin C-terminal hydrolase|ubiquitin carboxyl-terminal hydrolase isozyme L1|ubiquitin thioesterase L1 |
Position | 4p14 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Alpha-synuclein signaling;PID Curated;200187 |
Pathway | Parkinson's disease;KEGG PATHWAY;hsa05012 |
Pathway | Parkinson disease;PANTHER;P00049 |
Disease | Parkinson's disease;KEGG DISEASE;H00057 |
Disease | Embryoma;FunDO |
Disease | Parkinson disease 5, susceptibility to;OMIM |
Disease | Renal Cell cancer;FunDO |
Disease | Alzheimer's disease;GAD |
Disease | Parkinson's disease;GAD |
Disease | Parkinson disease, resistance to;OMIM |
Disease | Lung cancer;FunDO |
Disease | Lysosomal storage disease;FunDO |
Disease | Nervous system diseases;KEGG DISEASE |
Disease | NEUROLOGICAL;GAD |
Disease | Neurodegenerative diseases;KEGG DISEASE |
Disease | Yersinia infection;FunDO |
Disease | Colon cancer;FunDO |
Disease | Alzheimer's disease;FunDO |
Disease | Huntington's disease;GAD |
Disease | Parkinson disease;FunDO |
External Links | |
Links to Entrez Gene | 7345 |
Links to all GeneRIF Items | 7345 |
Links to iHOP | 7345 |
Sequence Information | |
Nucleotide Sequence | >7345 : length: 672 atgcagctcaagccgatggagatcaaccccgagatgctgaacaaagtgctgtcccggctg ggggtcgccggccagtggcgcttcgtggacgtgctggggctggaagaggagtctctgggc tcggtgccagcgcctgcctgcgcgctgctgctgctgtttcccctcacggcccagcatgag aacttcaggaaaaagcagattgaagagctgaagggacaagaagttagtcctaaagtgtac ttcatgaagcagaccattgggaattcctgtggcacaatcggacttattcacgcagtggcc aataatcaagacaaactgggatttgaggatggatcagttctgaaacagtttctttctgaa acagagaaaatgtcccctgaagacagagcaaaatgctttgaaaagaatgaggccatacag gcagcccatgatgccgtggcacaggaaggccaatgtcgggtagatgacaaggtgaatttc cattttattctgtttaacaacgtggatggccacctctatgaacttgatggacgaatgcct tttccggtgaaccatggcgccagttcagaggacaccctgctgaaggacgctgccaaggtc tgcagagaattcaccgagcgtgagcaaggagaagtccgcttctctgccgtggctctctgc aaggcagcctaa |
Protein Sequence | >7345 : length: 223 MQLKPMEINPEMLNKVLSRLGVAGQWRFVDVLGLEEESLGSVPAPACALLLLFPLTAQHE NFRKKQIEELKGQEVSPKVYFMKQTIGNSCGTIGLIHAVANNQDKLGFEDGSVLKQFLSE TEKMSPEDRAKCFEKNEAIQAAHDAVAQEGQCRVDDKVNFHFILFNNVDGHLYELDGRMP FPVNHGASSEDTLLKDAAKVCREFTEREQGEVRFSAVALCKAA |