| General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information | |
|---|---|
Gene ID | 55294 |
Name | FBXW7 |
Synonym | AGO|CDC4|FBW6|FBW7|FBX30|FBXO30|FBXW6|SEL-10|SEL10;F-box and WD repeat domain containing 7;FBXW7;F-box and WD repeat domain containing 7 |
Definition | F-box and WD-40 domain protein 7 (archipelago homolog, Drosophila)|F-box protein FBW7|F-box protein FBX30|F-box protein SEL-10|F-box/WD repeat-containing protein 7|hAgo|hCdc4|homolog of C elegans sel-10 |
Position | 4q31.3 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Notch signaling pathway;PANTHER;P00045 |
Pathway | Metabolism of proteins;Reactome;REACT:17015 |
Pathway | Ubiquitin mediated proteolysis;KEGG PATHWAY;hsa04120 |
Pathway | C-MYC pathway;PID Curated;200093 |
External Links | |
Links to Entrez Gene | 55294 |
Links to all GeneRIF Items | 55294 |
Links to iHOP | 55294 |
Sequence Information | |
Nucleotide Sequence | >55294 : length: 1770 atgtcaaaaccgggaaaacctactctaaaccatggcttggttcctgttgatcttaaaagt gcaaaagagcctctaccacatcaaactgtgatgaagatatttagcattagcatcattgcc caaggcctccctttttgtcgaagacggatgaaaagaaagttggaccatggttctgaggtc cgctctttttctttgggaaagaaaccatgcaaagtctcagaatatacaagtaccactggg cttgtaccatgttcagcaacaccaacaacttttggggacctcagagcagccaatggccaa gggcaacaacgacgccgaattacatctgtccagccacctacaggcctccaggaatggcta aaaatgtttcagagctggagtggaccagagaaattgcttgctttagatgaactcattgat agttgtgaaccaacacaagtaaaacatatgatgcaagtgatagaaccccagtttcaacga gacttcatttcattgctccctaaagagttggcactctatgtgctttcattcctggaaccc aaagacctgctacaagcagctcagacatgtcgctactggagaattttggctgaagacaac cttctctggagagagaaatgcaaagaagaggggattgatgaaccattgcacatcaagaga agaaaagtaataaaaccaggtttcatacacagtccatggaaaagtgcatacatcagacag cacagaattgatactaactggaggcgaggagaactcaaatctcctaaggtgctgaaagga catgatgatcatgtgatcacatgcttacagttttgtggtaaccgaatagttagtggttct gatgacaacactttaaaagtttggtcagcagtcacaggcaaatgtctgagaacattagtg ggacatacaggtggagtatggtcatcacaaatgagagacaacatcatcattagtggatct acagatcggacactcaaagtgtggaatgcagagactggagaatgtatacacaccttatat gggcatacttccactgtgcgttgtatgcatcttcatgaaaaaagagttgttagcggttct cgagatgccactcttagggtttgggatattgagacaggccagtgtttacatgttttgatg ggtcatgttgcagcagtccgctgtgttcaatatgatggcaggagggttgttagtggagca tatgattttatggtaaaggtgtgggatccagagactgaaacctgtctacacacgttgcag gggcatactaatagagtctattcattacagtttgatggtatccatgtggtgagtggatct cttgatacatcaatccgtgtttgggatgtggagacagggaattgcattcacacgttaaca gggcaccagtcgttaacaagtggaatggaactcaaagacaatattcttgtctctgggaat gcagattctacagttaaaatctgggatatcaaaacaggacagtgtttacaaacattgcaa ggtcccaacaagcatcagagtgctgtgacctgtttacagttcaacaagaactttgtaatt accagctcagatgatggaactgtaaaactatgggacttgaaaacgggtgaatttattcga aacctagtcacattggagagtggggggagtgggggagttgtgtggcggatcagagcctca aacacaaagctggtgtgtgcagttgggagtcggaatgggactgaagaaaccaagctgctg gtgctggactttgatgtggacatgaagtga |
Protein Sequence | >55294 : length: 589 MSKPGKPTLNHGLVPVDLKSAKEPLPHQTVMKIFSISIIAQGLPFCRRRMKRKLDHGSEV RSFSLGKKPCKVSEYTSTTGLVPCSATPTTFGDLRAANGQGQQRRRITSVQPPTGLQEWL KMFQSWSGPEKLLALDELIDSCEPTQVKHMMQVIEPQFQRDFISLLPKELALYVLSFLEP KDLLQAAQTCRYWRILAEDNLLWREKCKEEGIDEPLHIKRRKVIKPGFIHSPWKSAYIRQ HRIDTNWRRGELKSPKVLKGHDDHVITCLQFCGNRIVSGSDDNTLKVWSAVTGKCLRTLV GHTGGVWSSQMRDNIIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHLHEKRVVSGS RDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGRRVVSGAYDFMVKVWDPETETCLHTLQ GHTNRVYSLQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKDNILVSGN ADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKNFVITSSDDGTVKLWDLKTGEFIR NLVTLESGGSGGVVWRIRASNTKLVCAVGSRNGTEETKLLVLDFDVDMK |