| General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information | |
|---|---|
Gene ID | 5395 |
Name | PMS2 |
Synonym | HNPCC4|PMS2CL|PMSL2;PMS2 postmeiotic segregation increased 2 (S. cerevisiae);PMS2;PMS2 postmeiotic segregation increased 2 (S. cerevisiae) |
Definition | DNA mismatch repair protein PMS2|H_DJ0042M02.9|PMS1 protein homolog 2|mismatch repair endonuclease PMS2 |
Position | 7p22.2 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Mismatch repair;KEGG PATHWAY;hsa03430 |
Pathway | Direct p53 effectors;PID Curated;200101 |
Disease | Hyperaldosteronism;FunDO |
Disease | Cancer;FunDO |
Disease | Mismatch repair cancer syndrome;OMIM |
Disease | Colorectal cancer, hereditary nonpolyposis, type 4;OMIM |
External Links | |
Links to Entrez Gene | 5395 |
Links to all GeneRIF Items | 5395 |
Links to iHOP | 5395 |
Sequence Information | |
Nucleotide Sequence | >5395 : length: 2589 atggagcgagctgagagctcgagtacagaacctgctaaggccatcaaacctattgatcgg aagtcagtccatcagatttgctctgggcaggtggtactgagtctaagcactgcggtaaag gagttagtagaaaacagtctggatgctggtgccactaatattgatctaaagcttaaggac tatggagtggatcttattgaagtttcagacaatggatgtggggtagaagaagaaaacttc gaaggcttaactctgaaacatcacacatctaagattcaagagtttgccgacctaactcag gttgaaacttttggctttcggggggaagctctgagctcactttgtgcactgagcgatgtc accatttctacctgccacgcatcggcgaaggttggaactcgactgatgtttgatcacaat gggaaaattatccagaaaaccccctacccccgccccagagggaccacagtcagcgtgcag cagttattttccacactacctgtgcgccataaggaatttcaaaggaatattaagaaggag tatgccaaaatggtccaggtcttacatgcatactgtatcatttcagcaggcatccgtgta agttgcaccaatcagcttggacaaggaaaacgacagcctgtggtatgcacaggtggaagc cccagcataaaggaaaatatcggctctgtgtttgggcagaagcagttgcaaagcctcatt ccttttgttcagctgccccctagtgactccgtgtgtgaagagtacggtttgagctgttcc gatgctctgcataatcttttttacatctcaggtttcatttcacaatgcacgcatggagtt ggaaggagttcaacagacagacagtttttctttatcaaccggcggccttgtgacccagca aaggtctgcagactcgtgaatgaggtctaccacatgtataatcgacaccagtatccattt gttgttcttaacatttctgttgattcagaatgcgttgatatcaatgttactccagataaa aggcaaattttgctacaagaggaaaagcttttgttggcagttttaaagacctctttgata ggaatgtttgatagtgatgtcaacaagctaaatgtcagtcagcagccactgctggatgtt gaaggtaacttaataaaaatgcatgcagcggatttggaaaagcccatggtagaaaagcag gatcaatccccttcattaaggactggagaagaaaaaaaagacgtgtccatttccagactg cgagaggccttttctcttcgtcacacaacagagaacaagcctcacagcccaaagactcca gaaccaagaaggagccctctaggacagaaaaggggtatgctgtcttctagcacttcaggt gccatctctgacaaaggcgtcctgagacctcagaaagaggcagtgagttccagtcacgga cccagtgaccctacggacagagcggaggtggagaaggactcggggcacggcagcacttcc gtggattctgaggggttcagcatcccagacacgggcagtcactgcagcagcgagtatgcg gccagctccccaggggacaggggctcgcaggaacatgtggactctcaggagaaagcgcct gaaactgacgactctttttcagatgtggactgccattcaaaccaggaagataccggatgt aaatttcgagttttgcctcagccaactaatctcgcaaccccaaacacaaagcgttttaaa aaagaagaaattctttccagttctgacatttgtcaaaagttagtaaatactcaggacatg tcagcctctcaggttgatgtagctgtgaaaattaataagaaagttgtgcccctggacttt tctatgagttctttagctaaacgaataaagcagttacatcatgaagcacagcaaagtgaa ggggaacagaattacaggaagtttagggcaaagatttgtcctggagaaaatcaagcagcc gaagatgaactaagaaaagagataagtaaaacgatgtttgcagaaatggaaatcattggt cagtttaacctgggatttataataaccaaactgaatgaggatatcttcatagtggaccag catgccacggacgagaagtataacttcgagatgctgcagcagcacaccgtgctccagggg cagaggctcatagcacctcagactctcaacttaactgctgttaatgaagctgttctgata gaaaatctggaaatatttagaaagaatggctttgattttgttatcgatgaaaatgctcca gtcactgaaagggctaaactgatttccttgccaactagtaaaaactggaccttcggaccc caggacgtcgatgaactgatcttcatgctgagcgacagccctggggtcatgtgccggcct tcccgagtcaagcagatgtttgcctccagagcctgccggaagtcggtgatgattgggact gctcttaacacaagcgagatgaagaaactgatcacccacatgggggagatggaccacccc tggaactgtccccatggaaggccaaccatgagacacatcgccaacctgggtgtcatttct cagaactga |
Protein Sequence | >5395 : length: 862 MERAESSSTEPAKAIKPIDRKSVHQICSGQVVLSLSTAVKELVENSLDAGATNIDLKLKD YGVDLIEVSDNGCGVEEENFEGLTLKHHTSKIQEFADLTQVETFGFRGEALSSLCALSDV TISTCHASAKVGTRLMFDHNGKIIQKTPYPRPRGTTVSVQQLFSTLPVRHKEFQRNIKKE YAKMVQVLHAYCIISAGIRVSCTNQLGQGKRQPVVCTGGSPSIKENIGSVFGQKQLQSLI PFVQLPPSDSVCEEYGLSCSDALHNLFYISGFISQCTHGVGRSSTDRQFFFINRRPCDPA KVCRLVNEVYHMYNRHQYPFVVLNISVDSECVDINVTPDKRQILLQEEKLLLAVLKTSLI GMFDSDVNKLNVSQQPLLDVEGNLIKMHAADLEKPMVEKQDQSPSLRTGEEKKDVSISRL REAFSLRHTTENKPHSPKTPEPRRSPLGQKRGMLSSSTSGAISDKGVLRPQKEAVSSSHG PSDPTDRAEVEKDSGHGSTSVDSEGFSIPDTGSHCSSEYAASSPGDRGSQEHVDSQEKAP ETDDSFSDVDCHSNQEDTGCKFRVLPQPTNLATPNTKRFKKEEILSSSDICQKLVNTQDM SASQVDVAVKINKKVVPLDFSMSSLAKRIKQLHHEAQQSEGEQNYRKFRAKICPGENQAA EDELRKEISKTMFAEMEIIGQFNLGFIITKLNEDIFIVDQHATDEKYNFEMLQQHTVLQG QRLIAPQTLNLTAVNEAVLIENLEIFRKNGFDFVIDENAPVTERAKLISLPTSKNWTFGP QDVDELIFMLSDSPGVMCRPSRVKQMFASRACRKSVMIGTALNTSEMKKLITHMGEMDHP WNCPHGRPTMRHIANLGVISQN |