| General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information | |
|---|---|
Gene ID | 23405 |
Name | DICER1 |
Synonym | DCR1|Dicer|HERNA|MNG1;dicer 1, ribonuclease type III;DICER1;dicer 1, ribonuclease type III |
Definition | Dicer1, Dcr-1 homolog|K12H4.8-LIKE|dicer 1, double-stranded RNA-specific endoribonuclease|endoribonuclease Dicer|helicase MOI|helicase with RNAse motif|helicase-moi |
Position | 14q32.13 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | dicer pathway;PID BioCarta;100188 |
Pathway | MicroRNA (miRNA) Biogenesis;PID Reactome;500366 |
Pathway | Regulatory RNA pathways;Reactome;REACT:12472 |
Disease | Pleuropulmonary blastoma;OMIM |
External Links | |
Links to Entrez Gene | 23405 |
Links to all GeneRIF Items | 23405 |
Links to iHOP | 23405 |
Sequence Information | |
Nucleotide Sequence | >23405 : length: 5490 atgaaaagccctgctttgcaacccctcagcatggcaggcctgcagctcatgacccctgct tcctcaccaatgggtcctttctttggactgccatggcaacaagaagcaattcatgataac atttatacgccaagaaaatatcaggttgaactgcttgaagcagctctggatcataatacc atcgtctgtttaaacactggctcagggaagacatttattgcagtactactcactaaagag ctgtcctatcagatcaggggagacttcagcagaaatggaaaaaggacggtgttcttggtc aactctgcaaaccaggttgctcaacaagtgtcagctgtcagaactcattcagatctcaag gttggggaatactcaaacctagaagtaaatgcatcttggacaaaagagagatggaaccaa gagtttactaagcaccaggttctcattatgacttgctatgtcgccttgaatgttttgaaa aatggttacttatcactgtcagacattaaccttttggtgtttgatgagtgtcatcttgca atcctagaccacccctatcgagaaattatgaagctctgtgaaaattgtccatcatgtcct cgcattttgggactaactgcttccattttaaatgggaaatgtgatccagaggaattggaa gaaaagattcagaaactagagaaaattcttaagagtaatgctgaaactgcaactgacctg gtggtcttagacaggtatacttctcagccatgtgagattgtggtggattgtggaccattt actgacagaagtgggctttatgaaagactgctgatggaattagaagaagcacttaatttt atcaatgattgtaatatatctgtacattcaaaagaaagagattctactttaatttcgaaa cagatactatcagactgtcgtgccgtattggtagttctgggaccctggtgtgcagataaa gtagctggaatgatggtaagagaactacagaaatacatcaaacatgagcaagaggagctg cacaggaaatttttattgtttacagacactttcctaaggaaaatacatgcactatgtgaa gagcacttctcacctgcctcacttgacctgaaatttgtaactcctaaagtaatcaaactg ctcgaaatcttacgcaaatataaaccatatgagcgacagcagtttgaaagcgttgagtgg tataataatagaaatcaggataattatgtgtcatggagtgattctgaggatgatgatgag gatgaagaaattgaagaaaaagagaagccagagacaaattttccttctccttttaccaac attttgtgcggaattatttttgtggaaagaagatacacagcagttgtcttaaacagattg ataaaggaagctggcaaacaagatccagagctggcttatatcagtagcaatttcataact ggacatggcattgggaagaatcagcctcgcaacaaacagatggaagcagaattcagaaaa caggaagaggtacttaggaaatttcgagcacatgagaccaacctgcttattgcaacaagt attgtagaagagggtgttgatataccaaaatgcaacttggtggttcgttttgatttgccc acagaatatcgatcctatgttcaatctaaaggaagagcaagggcacccatctctaattat ataatgttagcggatacagacaaaataaaaagttttgaagaagaccttaaaacctacaaa gctattgaaaagatcttgagaaacaagtgttccaagtcggttgatactggtgagactgac attgatcctgtcatggatgatgatgacgttttcccaccatatgtgttgaggcctgacgat ggtggtccacgagtcacaatcaacacggccattggacacatcaatagatactgtgctaga ttaccaagtgatccgtttactcatctagctcctaaatgcagaacccgagagttgcctgat ggtacattttattcaactctttatctgccaattaactcacctcttcgagcctccattgtt ggtccaccaatgagctgtgtacgattggctgaaagagttgtagctctcatttgctgtgag aaactgcacaaaattggcgaactggatgaccatttgatgccagttgggaaagagactgtt aaatatgaagaggagcttgatttgcatgatgaagaagagaccagtgttccaggaagacca ggttccacgaaacgaaggcagtgctacccaaaagcaattccagagtgtttgagggatagt tatcccagacctgatcagccctgttacctgtatgtgataggaatggttttaactacacct ttacctgatgaactcaactttagaaggcggaagctctatcctcctgaagataccacaaga tgctttggaatactgacggccaaacccatacctcagattccacactttcctgtgtacaca cgctctggagaggttaccatatccattgagttgaagaagtctggtttcatgttgtctcta caaatgcttgagttgattacaagacttcaccagtatatattctcacatattcttcggctt gaaaaacctgcactagaatttaaacctacagacgctgattcagcatactgtgttctacct cttaatgttgttaatgactccagcactttggatattgactttaaattcatggaagatatt gagaagtctgaagctcgcataggcattcccagtacaaagtatacaaaagaaacacccttt gtttttaaattagaagattaccaagatgccgttatcattccaagatatcgcaattttgat cagcctcatcgattttatgtagctgatgtgtacactgatcttaccccactcagtaaattt ccttcccctgagtatgaaacttttgcagaatattataaaacaaagtacaaccttgaccta accaatctcaaccagccactgctggatgtggaccacacatcttcaagacttaatcttttg acacctcgacatttgaatcagaaggggaaagcgcttcctttaagcagtgctgagaagagg aaagccaaatgggaaagtctgcagaataaacagatactggttccagaactctgtgctata catccaattccagcatcactgtggagaaaagctgtttgtctccccagcatactttatcgc cttcactgccttttgactgcagaggagctaagagcccagactgccagcgatgctggcgtg ggagtcagatcacttcctgcggattttagataccctaacttagacttcgggtggaaaaaa tctattgacagcaaatctttcatctcaatttctaactcctcttcagctgaaaatgataat tactgtaagcacagcacaattgtccctgaaaatgctgcacatcaaggtgctaatagaacc tcctctctagaaaatcatgaccaaatgtctgtgaactgcagaacgttgctcagcgagtcc cctggtaagctccacgttgaagtttcagcagatcttacagcaattaatggtctttcttac aatcaaaatctcgccaatggcagttatgatttagctaacagagacttttgccaaggaaat cagctaaattactacaagcaggaaatacccgtgcaaccaactacctcatattccattcag aatttatacagttacgagaaccagccccagcccagcgatgaatgtactctcctgagtaat aaataccttgatggaaatgctaacaaatctacctcagatggaagtcctgtgatggccgta atgcctggtacgacagacactattcaagtgctcaagggcaggatggattctgagcagagc ccttctattgggtactcctcaaggactcttggccccaatcctggacttattcttcaggct ttgactctgtcaaacgctagtgatggatttaacctggagcggcttgaaatgcttggcgac tcctttttaaagcatgccatcaccacatatctattttgcacttaccctgatgcgcatgag ggccgcctttcatatatgagaagcaaaaaggtcagcaactgtaatctgtatcgccttgga aaaaagaagggactacccagccgcatggtggtgtcaatatttgatccccctgtgaattgg cttcctcctggttatgtagtaaatcaagacaaaagcaacacagataaatgggaaaaagat gaaatgacaaaagactgcatgctggcgaatggcaaactggatgaggattacgaggaggag gatgaggaggaggagagcctgatgtggagggctccgaaggaagaggctgactatgaagat gatttcctggagtatgatcaggaacatatcagatttatagataatatgttaatggggtca ggagcttttgtaaagaaaatctctctttctcctttttcaaccactgattctgcatatgaa tggaaaatgcccaaaaaatcctccttaggtagtatgccattttcatcagattttgaggat tttgactacagctcttgggatgcaatgtgctatctggatcctagcaaagctgttgaagaa gatgactttgtggtggggttctggaatccatcagaagaaaactgtggtgttgacacggga aagcagtccatttcttacgacttgcacactgagcagtgtattgctgacaaaagcatagcg gactgtgtggaagccctgctgggctgctatttaaccagctgtggggagagggctgctcag cttttcctctgttcactggggctgaaggtgctcccggtaattaaaaggactgatcgggaa aaggccctgtgccctactcgggagaatttcaacagccaacaaaagaacctttcagtgagc tgtgctgctgcttctgtggccagttcacgctcttctgtattgaaagactcggaatatggt tgtttgaagattccaccaagatgtatgtttgatcatccagatgcagataaaacactgaat caccttatatcggggtttgaaaattttgaaaagaaaatcaactacagattcaagaataag gcttaccttctccaggcttttacacatgcctcctaccactacaatactatcactgattgt taccagcgcttagaattcctgggagatgcgattttggactacctcataaccaagcacctt tatgaagacccgcggcagcactccccgggggtcctgacagacctgcggtctgccctggtc aacaacaccatctttgcatcgctggctgtaaagtacgactaccacaagtacttcaaagct gtctctcctgagctcttccatgtcattgatgactttgtgcagtttcagcttgagaagaat gaaatgcaaggaatggattctgagaaaagttttctgcaaatgtaccccgttcccctgtgc gagaattgcttgaaatggaaccagaaactgccaaatttagcccggctgagagaacttacg acgggaaggtcagagtcactgtggaagtag |
Protein Sequence | >23405 : length: 1829 MKSPALQPLSMAGLQLMTPASSPMGPFFGLPWQQEAIHDNIYTPRKYQVELLEAALDHNT IVCLNTGSGKTFIAVLLTKELSYQIRGDFSRNGKRTVFLVNSANQVAQQVSAVRTHSDLK VGEYSNLEVNASWTKERWNQEFTKHQVLIMTCYVALNVLKNGYLSLSDINLLVFDECHLA ILDHPYREIMKLCENCPSCPRILGLTASILNGKCDPEELEEKIQKLEKILKSNAETATDL VVLDRYTSQPCEIVVDCGPFTDRSGLYERLLMELEEALNFINDCNISVHSKERDSTLISK QILSDCRAVLVVLGPWCADKVAGMMVRELQKYIKHEQEELHRKFLLFTDTFLRKIHALCE EHFSPASLDLKFVTPKVIKLLEILRKYKPYERQQFESVEWYNNRNQDNYVSWSDSEDDDE DEEIEEKEKPETNFPSPFTNILCGIIFVERRYTAVVLNRLIKEAGKQDPELAYISSNFIT GHGIGKNQPRNKQMEAEFRKQEEVLRKFRAHETNLLIATSIVEEGVDIPKCNLVVRFDLP TEYRSYVQSKGRARAPISNYIMLADTDKIKSFEEDLKTYKAIEKILRNKCSKSVDTGETD IDPVMDDDDVFPPYVLRPDDGGPRVTINTAIGHINRYCARLPSDPFTHLAPKCRTRELPD GTFYSTLYLPINSPLRASIVGPPMSCVRLAERVVALICCEKLHKIGELDDHLMPVGKETV KYEEELDLHDEEETSVPGRPGSTKRRQCYPKAIPECLRDSYPRPDQPCYLYVIGMVLTTP LPDELNFRRRKLYPPEDTTRCFGILTAKPIPQIPHFPVYTRSGEVTISIELKKSGFMLSL QMLELITRLHQYIFSHILRLEKPALEFKPTDADSAYCVLPLNVVNDSSTLDIDFKFMEDI EKSEARIGIPSTKYTKETPFVFKLEDYQDAVIIPRYRNFDQPHRFYVADVYTDLTPLSKF PSPEYETFAEYYKTKYNLDLTNLNQPLLDVDHTSSRLNLLTPRHLNQKGKALPLSSAEKR KAKWESLQNKQILVPELCAIHPIPASLWRKAVCLPSILYRLHCLLTAEELRAQTASDAGV GVRSLPADFRYPNLDFGWKKSIDSKSFISISNSSSAENDNYCKHSTIVPENAAHQGANRT SSLENHDQMSVNCRTLLSESPGKLHVEVSADLTAINGLSYNQNLANGSYDLANRDFCQGN QLNYYKQEIPVQPTTSYSIQNLYSYENQPQPSDECTLLSNKYLDGNANKSTSDGSPVMAV MPGTTDTIQVLKGRMDSEQSPSIGYSSRTLGPNPGLILQALTLSNASDGFNLERLEMLGD SFLKHAITTYLFCTYPDAHEGRLSYMRSKKVSNCNLYRLGKKKGLPSRMVVSIFDPPVNW LPPGYVVNQDKSNTDKWEKDEMTKDCMLANGKLDEDYEEEDEEEESLMWRAPKEEADYED DFLEYDQEHIRFIDNMLMGSGAFVKKISLSPFSTTDSAYEWKMPKKSSLGSMPFSSDFED FDYSSWDAMCYLDPSKAVEEDDFVVGFWNPSEENCGVDTGKQSISYDLHTEQCIADKSIA DCVEALLGCYLTSCGERAAQLFLCSLGLKVLPVIKRTDREKALCPTRENFNSQQKNLSVS CAAASVASSRSSVLKDSEYGCLKIPPRCMFDHPDADKTLNHLISGFENFEKKINYRFKNK AYLLQAFTHASYHYNTITDCYQRLEFLGDAILDYLITKHLYEDPRQHSPGVLTDLRSALV NNTIFASLAVKYDYHKYFKAVSPELFHVIDDFVQFQLEKNEMQGMDSEKSFLQMYPVPLC ENCLKWNQKLPNLARLRELTTGRSESLWK |