Cell senescence gene database Home
Cell senescence database
General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

5553

Name

PRG2

Synonymous

proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein);PRG2;proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)

Definition

bone marrow proteoglycan|bone-marrow proteoglycan|eosinophil granule major basic protein|eosinophil major basic protein|natural killer cell activator|proteoglycan 2 preproprotein

Position

11q12

Gene Type

protein-coding

COSMIC somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.1277C>T; p.P426L; 19:813534-813534

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1777G>A; p.D593N; 19:813034-813034

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.897G>A; p.A299A; 19:814452-814452

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - coding silent

c.581_589delACGCCATCC; p.H194_I196delHAI; 19:814896-814904

 lungcarcinoma; adenocarcinomaDeletion - In frame

c.1262T>C; p.M421T; 19:813549-813549

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1002G>A; p.L334L; 19:813809-813809

 ovaryother; neoplasmSubstitution - coding silent

c.817G>A; p.A273T; 19:814532-814532

 breastcarcinomaSubstitution - Missense

c.1862T>G; p.V621G; 19:812949-812949

 livercarcinomaSubstitution - Missense

c.1862T>G; p.V621G; 19:812949-812949

 livercarcinomaSubstitution - Missense

c.149T>G; p.V50G; 19:815778-815778

 breastcarcinomaSubstitution - Missense

c.383G>T; p.R128L; 19:815206-815206

 NSmalignant_melanomaSubstitution - Missense

c.83T>C; p.I28T; 19:815844-815844

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.870C>A; p.D290E; 19:814479-814479

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.1687C>T; p.R563W; 19:813124-813124

 oesophagus; lower_thirdcarcinoma; adenocarcinomaSubstitution - Missense

c.177C>T; p.L59L; 19:815750-815750

 breastcarcinomaSubstitution - coding silent

c.1687C>T; p.R563W; 19:813124-813124

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.424T>C; p.C142R; 19:815061-815061

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.697C>G; p.L233V; 19:814652-814652

 breastcarcinomaSubstitution - Missense

c.166G>A; p.D56N; 19:815761-815761

 skinmalignant_melanomaSubstitution - Missense

c.828C>T; p.C276C; 19:814521-814521

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1704C>T; p.I568I; 19:813107-813107

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.968C>T; p.A323V; 19:813843-813843

 stomachcarcinoma; intestinal_adenocarcinomaSubstitution - Missense

c.878C>T; p.A293V; 19:814471-814471

 urinary_tract; bladdercarcinoma; transitional_cell_carcinomaSubstitution - Missense

c.878C>T; p.A293V; 19:814471-814471

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.1630C>T; p.R544C; 19:813181-813181

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.120G>C; p.E40D; 19:815807-815807

 central_nervous_system; posterior_fossaglioma; astrocytoma_Grade_IVSubstitution - Missense

c.891C>T; p.I297I; 19:814458-814458

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - coding silent

c.891C>T; p.I297I; 19:814458-814458

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - coding silent

c.1731G>A; p.P577P; 19:813080-813080

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.602A>G; p.K201R; 19:814747-814747

 kidneycarcinoma; papillary_renal_cell_carcinomaSubstitution - Missense

c.169C>T; p.R57C; 19:815758-815758

 skinmalignant_melanomaSubstitution - Missense

c.270G>A; p.V90V; 19:815319-815319

 breastcarcinomaSubstitution - coding silent

c.645G>A; p.A215A; 19:814704-814704

 boneEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - coding silent

c.881G>A; p.G294D; 19:814468-814468

 breastcarcinomaSubstitution - Missense

c.582C>A; p.H194Q; 19:814903-814903

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.556G>T; p.D186Y; 19:814929-814929

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.915+1G>A; p.?; 19:814433-814433

 oesophaguscarcinoma; adenocarcinomaUnknown

c.609C>A; p.F203L; 19:814740-814740

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.30C>T; p.I10I; 19:821530-821530

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - coding silent

c.276G>T; p.E92D; 19:815313-815313

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.30C>T; p.I10I; 19:821530-821530

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - coding silent

c.331G>A; p.G111R; 19:815258-815258

 lungcarcinoma; large_cell_carcinomaSubstitution - Missense

c.331G>A; p.G111R; 19:815258-815258

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.36G>A; p.K12K; 19:821524-821524

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.903C>A; p.I301I; 19:814446-814446

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - coding silent

c.639C>T; p.F213F; 19:814710-814710

 urinary_tract; bladdercarcinomaSubstitution - coding silent

c.204G>A; p.E68E; 19:815723-815723

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.573C>T; p.H191H; 19:814912-814912

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1308C>T; p.I436I; 19:813503-813503

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.823G>A; p.V275I; 19:814526-814526

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1576G>A; p.E526K; 19:813235-813235

 oesophagus; lower_thirdcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1962C>T; p.R654R; 19:812849-812849

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1175C>T; p.P392L; 19:813636-813636

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.709G>C; p.E237Q; 19:814640-814640

 breastcarcinomaSubstitution - Missense

c.1243G>A; p.D415N; 19:813568-813568

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.2135C>G; p.S712C; 19:812676-812676

 ovaryother; neoplasmSubstitution - Missense

c.567C>T; p.S189S; 19:814918-814918

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.567C>T; p.S189S; 19:814918-814918

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1824C>T; p.I608I; 19:812987-812987

 livercarcinoma; hepatocellular_carcinomaSubstitution - coding silent

c.1824C>T; p.I608I; 19:812987-812987

 livercarcinomaSubstitution - coding silent

c.616C>G; p.Q206E; 19:814733-814733

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.871G>A; p.V291M; 19:814478-814478

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.1726G>A; p.A576T; 19:813085-813085

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.640G>A; p.A214T; 19:814709-814709

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.404-5T>C; p.?; 19:815086-815086

 livercarcinoma; hepatocellular_carcinomaUnknown

c.404-5T>C; p.?; 19:815086-815086

 livercarcinoma; hepatocellular_carcinomaUnknown

c.445G>A; p.D149N; 19:815040-815040

 skin; mucosalmalignant_melanomaSubstitution - Missense

c.765G>A; p.S255S; 19:814584-814584

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.1470C>T; p.G490G; 19:813341-813341

 livercarcinomaSubstitution - coding silent

c.1470C>T; p.G490G; 19:813341-813341

 livercarcinomaSubstitution - coding silent

c.33G>A; p.P11P; 19:821527-821527

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.202G>A; p.E68K; 19:815725-815725

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.526T>C; p.S176P; 19:814959-814959

 skinmalignant_melanomaSubstitution - Missense

c.525G>T; p.T175T; 19:814960-814960

 oesophaguscarcinoma; adenocarcinomaSubstitution - coding silent

c.1591A>G; p.T531A; 19:813220-813220

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.15G>T; p.K5N; 19:821545-821545

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1591A>G; p.T531A; 19:813220-813220

 thyroidother; neoplasmSubstitution - Missense

c.583G>A; p.A195T; 19:814902-814902

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1554G>A; p.P518P; 19:813257-813257

 oesophagus; upper_thirdcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.1081G>A; p.E361K; 19:813730-813730

 livercarcinomaSubstitution - Missense

c.1081G>A; p.E361K; 19:813730-813730

 livercarcinomaSubstitution - Missense

c.1567C>G; p.H523D; 19:813244-813244

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.1441G>A; p.E481K; 19:813370-813370

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.970C>T; p.P324S; 19:813841-813841

 thyroidother; neoplasmSubstitution - Missense

c.1256G>A; p.R419H; 19:813555-813555

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.98T>A; p.I33N; 19:815829-815829

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.665C>T; p.P222L; 19:814684-814684

 skinmalignant_melanomaSubstitution - Missense

c.688G>T; p.A230S; 19:814661-814661

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.139C>T; p.P47S; 19:815788-815788

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.650_651delAT; p.Y217fs*130; 19:814698-814699

 endometriumcarcinoma; endometrioid_carcinomaDeletion - Frameshift

c.1735C>A; p.P579T; 19:813076-813076

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.611C>T; p.P204L; 19:814738-814738

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.818C>T; p.A273V; 19:814531-814531

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.127_130delGACC; p.D43fs*31; 19:815797-815800

 central_nervous_system; posterior_fossaglioma; astrocytoma_Grade_IVDeletion - Frameshift

c.1839G>A; p.A613A; 19:812972-812972

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.174T>C; p.T58T; 19:815753-815753

 livercarcinomaSubstitution - coding silent

c.348C>A; p.I116I; 19:815241-815241

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

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