Pediatric cancer gene database (Pedican) Home
Pedican
Pediatric cancer database
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

6556

Name

SLC11A1

Synonym

LSH|NRAMP|NRAMP1;solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1;SLC11A1;solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1

Definition

NRAMP 1|natural resistance-associated macrophage protein 1|solute carrier family 11 (sodium/phosphate symporters), member 1

Position

2q35

Gene Type

protein-coding

Pathways and Diseases

Pathway

Validated targets of C-MYC transcriptional repression;PID Curated;200171

Pathway

Lysosome;KEGG PATHWAY;hsa04142

Pathway

Metal ion SLC transporters;PID Reactome;500353

Pathway

Transmembrane transport of small molecules;Reactome;REACT:15518

Disease

IMMUNE;GAD

Disease

inflammatory bowel disease;GAD

Disease

Mycobacterium infection, Atypical;FunDO

Disease

Mycobacterium tuberculosis, susceptibility to infection by;OMIM

Disease

susceptibility to tuberculosis;GAD

Disease

Asthma;FunDO

Disease

esophageal cancer;GAD

Disease

Mucocutaneous lymph node syndrome;FunDO

Disease

Embryoma;FunDO

Disease

Leprosy;FunDO

Disease

Anemia;FunDO

Disease

Systemic scleroderma;FunDO

Disease

Behcet Syndrome;GAD

Disease

rheumatoid arthritis;GAD

Disease

INFECTION;GAD

Disease

Autoimmune disease;FunDO

Disease

tuberculosis;GAD

Disease

Tuberculosis;FunDO

Disease

diabetes, type 1;GAD

Disease

microscopy-positive tuberculosis;GAD

Disease

Esophageal tumor;FunDO

Disease

CANCER;GAD

Disease

Crohn's disease;GAD

Disease

Brucellosis;FunDO

Disease

Chronic obstructive airway disease;FunDO

Disease

Behcet syndrome;FunDO

Disease

Buruli ulcer, susceptibility to;OMIM

Disease

Enteritis;FunDO

Disease

Spondylarthropathies;FunDO

Disease

ulcerative colitis;GAD

Disease

Arthritis;FunDO

External Links

Links to Entrez Gene

6556

Links to all GeneRIF Items

6556

Links to iHOP

6556

Sequence Information

Nucleotide Sequence

>6556 : length: 1653
atgacaggtgacaagggtccccaaaggctaagcgggtccagctatggttccatctccagc
ccgaccagcccgaccagcccagggccacagcaagcacctcccagagagacctacctgagt
gagaagatccccatcccagacacaaaaccgggcaccttcagcctgcggaagctatgggcc
ttcacggggcctggcttcctcatgagcattgctttcctggacccaggaaacatcgagtca
gatcttcaggctggcgccgtggcgggattcaaacttctctgggtgctgctctgggccacc
gtgttgggcttgctctgccagcgactggctgcacgtctgggcgtggtgacaggcaaggac
ttgggcgaggtctgccatctctactaccctaaggtgccccgcaccgtcctctggctgacc
atcgagctagccattgtgggctccgacatgcaggaagtcatcggcacggccattgcattc
aatctgctctcagctggacgaatcccactctggggtggcgtcctcatcaccatcgtggac
accttcttcttcctcttcctcgataactacgggctgcggaagctggaagctttttttgga
ctccttataaccattatggccttgacctttggctatgagtatgtggtggcgcgtcctgag
cagggagcgcttcttcggggcctgttcctgccctcgtgcccgggctgcggccaccccgag
ctgctgcaggcggtgggcattgttggcgccatcatcatgccccacaacatctacctgcac
tcggccctggtcaagtctcgagagatagaccgggcccgccgagcagacatcagagaagcc
aacatgtacttcctgattgaggccaccatcgccctgtccgtctcctttatcatcaacctc
tttgtcatggctgtctttgggcaggccttctaccagaaaaccaaccaggctgcgttcaac
atctgtgccaacagcagcctccacgactacgccaagatcttccccatgaacaacgccacc
gtggccgtggacatttaccaggggggcgtgatcctgggctgcctgttcggccccgcggcc
ctctacatctgggccataggtctcctggcggctgggcagagctccaccatgacgggcacc
tacgcgggacagttcgtgatggagggcttcctgaggctgcggtggtcacgcttcgcccgt
gtcctcctcacccgctcctgcgccatcctgcccaccgtgctcgtggctgtcttccgggac
ctgagggacttgtcgggcctcaatgatctgctcaacgtgctgcagagcctgctgctcccg
ttcgccgtgctgcccatcctcacgttcaccagcatgcccaccctcatgcaggagtttgcc
aatggcctgctgaacaaggtcgtcacctcttccatcatggtgctagtctgcgccatcaac
ctctacttcgtggtcagctatctgcccagcctgccccaccctgcctacttcggccttgca
gccttgctggccgcagcctacctgggcctcagcacctacctggtctggacctgttgcctt
gcccacggagccacctttctggcccacagctcccaccaccacttcctgtatgggctcctt
gaagaggaccagaaaggggagacctctggctag

Protein Sequence

>6556 : length: 550
MTGDKGPQRLSGSSYGSISSPTSPTSPGPQQAPPRETYLSEKIPIPDTKPGTFSLRKLWA
FTGPGFLMSIAFLDPGNIESDLQAGAVAGFKLLWVLLWATVLGLLCQRLAARLGVVTGKD
LGEVCHLYYPKVPRTVLWLTIELAIVGSDMQEVIGTAIAFNLLSAGRIPLWGGVLITIVD
TFFFLFLDNYGLRKLEAFFGLLITIMALTFGYEYVVARPEQGALLRGLFLPSCPGCGHPE
LLQAVGIVGAIIMPHNIYLHSALVKSREIDRARRADIREANMYFLIEATIALSVSFIINL
FVMAVFGQAFYQKTNQAAFNICANSSLHDYAKIFPMNNATVAVDIYQGGVILGCLFGPAA
LYIWAIGLLAAGQSSTMTGTYAGQFVMEGFLRLRWSRFARVLLTRSCAILPTVLVAVFRD
LRDLSGLNDLLNVLQSLLLPFAVLPILTFTSMPTLMQEFANGLLNKVVTSSIMVLVCAIN
LYFVVSYLPSLPHPAYFGLAALLAAAYLGLSTYLVWTCCLAHGATFLAHSSHHHFLYGLL
EEDQKGETSG



')