| General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information | |
|---|---|
Gene ID | 2052 |
Name | EPHX1 |
Synonym | EPHX|EPOX|HYL1|MEH;epoxide hydrolase 1, microsomal (xenobiotic);EPHX1;epoxide hydrolase 1, microsomal (xenobiotic) |
Definition | epoxide hydratase|epoxide hydrolase 1 |
Position | 1q42.1 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Metabolism of xenobiotics by cytochrome P450;KEGG PATHWAY;hsa00980 |
Pathway | eicosanoid metabolism;PID BioCarta;100180 |
Disease | Preeclampsia, susceptibility to;OMIM |
Disease | emphysema;GAD |
Disease | asbestosis or pleural plaques;GAD |
Disease | Lung cancer;FunDO |
Disease | polycystic ovary syndrome.;GAD |
Disease | Diphenylhydantoin toxicity;OMIM |
Disease | COPD severity;GAD |
Disease | Fetal hydantoin syndrome;OMIM |
Disease | Liver cancer;FunDO |
Disease | Breast cancer;FunDO |
Disease | Parkinson disease;FunDO |
Disease | Embryoma;FunDO |
Disease | Emphysema;FunDO |
Disease | lung cancer;GAD |
Disease | IMMUNE;GAD |
Disease | preeclampsia.;GAD |
Disease | DNA Damage;GAD |
Disease | prostate cancer;GAD |
Disease | head and neck cancer;GAD |
Disease | Liver disease;FunDO |
Disease | METABOLIC;GAD |
Disease | Yersinia infection;FunDO |
Disease | Colon cancer;FunDO |
Disease | Larynx cancer;FunDO |
Disease | colorectal cancer;GAD |
Disease | Pre-Eclampsia;FunDO |
Disease | infant birthweight;GAD |
Disease | esophageal cancer;GAD |
Disease | Adenoma;FunDO |
Disease | preeclampsia;GAD |
Disease | CARDIOVASCULAR;GAD |
Disease | CANCER;GAD |
Disease | colorectal polyps (adenoma or hyperplastic);GAD |
Disease | Birth Weight;GAD |
Disease | Chronic obstructive airway disease;FunDO |
Disease | REPRODUCTION;GAD |
Disease | Squamous cell cancer;FunDO |
Disease | Hypercholanemia, familial;OMIM |
Disease | Optic atrophy;FunDO |
Disease | COPD;GAD |
Disease | Ovarian cancer;FunDO |
Disease | chronic obstructive pulmonary disease/COPD;GAD |
Disease | polycystic ovary syndrome;GAD |
Disease | PAH-DNA adducts;GAD |
Disease | Atherosclerosis;FunDO |
External Links | |
Links to Entrez Gene | 2052 |
Links to all GeneRIF Items | 2052 |
Links to iHOP | 2052 |
Sequence Information | |
Nucleotide Sequence | >2052 : length: 1368 atgtggctagaaatcctcctcacttcagtgctgggctttgccatctactggttcatctcc cgggacaaagaggaaactttgccacttgaagatgggtggtgggggccaggcacgaggtcc gcagccagggaggacgacagcatccgccctttcaaggtggaaacgtcagatgaggagatc cacgacttacaccagaggatcgataagttccgtttcaccccacctttggaggacagctgc ttccactatggcttcaactccaactacctgaagaaagtcatctcctactggcggaatgaa tttgactggaagaagcaggtggagattctcaacagataccctcacttcaagactaagatt gaagggctggacatccacttcatccacgtgaagcccccccagctgcccgcaggccatacc ccgaagcccttgctgatggtgcacggctggcccggctctttctacgagttttataagatc atcccactcctgactgaccccaagaaccatggcctgagcgatgagcacgtttttgaagtc atctgcccttccatccctggctatggcttctcagaggcatcctccaagaaggggttcaac tcggtggccaccgccaggatcttttacaagctgatgctgcggctgggcttccaggaattc tacattcaaggaggggactgggggtccctgatctgcactaatatggcccagctggtgccc agccacgtgaaaggcctgcacttgaacatggctttggttttaagcaacttctctaccctg accctcctcctgggacagcgtttcgggaggtttcttggcctcactgagagggatgtggag ctgctgtaccccgtcaaggagaaggtattctacagcctgatgagggagagcggctacatg cacatccagtgcaccaagcctgacaccgtaggctctgctctgaatgactctcctgtgggt ctggctgcctatattctagagaagttttccacctggaccaatacggaattccgatacctg gaggatggaggcctggaaaggaagttctccctggacgacctgctgaccaacgtcatgctc tactggacaacaggcaccatcatctcctcccagcgcttctacaaggagaacctgggacag ggctggatgacccagaagcatgagcggatgaaggtctatgtgcccactggcttctctgcc ttcccttttgagctattgcacacgcctgaaaagtgggtgaggttcaagtacccaaagctc atctcctattcctacatggttcgtgggggccactttgcggcctttgaggagccggagctg ctcgcccaggacatccgcaagttcctgtcggtgctggagcggcaatga |
Protein Sequence | >2052 : length: 455 MWLEILLTSVLGFAIYWFISRDKEETLPLEDGWWGPGTRSAAREDDSIRPFKVETSDEEI HDLHQRIDKFRFTPPLEDSCFHYGFNSNYLKKVISYWRNEFDWKKQVEILNRYPHFKTKI EGLDIHFIHVKPPQLPAGHTPKPLLMVHGWPGSFYEFYKIIPLLTDPKNHGLSDEHVFEV ICPSIPGYGFSEASSKKGFNSVATARIFYKLMLRLGFQEFYIQGGDWGSLICTNMAQLVP SHVKGLHLNMALVLSNFSTLTLLLGQRFGRFLGLTERDVELLYPVKEKVFYSLMRESGYM HIQCTKPDTVGSALNDSPVGLAAYILEKFSTWTNTEFRYLEDGGLERKFSLDDLLTNVML YWTTGTIISSQRFYKENLGQGWMTQKHERMKVYVPTGFSAFPFELLHTPEKWVRFKYPKL ISYSYMVRGGHFAAFEEPELLAQDIRKFLSVLERQ |