| General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information | |
|---|---|
Gene ID | 1910 |
Name | EDNRB |
Synonym | ABCDS|ET-B|ET-BR|ETB|ETBR|ETRB|HSCR|HSCR2|WS4A;endothelin receptor type B;EDNRB;endothelin receptor type B |
Definition | endothelin B receptor|endothelin receptor non-selective type |
Position | 13q22 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Melanogenesis;KEGG PATHWAY;hsa04916 |
Pathway | Endothelins;PID Curated;200004 |
Pathway | Neuroactive ligand-receptor interaction;KEGG PATHWAY;hsa04080 |
Pathway | Arf6 trafficking events;PID Curated;200046 |
Pathway | Endothelin signaling pathway;PANTHER;P00019 |
Pathway | Calcium signaling pathway;KEGG PATHWAY;hsa04020 |
Pathway | Signaling by GPCR;Reactome;REACT:14797 |
Disease | Lung cancer;FunDO |
Disease | Hirschsprung Disease;GAD |
Disease | Kaposi sarcoma;FunDO |
Disease | Nasopharyngeal cancer;FunDO |
Disease | migraine;GAD |
Disease | Breast cancer;FunDO |
Disease | Down syndrome;FunDO |
Disease | Neoplasm metastasis;FunDO |
Disease | Polycystic kidney;FunDO |
Disease | Leukemia;FunDO |
Disease | atherosclerosis, generalized;GAD |
Disease | Hirschsprung's disease;GAD |
Disease | Bronchial disease;FunDO |
Disease | Retinal disease;FunDO |
Disease | Intraocular melanoma;FunDO |
Disease | Waardenburg syndrome, type 4A;OMIM |
Disease | CARDIOVASCULAR;GAD |
Disease | ABCD syndrome;OMIM |
Disease | Heart failure;FunDO |
Disease | Brain tumor;FunDO |
Disease | NEUROLOGICAL;GAD |
Disease | Renal Cell cancer;FunDO |
Disease | Hypertension;FunDO |
Disease | Cancers;KEGG DISEASE |
Disease | Squamous cell cancer;FunDO |
Disease | Nasopharyngeal cancer;KEGG DISEASE;H00054 |
Disease | Hirschsprung disease, susceptibility to, 2;OMIM |
Disease | Head and neck cancers;KEGG DISEASE |
Disease | Atherosclerosis;FunDO |
External Links | |
Links to Entrez Gene | 1910 |
Links to all GeneRIF Items | 1910 |
Links to iHOP | 1910 |
Sequence Information | |
Nucleotide Sequence | >1910 : length: 1329 atgcagccgcctccaagtctgtgcggacgcgccctggttgcgctggttcttgcctgcggc ctgtcgcggatctggggagaggagagaggcttcccgcctgacagggccactccgcttttg caaaccgcagagataatgacgccacccactaagaccttatggcccaagggttccaacgcc agtctggcgcggtcgttggcacctgcggaggtgcctaaaggagacaggacggcaggatct ccgccacgcaccatctcccctcccccgtgccaaggacccatcgagatcaaggagactttc aaatacatcaacacggttgtgtcctgccttgtgttcgtgctggggatcatcgggaactcc acacttctgagaattatctacaagaacaagtgcatgcgaaacggtcccaatatcttgatc gccagcttggctctgggagacctgctgcacatcgtcattgacatccctatcaatgtctac aagctgctggcagaggactggccatttggagctgagatgtgtaagctggtgcctttcata cagaaagcctccgtgggaatcactgtgctgagtctatgtgctctgagtattgacagatat cgagctgttgcttcttggagtagaattaaaggaattggggttccaaaatggacagcagta gaaattgttttgatttgggtggtctctgtggttctggctgtccctgaagccataggtttt gatataattacgatggactacaaaggaagttatctgcgaatctgcttgcttcatcccgtt cagaagacagctttcatgcagttttacaagacagcaaaagattggtggctattcagtttc tatttctgcttgccattggccatcactgcatttttttatacactaatgacctgtgaaatg ttgagaaagaaaagtggcatgcagattgctttaaatgatcacctaaagcagagacgggaa gtggccaaaaccgtcttttgcctggtccttgtctttgccctctgctggcttccccttcac ctcagcaggattctgaagctcactctttataatcagaatgatcccaatagatgtgaactt ttgagctttctgttggtattggactatattggtatcaacatggcttcactgaattcctgc attaacccaattgctctgtatttggtgagcaaaagattcaaaaactgctttaagtcatgc ttatgctgctggtgccagtcatttgaagaaaaacagtccttggaggaaaagcagtcgtgc ttaaagttcaaagctaatgatcacggatatgacaacttccgttccagtaataaatacagc tcatcttga |
Protein Sequence | >1910 : length: 442 MQPPPSLCGRALVALVLACGLSRIWGEERGFPPDRATPLLQTAEIMTPPTKTLWPKGSNA SLARSLAPAEVPKGDRTAGSPPRTISPPPCQGPIEIKETFKYINTVVSCLVFVLGIIGNS TLLRIIYKNKCMRNGPNILIASLALGDLLHIVIDIPINVYKLLAEDWPFGAEMCKLVPFI QKASVGITVLSLCALSIDRYRAVASWSRIKGIGVPKWTAVEIVLIWVVSVVLAVPEAIGF DIITMDYKGSYLRICLLHPVQKTAFMQFYKTAKDWWLFSFYFCLPLAITAFFYTLMTCEM LRKKSGMQIALNDHLKQRREVAKTVFCLVLVFALCWLPLHLSRILKLTLYNQNDPNRCEL LSFLLVLDYIGINMASLNSCINPIALYLVSKRFKNCFKSCLCCWCQSFEEKQSLEEKQSC LKFKANDHGYDNFRSSNKYSSS |