| General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information | |
|---|---|
Gene ID | 3728 |
Name | JUP |
Synonym | ARVD12|CTNNG|DP3|DPIII|PDGB|PKGB;junction plakoglobin;JUP;junction plakoglobin |
Definition | catenin (cadherin-associated protein), gamma (80kD)|catenin (cadherin-associated protein), gamma 80kDa|catenin gamma|desmoplakin III|desmoplakin-3|gamma-catenin |
Position | 17q21 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Cell junction organization;Reactome;REACT:20676 |
Pathway | Arrhythmogenic right ventricular cardiomyopathy (ARVC);KEGG PATHWAY;hsa05412 |
Pathway | Adherens junctions interactions;PID Reactome;500120 |
Pathway | Alzheimer disease-presenilin pathway;PANTHER;P00004 |
Pathway | E-cadherin signaling in the nascent adherens junction;PID Curated;200105 |
Pathway | Pathways in cancer;KEGG PATHWAY;hsa05200 |
Pathway | Acute myeloid leukemia;KEGG PATHWAY;hsa05221 |
Disease | Arrhythmogenic right ventricular cardiomyopathy (ARVC);KEGG DISEASE;H00293 |
Disease | Circulatory system diseases;KEGG DISEASE |
Disease | Arrhythmogenic right ventricular dysplasia, familial, 12;OMIM |
Disease | Cardiac diseases;KEGG DISEASE |
Disease | Cancer;FunDO |
Disease | Skin disease, Genetic;FunDO |
Disease | Naxos disease;OMIM |
External Links | |
Links to Entrez Gene | 3728 |
Links to all GeneRIF Items | 3728 |
Links to iHOP | 3728 |
Sequence Information | |
Nucleotide Sequence | >3728 : length: 2238 atggaggtgatgaacctgatggagcagcctatcaaggtgactgagtggcagcagacatac acctacgactcgggtatccactcgggcgccaacacctgcgtgccctccgtcagcagcaag ggcatcatggaggaggatgaggcctgcgggcgccagtacacgctcaagaaaaccaccact tacacccagggggtgccccccagccaaggtgatctggagtaccagatgtccacaacagcc agggccaaacgggtgcgggaggccatgtgccctggtgtgtcaggcgaggacagctcgctt ctgctggccacccaggtggaggggcaggccaccaacctgcagcgactggccgagccgtcc cagctgctcaagtcggccattgtgcatctcatcaactaccaggacgatgccgagctggcc actcgcgccctgcccgagctcaccaaactgctcaacgacgaggacccggtggtggtgacc aaggcggccatgattgtgaaccagctgtcgaagaaggaggcgtcgcggcgggccctgatg ggctcgccccagctggtggccgctgtcgtgcgtaccatgcagaataccagcgacctggac acagcccgctgcaccaccagcatcctgcacaacctctcccaccaccgggaggggctgctc gccatcttcaagtcgggtggcatccctgctctggtccgcatgctcagctcccctgtggag tcggtcctgttctatgccatcaccacgctgcacaacctgctcctgtaccaggagggcgcc aagatggccgtgcgcctggccgacgggctgcaaaagatggtgcccctgctcaacaagaac aaccccaagttcctggccatcaccaccgactgcctgcagctcctggcctacggcaaccag gagagcaagctgatcatcctggccaatggtgggccccaggccctcgtgcagatcatgcgt aactacagttatgaaaagctgctctggaccaccagtcgtgtgctcaaggtgctatccgtg tgtcccagcaataagcctgccattgtggaggctggtgggatgcaggccctgggcaagcac ctgaccagcaacagcccccgcctggtgcagaactgcctgtggaccctgcgcaacctctca gatgtggccaccaagcaggagggcctggagagtgtgctgaagattctggtgaatcagctg agtgtggatgacgtcaacgtcctcacctgtgccacgggcacactctccaacctgacatgc aacaacagcaagaacaagacgctggtgacacagaacagcggtgtggaggctctcatccat gccatcctgcgtgctggtgacaaggacgacatcacggagcctgccgtctgcgctctgcgc cacctcactagccgccaccctgaggccgagatggcccagaactctgtgcgtctcaactat ggcatcccagccatcgtgaagctgctcaaccagcccaaccagtggccactggtcaaggca accatcggcttgatcaggaatctggccctgtgcccagccaaccatgccccgctgcaggag gcagcggtcatcccccgcctcgtccaactgctggtgaaggcccaccaggatgcccagcgc cacgtagctgcaggcacacagcagccctacacggatggtgtgaggatggaggagattgtg gagggctgcaccggagcactgcacatcctcgcccgggaccccatgaaccgcatggagatc ttccggctcaacaccattcccctgtttgtgcagctcctgtactcgtcggtggagaacatc cagcgcgtggctgccggggtgctgtgtgagctggcccaggacaaggaggcggccgacgcc attgatgcagagggggcctcggccccactcatggagttgctgcactcccgcaacgagggc actgccacctacgctgctgccgtcctgttccgcatctccgaggacaagaacccagactac cggaagcgcgtgtccgtggagctcaccaactccctcttcaagcatgacccggctgcctgg gaggctgcccagagcatgattcccatcaatgagccctatggagatgacatggatgccacc taccgccccatgtactccagcgatgtgccccttgacccgctggagatgcacatggacatg gatggagactaccccatcgacacctacagcgacggcctcaggcccccgtaccccactgca gaccacatgctggcctag |
Protein Sequence | >3728 : length: 745 MEVMNLMEQPIKVTEWQQTYTYDSGIHSGANTCVPSVSSKGIMEEDEACGRQYTLKKTTT YTQGVPPSQGDLEYQMSTTARAKRVREAMCPGVSGEDSSLLLATQVEGQATNLQRLAEPS QLLKSAIVHLINYQDDAELATRALPELTKLLNDEDPVVVTKAAMIVNQLSKKEASRRALM GSPQLVAAVVRTMQNTSDLDTARCTTSILHNLSHHREGLLAIFKSGGIPALVRMLSSPVE SVLFYAITTLHNLLLYQEGAKMAVRLADGLQKMVPLLNKNNPKFLAITTDCLQLLAYGNQ ESKLIILANGGPQALVQIMRNYSYEKLLWTTSRVLKVLSVCPSNKPAIVEAGGMQALGKH LTSNSPRLVQNCLWTLRNLSDVATKQEGLESVLKILVNQLSVDDVNVLTCATGTLSNLTC NNSKNKTLVTQNSGVEALIHAILRAGDKDDITEPAVCALRHLTSRHPEAEMAQNSVRLNY GIPAIVKLLNQPNQWPLVKATIGLIRNLALCPANHAPLQEAAVIPRLVQLLVKAHQDAQR HVAAGTQQPYTDGVRMEEIVEGCTGALHILARDPMNRMEIFRLNTIPLFVQLLYSSVENI QRVAAGVLCELAQDKEAADAIDAEGASAPLMELLHSRNEGTATYAAAVLFRISEDKNPDY RKRVSVELTNSLFKHDPAAWEAAQSMIPINEPYGDDMDATYRPMYSSDVPLDPLEMHMDM DGDYPIDTYSDGLRPPYPTADHMLA |