| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 4170 |
Name | MCL1 |
Synonym | BCL2L3|EAT|MCL1-ES|MCL1L|MCL1S|Mcl-1|TM|bcl2-L-3|mcl1/EAT;myeloid cell leukemia 1;MCL1;myeloid cell leukemia 1 |
Definition | bcl-2-like protein 3|bcl-2-related protein EAT/mcl1|induced myeloid leukemia cell differentiation protein Mcl-1|myeloid cell leukemia ES|myeloid cell leukemia sequence 1 (BCL2-related) |
Position | 1q21 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | E2F transcription factor network;PID Curated;200027 |
Pathway | Apoptosis signaling pathway;PANTHER;P00006 |
Pathway | IL6-mediated signaling events;PID Curated;200124 |
Pathway | HIF-1-alpha transcription factor network;PID Curated;200172 |
Pathway | Direct p53 effectors;PID Curated;200101 |
Disease | Tuberculosis;FunDO |
Disease | Testicular dysfunction;FunDO |
Disease | Cancer;FunDO |
Disease | Rheumatoid arthritis;FunDO |
External Links | |
Links to Entrez Gene | 4170 |
Links to all GeneRIF Items | 4170 |
Links to iHOP | 4170 |
Sequence Information | |
Nucleotide Sequence | >4170 : length: 4107 GCGCAACCCTCCGGAAGCTGCCGCCCCTTTCCCCTTTTATGGGAATACTTTTTTTAAAAA AAAAGAGTTCGCTGGCGCCACCCCGTAGGACTGGCCGCCCTAAAACCGTGATAAAGGAGC TGCTCGCCACTTCTCACTTCCGCTTCCTTCCAGTAAGGAGTCGGGGTCTTCCCCAGTTTT CTCAGCCAGGCGGCGGCGGCGACTGGCAATGTTTGGCCTCAAAAGAAACGCGGTAATCGG ACTCAACCTCTACTGTGGGGGGGCCGGCTTGGGGGCCGGCAGCGGCGGCGCCACCCGCCC GGGAGGGCGACTTTTGGCTACGGAGAAGGAGGCCTCGGCCCGGCGAGAGATAGGGGGAGG GGAGGCCGGCGCGGTGATTGGCGGAAGCGCCGGCGCAAGCCCCCCGTCCACCCTCACGCC AGACTCCCGGAGGGTCGCGCGGCCGCCGCCCATTGGCGCCGAGGTCCCCGACGTCACCGC GACCCCCGCGAGGCTGCTTTTCTTCGCGCCCACCCGCCGCGCGGCGCCGCTTGAGGAGAT GGAAGCCCCGGCCGCTGACGCCATCATGTCGCCCGAAGAGGAGCTGGACGGGTACGAGCC GGAGCCTCTCGGGAAGCGGCCGGCTGTCCTGCCGCTGCTGGAGTTGGTCGGGGAATCTGG TAATAACACCAGTACGGACGGGTCACTACCCTCGACGCCGCCGCCAGCAGAGGAGGAGGA GGACGAGTTGTACCGGCAGTCGCTGGAGATTATCTCTCGGTACCTTCGGGAGCAGGCCAC CGGCGCCAAGGACACAAAGCCAATGGGCAGGTCTGGGGCCACCAGCAGGAAGGCGCTGGA GACCTTACGACGGGTTGGGGATGGCGTGCAGCGCAACCACGAGACGGCCTTCCAAGGCAT GCTTCGGAAACTGGACATCAAAAACGAAGACGATGTGAAATCGTTGTCTCGAGTGATGAT CCATGTTTTCAGCGACGGCGTAACAAACTGGGGCAGGATTGTGACTCTCATTTCTTTTGG TGCCTTTGTGGCTAAACACTTGAAGACCATAAACCAAGAAAGCTGCATCGAACCATTAGC AGAAAGTATCACAGACGTTCTCGTAAGGACAAAACGGGACTGGCTAGTTAAACAAAGAGG CTGGGATGGGTTTGTGGAGTTCTTCCATGTAGAGGACCTAGAAGGTGGCATCAGGAATGT GCTGCTGGCTTTTGCAGGTGTTGCTGGAGTAGGAGCTGGTTTGGCATATCTAATAAGATA GCCTTACTGTAAGTGCAATAGTTGACTTTTAACCAACCACCACCACCACCAAAACCAGTT TATGCAGTTGGACTCCAAGCTGTAACTTCCTAGAGTTGCACCCTAGCAACCTAGCCAGAA AAGCAAGTGGCAAGAGGATTATGGCTAACAAGAATAAATACATGGGAAGAGTGCTCCCCA TTGATTGAAGAGTCACTGTCTGAAAGAAGCAAAGTTCAGTTTCAGCAACAAACAAACTTT GTTTGGGAAGCTATGGAGGAGGACTTTTAGATTTAGTGAAGATGGTAGGGTGGAAAGACT TAATTTCCTTGTTGAGAACAGGAAAGTGGCCAGTAGCCAGGCAAGTCATAGAATTGATTA CCCGCCGAATTCATTAATTTACTGTAGTGTTAAGAGAAGCACTAAGAATGCCAGTGACCT GTGTAAAAGTTACAAGTAATAGAACTATGACTGTAAGCCTCAGTACTGTACAAGGGAAGC TTTTCCTCTCTCTAATTAGCTTTCCCAGTATACTTCTTAGAAAGTCCAAGTGTTCAGGAC TTTTATACCTGTTATACTTTGGCTTGGTTTCCATGATTCTTACTTTATTAGCCTAGTTTA TCACCAATAATACTTGACGGAAGGCTCAGTAATTAGTTATGAATATGGATATCCTCAATT CTTAAGACAGCTTGTAAATGTATTTGTAAAAATTGTATATATTTTTACAGAAAGTCTATT TCTTTGAAACGAAGGAAGTATCGAATTTACATTAGTTTTTTTCATACCCTTTTGAACTTT GCAACTTCCGTAATTAGGAACCTGTTTCTTACAGCTTTTCTATGCTAAACTTTGTTCTGT TCAGTTCTAGAGTGTATACAGAACGAATTGATGTGTAACTGTATGCAGACTGGTTGTAGT GGAACAAATCTGATAACTATGCAGGTTTAAATTTTCTTATCTGATTTTGGTAAGTATTCC TTAGATAGGTTTTTCTTTGAAAACCTGGGATTGAGAGGTTGATGAATGGAAATTCTTTCA CTTCATTATATGCAAGTTTTCAATAATTAGGTCTAAGTGGAGTTTTAAGGTTACTGATGA CTTACAAATAATGGGCTCTGATTGGGCAATACTCATTTGAGTTCCTTCCATTTGACCTAA TTTAACTGGTGAAATTTAAAGTGAATTCATGGGCTCATCTTTAAAGCTTTTACTAAAAGA TTTTCAGCTGAATGGAACTCATTAGCTGTGTGCATATAAAAAGATCACATCAGGTGGATG GAGAGACATTTGATCCCTTGTTTGCTTAATAAATTATAAAATGATGGCTTGGAAAAGCAG GCTAGTCTAACCATGGTGCTATTATTAGGCTTGCTTGTTACACACACAGGTCTAAGCCTA GTATGTCAATAAAGCAAATACTTACTGTTTTGTTTCTATTAATGATTCCCAAACCTTGTT GCAAGTTTTTGCATTGGCATCTTTGGATTTCAGTCTTGATGTTTGTTCTATCAGACTTAA CCTTTTATTTCCTGTCCTTCCTTGAAATTGCTGATTGTTCTGCTCCCTCTACAGATATTT ATATCAATTCCTACAGCTTTCCCCTGCCATCCCTGAACTCTTTCTAGCCCTTTTAGATTT TGGCACTGTGAAACCCCTGCTGGAAACCTGAGTGACCCTCCCTCCCCACCAAGAGTCCAC AGACCTTTCATCTTTCACGAACTTGATCCTGTTAGCAGGTGGTAATACCATGGGTGCTGT GACACTAACAGTCATTGAGAGGTGGGAGGAAGTCCCTTTTCCTTGGACTGGTATCTTTTC AACTATTGTTTTATCCTGTCTTTGGGGGCAATGTGTCAAAAGTCCCCTCAGGAATTTTCA GAGGAAAGAACATTTTATGAGGCTTTCTCTAAAGTTTCCTTTGTATAGGAGTATGCTCAC TTAAATTTACAGAAAGAGGTGAGCTGTGTTAAACCTCAGAGTTTAAAAGCTACTGATAAA CTGAAGAAAGTGTCTATATTGGAACTAGGGTCATTTGAAAGCTTCAGTCTCGGAACATGA CCTTTAGTCTGTGGACTCCATTTAAAAATAGGTATGAATAAGATGACTAAGAATGTAATG GGGAAGAACTGCCCTGCCTGCCCATCTCAGAGCCATAAGGTCATCTTTGCTAGAGCTATT TTTACCTATGTATTTATCGTTCTTGATCATAAGCCGCTTATTTATATCATGTATCTCTAA GGACCTAAAAGCACTTTATGTAGTTTTTAATTAATCTTAAGATCTGGTTACGGTAACTAA AAAAGCCTGTCTGCCAAATCCAGTGGAAACAAGTGCATAGATGTGAATTGGTTTTTAGGG GCCCCACTTCCCAATTCATTAGGTATGACTGTGGAAATACAGACAAGGATCTTAGTTGAT ATTTTGGGCTTGGGGCAGTGAGGGCTTAGGACACCCCAAGTGGTTTGGGAAAGGAGGAGG GGAGTGGTGGGTTTATAGGGGGAGGAGGAGGCAGGTGGTCTAAGTGCTGACTGGCTACGT AGTTCGGGCAAATCCTCCAAAAGGGAAAGGGAGGATTTGCTTAGAAGGATGGCGCTCCCA GTGACTACTTTTTGACTTCTGTTTGTCTTACGCTTCTCTCAGGGAAAAACATGCAGTCCT CTAGTGTTTCATGTACATTCTGTGGGGGGTGAACACCTTGGTTCTGGTTAAACAGCTGTA CTTTTGATAGCTGTGCCAGGAAGGGTTAGGACCAACTACAAATTAATGTTGGTTGTCAAA TGTAGTGTGTTTCCCTAACTTTCTGTTTTTCCTGAGAAAAAAAAATAAATCTTTTATTCA AATACAGGGAAAAAAAAAAAAAAAAAA |
Protein Sequence | >4170 : length: 350 MFGLKRNAVIGLNLYCGGAGLGAGSGGATRPGGRLLATEKEASARREIGGGEAGAVIGGS AGASPPSTLTPDSRRVARPPPIGAEVPDVTATPARLLFFAPTRRAAPLEEMEAPAADAIM SPEEELDGYEPEPLGKRPAVLPLLELVGESGNNTSTDGSLPSTPPPAEEEEDELYRQSLE IISRYLREQATGAKDTKPMGRSGATSRKALETLRRVGDGVQRNHETAFQGMLRKLDIKNE DDVKSLSRVMIHVFSDGVTNWGRIVTLISFGAFVAKHLKTINQESCIEPLAESITDVLVR TKRDWLVKQRGWDGFVEFFHVEDLEGGIRNVLLAFAGVAGVGAGLAYLIR |