| General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information | |
|---|---|
Gene ID | 578 |
Name | BAK1 |
Synonym | BAK|BAK-LIKE|BCL2L7|CDN1;BCL2-antagonist/killer 1;BAK1;BCL2-antagonist/killer 1 |
Definition | BCL2-like 7 protein|apoptosis regulator BAK|bcl-2 homologous antagonist/killer|bcl-2-like protein 7|bcl2-L-7|pro-apoptotic protein BAK |
Position | 6p21.3 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Apoptosis;Reactome;REACT:578 |
Pathway | Activation and oligomerization of BAK protein;PID Reactome;501018 |
Pathway | Direct p53 effectors;PID Curated;200101 |
Pathway | role of mitochondria in apoptotic signaling;PID BioCarta;100106 |
Pathway | Apoptosis signaling pathway;PANTHER;P00006 |
Pathway | Protein processing in endoplasmic reticulum;KEGG PATHWAY;hsa04141 |
Disease | Autoimmune disease;FunDO |
Disease | Testicular germ cell tumor;NHGRI |
Disease | Squamous cell cancer;FunDO |
Disease | Fibroid tumor;FunDO |
Disease | HEMATOLOGICAL;GAD |
Disease | Thyroid gland disease;FunDO |
Disease | Celiac disease;FunDO |
Disease | hematological parameters;GAD |
Disease | Melanoma;FunDO |
Disease | testicular germ cell tumor;GAD |
Disease | Dental plaque;FunDO |
Disease | Hematological parameters;NHGRI |
Disease | CANCER;GAD |
Disease | Vaccinia;FunDO |
Disease | Breast cancer;FunDO |
Disease | Stomach cancer;FunDO |
Disease | Glaucoma;FunDO |
External Links | |
Links to Entrez Gene | 578 |
Links to all GeneRIF Items | 578 |
Links to iHOP | 578 |
Sequence Information | |
Nucleotide Sequence | >578 : length: 636 atggcttcggggcaaggcccaggtcctcccaggcaggagtgcggagagcctgccctgccc tctgcttctgaggagcaggtagcccaggacacagaggaggttttccgcagctacgttttt taccgccatcagcaggaacaggaggctgaaggggtggctgcccctgccgacccagagatg gtcaccttacctctgcaacctagcagcaccatggggcaggtgggacggcagctcgccatc atcggggacgacatcaaccgacgctatgactcagagttccagaccatgttgcagcacctg cagcccacggcagagaatgcctatgagtacttcaccaagattgccaccagcctgtttgag agtggcatcaattggggccgtgtggtggctcttctgggcttcggctaccgtctggcccta cacgtctaccagcatggcctgactggcttcctaggccaggtgacccgcttcgtggtcgac ttcatgctgcatcactgcattgcccggtggattgcacagaggggtggctgggtggcagcc ctgaacttgggcaatggtcccatcctgaacgtgctggtggttctgggtgtggttctgttg ggccagtttgtggtacgaagattcttcaaatcatga |
Protein Sequence | >578 : length: 211 MASGQGPGPPRQECGEPALPSASEEQVAQDTEEVFRSYVFYRHQQEQEAEGVAAPADPEM VTLPLQPSSTMGQVGRQLAIIGDDINRRYDSEFQTMLQHLQPTAENAYEYFTKIATSLFE SGINWGRVVALLGFGYRLALHVYQHGLTGFLGQVTRFVVDFMLHHCIARWIAQRGGWVAA LNLGNGPILNVLVVLGVVLLGQFVVRRFFKS |