| General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information | |
|---|---|
Gene ID | 4353 |
Name | MPO |
Synonym | -;myeloperoxidase;MPO;myeloperoxidase |
Definition | - |
Position | 17q23.1 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | IL23-mediated signaling events;PID Curated;200131 |
Pathway | C-MYB transcription factor network;PID Curated;200130 |
Pathway | Phagosome;KEGG PATHWAY;hsa04145 |
Pathway | eicosanoid metabolism;PID BioCarta;100180 |
Disease | Ischemia;FunDO |
Disease | Vasculitis;FunDO |
Disease | liver disease;GAD |
Disease | breast cancer;GAD |
Disease | Alzheimer's disease;GAD |
Disease | Lung cancer;FunDO |
Disease | Periodontitis;FunDO |
Disease | Myeloperoxidase deficiency;OMIM |
Disease | reduced risk of lung cancer;GAD |
Disease | bladder cancer;GAD |
Disease | Breast cancer;FunDO |
Disease | AGING;GAD |
Disease | cirrhosis;GAD |
Disease | Helicobacter infection;FunDO |
Disease | breast cancer survival;GAD |
Disease | genetic polymorphism;GAD |
Disease | coronary vasculopathy;GAD |
Disease | Kidney Failure, Chronic;GAD |
Disease | hepatitis C;GAD |
Disease | Prostate cancer;FunDO |
Disease | lung cancer;GAD |
Disease | IMMUNE;GAD |
Disease | myeloperoxidase activity;GAD |
Disease | cardiovascular disease;GAD |
Disease | gastric disease;GAD |
Disease | Leukemia;FunDO |
Disease | PHARMACOGENOMIC;GAD |
Disease | MPO -463 A allele;GAD |
Disease | Systemic infection;FunDO |
Disease | METABOLIC;GAD |
Disease | cognitive decline;GAD |
Disease | Pancreas cancer;FunDO |
Disease | Alzheimer disease, susceptibility to;OMIM |
Disease | benzene toxicity;GAD |
Disease | lung cancer risk;GAD |
Disease | Cervical cancer;FunDO |
Disease | cardiac death cardiovascular disease oxidative stress;GAD |
Disease | Periodontal disease;FunDO |
Disease | esophageal cancer;GAD |
Disease | Diabetes mellitus;FunDO |
Disease | gastritis, Helicobacter pylori-induced;GAD |
Disease | Hepatoblastoma;FunDO |
Disease | Coronary Artery Disease;GAD |
Disease | CARDIOVASCULAR;GAD |
Disease | Other phagocyte defects;KEGG DISEASE;H00101 |
Disease | Multiple sclerosis;FunDO |
Disease | Stroke;FunDO |
Disease | Glomerulonephritis;FunDO |
Disease | antibodies-associated small vessel;GAD |
Disease | Kidney failure;FunDO |
Disease | Sickle cell disease;FunDO |
Disease | Primary immunodeficiency;KEGG DISEASE |
Disease | INFECTION;GAD |
Disease | NEUROLOGICAL;GAD |
Disease | lung squamous cell carcinoma;GAD |
Disease | Stomach disease;FunDO |
Disease | Helicobacter pylori infection;GAD |
Disease | Duodenal Ulcer;GAD |
Disease | periodontal disease;GAD |
Disease | Hyperlipidemia;FunDO |
Disease | vasculitis, antineutrophil cytoplasmic;GAD |
Disease | Alzheimer's disease;FunDO |
Disease | cerebral infarct;GAD |
Disease | Immune system diseases;KEGG DISEASE |
Disease | CANCER;GAD |
Disease | Lung cancer, protection against, in smokers;OMIM |
Disease | DNA adducts;GAD |
Disease | multiple sclerosis;GAD |
Disease | Atherosclerosis;GAD |
Disease | gastric atrophy gastric disease;GAD |
Disease | RENAL;GAD |
Disease | stomach cancer;GAD |
Disease | Atherosclerosis;FunDO |
External Links | |
Links to Entrez Gene | 4353 |
Links to all GeneRIF Items | 4353 |
Links to iHOP | 4353 |
Sequence Information | |
Nucleotide Sequence | >4353 : length: 2238 atgggggttcccttcttctcttctctcagatgcatggtggacttaggaccttgctgggct gggggtctcactgcagagatgaagctgcttctggccctagcagggctcctggccattctg gccacgccccagccctctgaaggtgctgctccagctgtcctgggggaggtggacacctcg ttggtgctgagctccatggaggaggccaagcagctggtggacaaggcctacaaggagcgg cgggaaagcatcaagcagcggcttcgcagcggctcagccagccccatggaactcctatcc tacttcaagcagccggtggcagccaccaggacggcggtgagggccgctgactacctgcac gtggctctagacctgctggagaggaagctgcggtccctgtggcgaaggccattcaatgtc actgatgtgctgacgcccgcccagctgaatgtgttgtccaagtcaagcggctgcgcctac caggacgtgggggtgacttgcccggagcaggacaaataccgcaccatcaccgggatgtgc aacaacagacgcagccccacgctgggggcctccaaccgtgcctttgtgcgctggctgccg gcggagtatgaggacggcttctctcttccctacggctggacgcccggggtcaagcgcaac ggcttcccggtggctctggctcgcgcggtctccaacgagatcgtgcgcttccccactgat cagctgactccggaccaggagcgctcactcatgttcatgcaatggggccagctgttggac cacgacctcgacttcacccctgagccggccgcccgggcctccttcgtcactggcgtcaac tgcgagaccagctgcgttcagcagccgccctgcttcccgctcaagatcccgcccaatgac ccccgcatcaagaaccaagccgactgcatcccgttcttccgctcctgcccggcttgcccc gggagcaacatcaccatccgcaaccagatcaacgcgctcacttccttcgtggacgccagc atggtgtacggcagcgaggagcccctggccaggaacctgcgcaacatgtccaaccagctg gggctgctggccgtcaaccagcgcttccaagacaacggccgggccctgctgccctttgac aacctgcacgatgacccctgtctcctcaccaaccgctcagcgcgcatcccctgcttcctg gcaggggacacccgttccagtgagatgcccgagctcacctccatgcacaccctcttactt cgggagcacaaccggctggccacagagctcaagagcctgaaccctaggtgggatggggag aggctctaccaggaagcccggaagatcgtgggggccatggtccagatcatcacttaccgg gactacctgcccctggtgctggggccaacggccatgaggaagtacctgcccacgtaccgt tcctacaatgactcagtggacccacgcatcgccaacgtcttcaccaatgccttccgctac ggccacaccctcatccaacccttcatgttccgcctggacaatcggtaccagcccatggaa cccaacccccgtgtccccctcagcagggtcttttttgcctcctggagggtcgtgctggaa ggtggcattgaccccatcctccggggcctcatggccacccctgccaagctgaatcgtcag aaccaaattgcagtggatgagatccgggagcgattgtttgagcaggtcatgaggattggg ctggacctgcctgctctgaacatgcagcgcagcagggaccacggcctcccaggatacaat gcctggaggcgcttctgtgggctcccgcagcctgaaactgtgggccagctgggcacggtg ctgaggaacctgaaattggcgaggaaactgatggagcagtatggcacgcccaacaacatc gacatctggatgggcggcgtgtccgagcctctgaagcgcaaaggccgcgtgggcccactc ctcgcctgcatcatcggtacccagttcaggaagctccgggatggtgatcggttttggtgg gagaacgagggtgtgttcagcatgcagcagcgacaggccctggcccagatctcattgccc cggatcatctgcgacaacacaggcatcaccaccgtgtctaagaacaacatcttcatgtcc aactcatatccccgggactttgtcaactgcagtacacttcctgcattgaacctggcttcc tggagggaagcctcctag |
Protein Sequence | >4353 : length: 745 MGVPFFSSLRCMVDLGPCWAGGLTAEMKLLLALAGLLAILATPQPSEGAAPAVLGEVDTS LVLSSMEEAKQLVDKAYKERRESIKQRLRSGSASPMELLSYFKQPVAATRTAVRAADYLH VALDLLERKLRSLWRRPFNVTDVLTPAQLNVLSKSSGCAYQDVGVTCPEQDKYRTITGMC NNRRSPTLGASNRAFVRWLPAEYEDGFSLPYGWTPGVKRNGFPVALARAVSNEIVRFPTD QLTPDQERSLMFMQWGQLLDHDLDFTPEPAARASFVTGVNCETSCVQQPPCFPLKIPPND PRIKNQADCIPFFRSCPACPGSNITIRNQINALTSFVDASMVYGSEEPLARNLRNMSNQL GLLAVNQRFQDNGRALLPFDNLHDDPCLLTNRSARIPCFLAGDTRSSEMPELTSMHTLLL REHNRLATELKSLNPRWDGERLYQEARKIVGAMVQIITYRDYLPLVLGPTAMRKYLPTYR SYNDSVDPRIANVFTNAFRYGHTLIQPFMFRLDNRYQPMEPNPRVPLSRVFFASWRVVLE GGIDPILRGLMATPAKLNRQNQIAVDEIRERLFEQVMRIGLDLPALNMQRSRDHGLPGYN AWRRFCGLPQPETVGQLGTVLRNLKLARKLMEQYGTPNNIDIWMGGVSEPLKRKGRVGPL LACIIGTQFRKLRDGDRFWWENEGVFSMQQRQALAQISLPRIICDNTGITTVSKNNIFMS NSYPRDFVNCSTLPALNLASWREAS |