| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 4170 |
Name | MCL1 |
Synonymous | myeloid cell leukemia 1;MCL1;myeloid cell leukemia 1 |
Definition | bcl-2-like protein 3|bcl-2-related protein EAT/mcl1|induced myeloid leukemia cell differentiation protein Mcl-1|myeloid cell leukemia ES|myeloid cell leukemia sequence 1 (BCL2-related) |
Position | 1q21 |
Gene Type | protein-coding |
Gene Interactions: | Physical Interaction Metabolic Interaction Signaling Interaction |
Physical Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
in same component |
BAK1 | NCI_NATURE; |
interacts with |
ATPAF1 | MINT; |
interacts with |
BAD | BIOGRID; |
interacts with |
BAK1 | BIOGRID; |
interacts with |
BAK1 | HPRD; |
interacts with |
BAK1 | INTACT; |
interacts with |
BAK1 | MINT; |
interacts with |
BAX | BIOGRID; |
interacts with |
BAX | HPRD; |
interacts with |
BAX | INTACT; |
interacts with |
BAX | MINT; |
interacts with |
BBC3 | BIOGRID; |
interacts with |
BBC3 | HPRD; |
interacts with |
Bcl2l11 | BIOGRID; |
interacts with |
BCL2L11 | BIOGRID; |
interacts with |
BCL2L11 | HPRD; |
interacts with |
BCL2L11 | INTACT; |
interacts with |
Bcl2l11 | MINT; |
interacts with |
BCL2L11 | MINT; |
interacts with |
BCL2L1 | BIOGRID; |
interacts with |
BCL2L1 | HPRD; |
interacts with |
BCL2L1 | MINT; |
interacts with |
BCL2 | MINT; |
interacts with |
BECN1 | MINT; |
interacts with |
BID | BIOGRID; |
interacts with |
BIK | BIOGRID; |
interacts with |
BIK | HPRD; |
interacts with |
BMF | BIOGRID; |
interacts with |
BMF | HPRD; |
interacts with |
BOK | BIOGRID; |
interacts with |
BOK | HPRD; |
interacts with |
CASP3 | BIOGRID; |
interacts with |
CASP3 | HPRD; |
interacts with |
DAD1 | BIOGRID; |
interacts with |
DAD1 | HPRD; |
interacts with |
DIABLO | MINT; |
interacts with |
GSK3A | HPRD; |
interacts with |
GSK3B | HPRD; |
interacts with |
HRK | BIOGRID; |
interacts with |
HSPD1 | MINT; |
interacts with |
HUWE1 | BIOGRID; |
interacts with |
HUWE1 | HPRD; |
interacts with |
HUWE1 | INTACT; |
interacts with |
HUWE1 | MINT; |
interacts with |
MAPK10 | BIOGRID; |
interacts with |
MAPK1 | HPRD; |
interacts with |
MT-CO1 | MINT; |
interacts with |
MT-RNR2 | MINT; |
interacts with |
PCNA | BIOGRID; |
interacts with |
PCNA | HPRD; |
interacts with |
PIN1 | BIOGRID; |
interacts with |
PMAIP1 | BIOGRID; |
interacts with |
PMAIP1 | HPRD; |
interacts with |
PMAIP1 | INTACT; |
interacts with |
PMAIP1 | MINT; |
interacts with |
TNKS | BIOGRID; |
interacts with |
TNKS | HPRD; |
interacts with |
TPT1 | HPRD; |
interacts with |
VDAC1 | BIOGRID; |
interacts with |
VDAC1 | HPRD; |
Metabolic Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
metabolic catalysis |
AKT1 | NCI_NATURE; |
metabolic catalysis |
ARNT | NCI_NATURE; |
metabolic catalysis |
E2F1 | NCI_NATURE; |
metabolic catalysis |
HIF1A | NCI_NATURE; |
Signaling Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
reacts with |
BAK1 | NCI_NATURE; |
reacts with |
MCL1 | NCI_NATURE; |
reacts with |
TP53 | NCI_NATURE; |