| General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information | |
|---|---|
Gene ID | 1789 |
Name | DNMT3B |
Synonym | ICF|ICF1|M.HsaIIIB;DNA (cytosine-5-)-methyltransferase 3 beta;DNMT3B;DNA (cytosine-5-)-methyltransferase 3 beta |
Definition | DNA (cytosine-5)-methyltransferase 3B|DNA MTase HsaIIIB|DNA methyltransferase HsaIIIB |
Position | 20q11.2 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Cysteine and methionine metabolism;KEGG PATHWAY;hsa00270 |
Pathway | Metabolic pathways;KEGG PATHWAY;hsa01100 |
Disease | Immune system diseases;KEGG DISEASE |
Disease | overall effect;GAD |
Disease | CANCER;GAD |
Disease | lung cancer;GAD |
Disease | Immunodeficiency-centromeric instability-facial anomalies syndrome;OMIM |
Disease | Primary immunodeficiency;KEGG DISEASE |
Disease | Other humoral immunodeficiencies;KEGG DISEASE;H00087 |
External Links | |
Links to Entrez Gene | 1789 |
Links to all GeneRIF Items | 1789 |
Links to iHOP | 1789 |
Sequence Information | |
Nucleotide Sequence | >1789 : length: 2562 atgaagggagacaccaggcatctcaatggagaggaggacgccggcgggagggaagactcg atcctcgtcaacggggcctgcagcgaccagtcctccgactcgcccccaatcctggaggct atccgcaccccggagatcagaggccgaagatcaagctcgcgactctccaagagggaggtg tccagtctgctaagctacacacaggacttgacaggcgatggcgacggggaagatggggat ggctctgacaccccagtcatgccaaagctcttccgggaaaccaggactcgttcagaaagc ccagctgtccgaactcgaaataacaacagtgtctccagccgggagaggcacaggccttcc ccacgttccacccgaggccggcagggccgcaaccatgtggacgagtcccccgtggagttc ccggctaccaggtccctgagacggcgggcaacagcatcggcaggaacgccatggccgtcc cctcccagctcttaccttaccatcgacctcacagacgacacagaggacacacatgggacg ccccagagcagcagtaccccctacgcccgcctagcccaggacagccagcaggggggcatg gagtccccgcaggtggaggcagacagtggagatggagacagttcagagtatcaggatggg aaggagtttggaataggggacctcgtgtggggaaagatcaagggcttctcctggtggccc gccatggtggtgtcttggaaggccacctccaagcgacaggctatgtctggcatgcggtgg gtccagtggtttggcgatggcaagttctccgaggtctctgcagacaaactggtggcactg gggctgttcagccagcactttaatttggccaccttcaataagctcgtctcctatcgaaaa gccatgtaccatgctctggagaaagctagggtgcgagctggcaagaccttccccagcagc cctggagactcattggaggaccagctgaagcccatgttggagtgggcccacgggggcttc aagcccactgggatcgagggcctcaaacccaacaacacgcaaccagtggttaataagtcg aaggtgcgtcgtgcaggcagtaggaaattagaatcaaggaaatacgagaacaagactcga agacgcacagctgacgactcagccacctctgactactgccccgcacccaagcgcctcaag acaaattgctataacaacggcaaagaccgaggggatgaagatcagagccgagaacaaatg gcttcagatgttgccaacaacaagagcagcctggaagatggctgtttgtcttgtggcagg aaaaaccccgtgtccttccaccctctctttgagggggggctctgtcagacatgccgggat cgcttccttgagctgttttacatgtatgatgacgatggctatcagtcttactgcactgtg tgctgcgagggccgagagctgctgctttgcagcaacacgagctgctgccggtgtttctgt gtggagtgcctggaggtgctggtgggcacaggcacagcggccgaggccaagcttcaggag ccctggagctgttacatgtgtctcccgcagcgctgtcatggcgtcctgcggcgccggaag gactggaacgtgcgcctgcaggccttcttcaccagtgacacggggcttgaatatgaagcc cccaagctgtaccctgccattcccgcagcccgaaggcggcccattcgagtcctgtcattg tttgatggcatcgcgacaggctacctagtcctcaaagagttgggcataaaggtaggaaag tacgtcgcttctgaagtgtgtgaggagtccattgctgttggaaccgtgaagcacgagggg aatatcaaatacgtgaacgacgtgaggaacatcacaaagaaaaatattgaagaatggggc ccatttgacttggtgattggcggaagcccatgcaacgatctctcaaatgtgaatccagcc aggaaaggcctgtatgagggtacaggccggctcttcttcgaattttaccacctgctgaat tactcacgccccaaggagggtgatgaccggccgttcttctggatgtttgagaatgttgta gccatgaaggttggcgacaagagggacatctcacggttcctggagtgtaatccagtgatg attgatgccatcaaagtttctgctgctcacagggcccgatacttctggggcaacctaccc gggatgaacaggcccgtgatagcatcaaagaatgataaactcgagctgcaggactgcttg gaatacaataggatagccaagttaaagaaagtacagacaataaccaccaagtcgaactcg atcaaacaggggaaaaaccaacttttccctgttgtcatgaatggcaaagaagatgttttg tggtgcactgagctcgaaaggatctttggctttcctgtgcactacacagacgtgtccaac atgggccgtggtgcccgccagaagctgctgggaaggtcctggagcgtgcctgtcatccga cacctcttcgcccctctgaaggactactttgcatgtgaatag |
Protein Sequence | >1789 : length: 853 MKGDTRHLNGEEDAGGREDSILVNGACSDQSSDSPPILEAIRTPEIRGRRSSSRLSKREV SSLLSYTQDLTGDGDGEDGDGSDTPVMPKLFRETRTRSESPAVRTRNNNSVSSRERHRPS PRSTRGRQGRNHVDESPVEFPATRSLRRRATASAGTPWPSPPSSYLTIDLTDDTEDTHGT PQSSSTPYARLAQDSQQGGMESPQVEADSGDGDSSEYQDGKEFGIGDLVWGKIKGFSWWP AMVVSWKATSKRQAMSGMRWVQWFGDGKFSEVSADKLVALGLFSQHFNLATFNKLVSYRK AMYHALEKARVRAGKTFPSSPGDSLEDQLKPMLEWAHGGFKPTGIEGLKPNNTQPVVNKS KVRRAGSRKLESRKYENKTRRRTADDSATSDYCPAPKRLKTNCYNNGKDRGDEDQSREQM ASDVANNKSSLEDGCLSCGRKNPVSFHPLFEGGLCQTCRDRFLELFYMYDDDGYQSYCTV CCEGRELLLCSNTSCCRCFCVECLEVLVGTGTAAEAKLQEPWSCYMCLPQRCHGVLRRRK DWNVRLQAFFTSDTGLEYEAPKLYPAIPAARRRPIRVLSLFDGIATGYLVLKELGIKVGK YVASEVCEESIAVGTVKHEGNIKYVNDVRNITKKNIEEWGPFDLVIGGSPCNDLSNVNPA RKGLYEGTGRLFFEFYHLLNYSRPKEGDDRPFFWMFENVVAMKVGDKRDISRFLECNPVM IDAIKVSAAHRARYFWGNLPGMNRPVIASKNDKLELQDCLEYNRIAKLKKVQTITTKSNS IKQGKNQLFPVVMNGKEDVLWCTELERIFGFPVHYTDVSNMGRGARQKLLGRSWSVPVIR HLFAPLKDYFACE |