| General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information | |
|---|---|
Gene ID | 6929 |
Name | TCF3 |
Synonym | E2A|E47|ITF1|TCF-3|VDIR|bHLHb21;transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47);TCF3;transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) |
Definition | VDR interacting repressor|class B basic helix-loop-helix protein 21|helix-loop-helix protein HE47|immunoglobulin transcription factor 1|kappa-E2-binding factor|negative vitamin D response element-binding protein|transcription factor E2-alpha|transcription |
Position | 19p13.3 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Notch-mediated HES/HEY network;PID Curated;200196 |
Pathway | p38 signaling mediated by MAPKAP kinases;PID Curated;200135 |
Pathway | Myogenesis;Reactome;REACT:21303 |
Pathway | Regulation of nuclear SMAD2/3 signaling;PID Curated;200002 |
Disease | Leukemia, acute lymphoblastic;OMIM |
Disease | Acute lymphoblastic leukemia (ALL) (Precursor B lymphoblastic leukemia);KEGG DISEASE;H00001 |
Disease | Cancers;KEGG DISEASE |
Disease | Cancers of haematopoietic and lymphoid tissues;KEGG DISEASE |
External Links | |
Links to Entrez Gene | 6929 |
Links to all GeneRIF Items | 6929 |
Links to iHOP | 6929 |
Sequence Information | |
Nucleotide Sequence | >6929 : length: 1956 atgaaccagccgcagaggatggcgcctgtgggcacagacaaggagctcagtgacctcctg gacttcagcatgatgttcccgctgcctgtcaccaacgggaagggccggcccgcctccctg gccggggcgcagttcggaggttcaggtcttgaggaccggcccagctcaggctcctggggc agcggcgaccagagcagctcctcctttgaccccagccggaccttcagcgagggcacccac ttcactgagtcgcacagcagcctctcttcatccacattcctgggaccgggactcggaggc aagagcggtgagcggggcgcctatgcctccttcgggagagacgcaggcgtgggcggcctg actcaggctggcttcctgtcaggcgagctggccctcaacagccccgggcccctgtcccct tcgggcatgaaggggacctcccagtactacccctcctactccggcagctcccggcggaga gcggcagacggcagcctagacacgcagcccaagaaggtccggaaggtcccgccgggtctt ccatcctcggtgtacccacccagctcaggtgaggactacggcagggatgccaccgcctac ccgtccgccaagacccccagcagcacctatcccgcccccttctacgtggcagatggcagc ctgcacccctcagccgagctctggagtcccccgggccaggcgggcttcgggcccatgctg ggtgggggctcatccccgctgcccctcccgcccggtagcggcccggtgggcagcagtgga agcagcagcacgtttggtggcctgcaccagcacgagcgtatgggctaccagctgcatgga gcagaggtgaacggtgggctcccatctgcatcctccttctcctcagcccccggagccacg tacggcggcgtctccagccacacgccgcctgtcagcggggccgacagcctcctgggctcc cgagggaccacagctggcagctccggggatgccctcggcaaagcactggcctcgatctac tccccggatcactcaagcaataacttctcgtccagcccttctacccccgtgggctccccc cagggcctggcaggaacgtcacagtggcctcgagcaggagcccccggtgccttatcgccc agctacgacgggggtctccacggcctgcagagtaagatagaagaccacctggacgaggcc atccacgtgctccgcagccacgccgtgggcacagccggcgacatgcacacgctgctgcct ggccacggggcgctggcctcaggtttcaccggccccatgtcactgggcgggcggcacgca ggcctggttggaggcagccaccccgaggacggcctcgcaggcagcaccagcctcatgcac aaccacgcggccctccccagccagccaggcaccctccctgacctgtctcggcctcccgac tcctacagtgggctagggcgagcaggtgccacggcggccgccagcgagatcaagcgggag gagaaggaggacgaggagaacacgtcagcggctgaccactcggaggaggagaagaaggag ctgaaggccccccgggcccggaccagcagtacggacgaggtgctgtccctggaggagaaa gacctgagggaccgggagaggcgcatggccaataacgcgcgggagcgggtgcgcgtgcgg gatattaacgaggccttccgggagctggggcgcatgtgccagatgcacctcaagtcggac aaagcgcagaccaagctgctcatcctgcagcaggccgtgcaggtcatcctggggctggag cagcaggtgcgagagcggaacctgaatcccaaagcagcctgtttgaaacggcgagaagag gaaaaggtgtcaggtgtggttggagacccccagatggtgctttcagctccccacccaggc ctgagcgaagcccacaaccccgccgggcacatgtga |
Protein Sequence | >6929 : length: 651 MNQPQRMAPVGTDKELSDLLDFSMMFPLPVTNGKGRPASLAGAQFGGSGLEDRPSSGSWG SGDQSSSSFDPSRTFSEGTHFTESHSSLSSSTFLGPGLGGKSGERGAYASFGRDAGVGGL TQAGFLSGELALNSPGPLSPSGMKGTSQYYPSYSGSSRRRAADGSLDTQPKKVRKVPPGL PSSVYPPSSGEDYGRDATAYPSAKTPSSTYPAPFYVADGSLHPSAELWSPPGQAGFGPML GGGSSPLPLPPGSGPVGSSGSSSTFGGLHQHERMGYQLHGAEVNGGLPSASSFSSAPGAT YGGVSSHTPPVSGADSLLGSRGTTAGSSGDALGKALASIYSPDHSSNNFSSSPSTPVGSP QGLAGTSQWPRAGAPGALSPSYDGGLHGLQSKIEDHLDEAIHVLRSHAVGTAGDMHTLLP GHGALASGFTGPMSLGGRHAGLVGGSHPEDGLAGSTSLMHNHAALPSQPGTLPDLSRPPD SYSGLGRAGATAAASEIKREEKEDEENTSAADHSEEEKKELKAPRARTSSTDEVLSLEEK DLRDRERRMANNARERVRVRDINEAFRELGRMCQMHLKSDKAQTKLLILQQAVQVILGLE QQVRERNLNPKAACLKRREEEKVSGVVGDPQMVLSAPHPGLSEAHNPAGHM |