| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 7486 |
Name | WRN |
Synonymous | Werner syndrome, RecQ helicase-like;WRN;Werner syndrome, RecQ helicase-like |
Definition | DNA helicase, RecQ-like type 3|Werner syndrome ATP-dependent helicase|exonuclease WRN|recQ protein-like 2 |
Position | 8p12 |
Gene Type | protein-coding |
Gene Interactions: | Physical Interaction Metabolic Interaction Signaling Interaction |
Physical Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
in same component |
TERF2 | NCI_NATURE; |
interacts with |
ATM | BIOGRID; |
interacts with |
ATM | HPRD; |
interacts with |
ATR | BIOGRID; |
interacts with |
ATRX | BIOGRID; |
interacts with |
BLM | BIOGRID; |
interacts with |
BLM | HPRD; |
interacts with |
CDKN2A | HPRD; |
interacts with |
CHAF1A | BIOGRID; |
interacts with |
DDX17 | INTACT; |
interacts with |
DHX9 | BIOGRID; |
interacts with |
EXO1 | BIOGRID; |
interacts with |
FEN1 | BIOGRID; |
interacts with |
FEN1 | HPRD; |
interacts with |
GIS1 | BIOGRID; |
interacts with |
H2AFX | BIOGRID; |
interacts with |
H2AFX | HPRD; |
interacts with |
H2AFX | MINT; |
interacts with |
MDC1 | BIOGRID; |
interacts with |
NBN | BIOGRID; |
interacts with |
NLRP2 | MINT; |
interacts with |
PARP1 | HPRD; |
interacts with |
PARP1 | INTACT; |
interacts with |
PCNA | BIOGRID; |
interacts with |
PCNA | HPRD; |
interacts with |
PCNA | MINT; |
interacts with |
POLB | BIOGRID; |
interacts with |
POLR1C | BIOGRID; |
interacts with |
PRKAR1B | HPRD; |
interacts with |
PRKDC | BIOGRID; |
interacts with |
PRKDC | HPRD; |
interacts with |
RAD51 | BIOGRID; |
interacts with |
RAD52 | BIOGRID; |
interacts with |
RAD52 | MINT; |
interacts with |
RAD54B | BIOGRID; |
interacts with |
RPA1 | HPRD; |
interacts with |
SUPT16H | INTACT; |
interacts with |
TERF2 | BIOGRID; |
interacts with |
TERF2 | HPRD; |
interacts with |
TMPO | INTACT; |
interacts with |
TOP1 | INTACT; |
interacts with |
TP53 | BIOGRID; |
interacts with |
WDR48 | BIOGRID; |
interacts with |
WRNIP1 | BIOGRID; |
interacts with |
WRNIP1 | HPRD; |
interacts with |
XRCC5 | BIOGRID; |
interacts with |
XRCC5 | HPRD; |
interacts with |
XRCC5 | INTACT; |
interacts with |
XRCC6 | BIOGRID; |
interacts with |
XRCC6 | HPRD; |
interacts with |
XRCC6 | INTACT; |
Metabolic Interaction [Top] | ||
There is no record for WRN | ||
Signaling Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
reacts with |
TERF2 | NCI_NATURE; |
reacts with |
WRN | NCI_NATURE; |