| General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information | |
|---|---|
Gene ID | 1788 |
Name | DNMT3A |
Synonym | DNMT3A2|M.HsaIIIA;DNA (cytosine-5-)-methyltransferase 3 alpha;DNMT3A;DNA (cytosine-5-)-methyltransferase 3 alpha |
Definition | DNA (cytosine-5)-methyltransferase 3A|DNA MTase HsaIIIA|DNA cytosine methyltransferase 3A2 |
Position | 2p23 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Cysteine and methionine metabolism;KEGG PATHWAY;hsa00270 |
Pathway | Validated targets of C-MYC transcriptional repression;PID Curated;200171 |
Pathway | Metabolic pathways;KEGG PATHWAY;hsa01100 |
Disease | CANCER;GAD |
Disease | DEVELOPMENTAL;GAD |
Disease | height;GAD |
Disease | ER negative;GAD |
External Links | |
Links to Entrez Gene | 1788 |
Links to all GeneRIF Items | 1788 |
Links to iHOP | 1788 |
Sequence Information | |
Nucleotide Sequence | >1788 : length: 2739 atgcccgccatgccctccagcggccccggggacaccagcagctctgctgcggagcgggag gaggaccgaaaggacggagaggagcaggaggagccgcgtggcaaggaggagcgccaagag cccagcaccacggcacggaaggtggggcggcctgggaggaagcgcaagcaccccccggtg gaaagcggtgacacgccaaaggaccctgcggtgatctccaagtccccatccatggcccag gactcaggcgcctcagagctattacccaatggggacttggagaagcggagtgagccccag ccagaggaggggagccctgctggggggcagaagggcggggccccagcagagggagagggt gcagctgagaccctgcctgaagcctcaagagcagtggaaaatggctgctgcacccccaag gagggccgaggagcccctgcagaagcgggcaaagaacagaaggagaccaacatcgaatcc atgaaaatggagggctcccggggccggctgcggggtggcttgggctgggagtccagcctc cgtcagcggcccatgccgaggctcaccttccaggcgggggacccctactacatcagcaag cgcaagcgggacgagtggctggcacgctggaaaagggaggctgagaagaaagccaaggtc attgcaggaatgaatgctgtggaagaaaaccaggggcccggggagtctcagaaggtggag gaggccagccctcctgctgtgcagcagcccactgaccccgcatcccccactgtggctacc acgcctgagcccgtggggtccgatgctggggacaagaatgccaccaaagcaggcgatgac gagccagagtacgaggacggccggggctttggcattggggagctggtgtgggggaaactg cggggcttctcctggtggccaggccgcattgtgtcttggtggatgacgggccggagccga gcagctgaaggcacccgctgggtcatgtggttcggagacggcaaattctcagtggtgtgt gttgagaagctgatgccgctgagctcgttttgcagtgcgttccaccaggccacgtacaac aagcagcccatgtaccgcaaagccatctacgaggtcctgcaggtggccagcagccgcgcg gggaagctgttcccggtgtgccacgacagcgatgagagtgacactgccaaggccgtggag gtgcagaacaagcccatgattgaatgggccctggggggcttccagccttctggccctaag ggcctggagccaccagaagaagagaagaatccctacaaagaagtgtacacggacatgtgg gtggaacctgaggcagctgcctacgcaccacctccaccagccaaaaagccccggaagagc acagcggagaagcccaaggtcaaggagattattgatgagcgcacaagagagcggctggtg tacgaggtgcggcagaagtgccggaacattgaggacatctgcatctcctgtgggagcctc aatgttaccctggaacaccccctcttcgttggaggaatgtgccaaaactgcaagaactgc tttctggagtgtgcgtaccagtacgacgacgacggctaccagtcctactgcaccatctgc tgtgggggccgtgaggtgctcatgtgcggaaacaacaactgctgcaggtgcttttgcgtg gagtgtgtggacctcttggtggggccgggggctgcccaggcagccattaaggaagacccc tggaactgctacatgtgcgggcacaagggtacctacgggctgctgcggcggcgagaggac tggccctcccggctccagatgttcttcgctaataaccacgaccaggaatttgaccctcca aaggtttacccacctgtcccagctgagaagaggaagcccatccgggtgctgtctctcttt gatggaatcgctacagggctcctggtgctgaaggacttgggcattcaggtggaccgctac attgcctcggaggtgtgtgaggactccatcacggtgggcatggtgcggcaccaggggaag atcatgtacgtcggggacgtccgcagcgtcacacagaagcatatccaggagtggggccca ttcgatctggtgattgggggcagtccctgcaatgacctctccatcgtcaaccctgctcgc aagggcctctacgagggcactggccggctcttctttgagttctaccgcctcctgcatgat gcgcggcccaaggagggagatgatcgccccttcttctggctctttgagaatgtggtggcc atgggcgttagtgacaagagggacatctcgcgatttctcgagtccaaccctgtgatgatt gatgccaaagaagtgtcagctgcacacagggcccgctacttctggggtaaccttcccggt atgaacaggccgttggcatccactgtgaatgataagctggagctgcaggagtgtctggag catggcaggatagccaagttcagcaaagtgaggaccattactacgaggtcaaactccata aagcagggcaaagaccagcattttcctgtcttcatgaatgagaaagaggacatcttatgg tgcactgaaatggaaagggtatttggtttcccagtccactatactgacgtctccaacatg agccgcttggcgaggcagagactgctgggccggtcatggagcgtgccagtcatccgccac ctcttcgctccgctgaaggagtattttgcgtgtgtgtaa |
Protein Sequence | >1788 : length: 912 MPAMPSSGPGDTSSSAAEREEDRKDGEEQEEPRGKEERQEPSTTARKVGRPGRKRKHPPV ESGDTPKDPAVISKSPSMAQDSGASELLPNGDLEKRSEPQPEEGSPAGGQKGGAPAEGEG AAETLPEASRAVENGCCTPKEGRGAPAEAGKEQKETNIESMKMEGSRGRLRGGLGWESSL RQRPMPRLTFQAGDPYYISKRKRDEWLARWKREAEKKAKVIAGMNAVEENQGPGESQKVE EASPPAVQQPTDPASPTVATTPEPVGSDAGDKNATKAGDDEPEYEDGRGFGIGELVWGKL RGFSWWPGRIVSWWMTGRSRAAEGTRWVMWFGDGKFSVVCVEKLMPLSSFCSAFHQATYN KQPMYRKAIYEVLQVASSRAGKLFPVCHDSDESDTAKAVEVQNKPMIEWALGGFQPSGPK GLEPPEEEKNPYKEVYTDMWVEPEAAAYAPPPPAKKPRKSTAEKPKVKEIIDERTRERLV YEVRQKCRNIEDICISCGSLNVTLEHPLFVGGMCQNCKNCFLECAYQYDDDGYQSYCTIC CGGREVLMCGNNNCCRCFCVECVDLLVGPGAAQAAIKEDPWNCYMCGHKGTYGLLRRRED WPSRLQMFFANNHDQEFDPPKVYPPVPAEKRKPIRVLSLFDGIATGLLVLKDLGIQVDRY IASEVCEDSITVGMVRHQGKIMYVGDVRSVTQKHIQEWGPFDLVIGGSPCNDLSIVNPAR KGLYEGTGRLFFEFYRLLHDARPKEGDDRPFFWLFENVVAMGVSDKRDISRFLESNPVMI DAKEVSAAHRARYFWGNLPGMNRPLASTVNDKLELQECLEHGRIAKFSKVRTITTRSNSI KQGKDQHFPVFMNEKEDILWCTEMERVFGFPVHYTDVSNMSRLARQRLLGRSWSVPVIRH LFAPLKEYFACV |