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General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

3717

Name

JAK2

Synonymous

Janus kinase 2;JAK2;Janus kinase 2

Definition

JAK-2|Janus kinase 2 (a protein tyrosine kinase)|tyrosine-protein kinase JAK2

Position

9p24

Gene Type

protein-coding

Gene Interactions:

Physical Interaction
Metabolic Interaction
Signaling Interaction

Physical Interaction   [Top]

Interaction Type

Interactor

Data Source

in same component

 CSF2NCI_NATURE;

in same component

 CSF2REACTOME;

in same component

 CSF2RANCI_NATURE;

in same component

 CSF2RAREACTOME;

in same component

 CSF2RBNCI_NATURE;

in same component

 CSF2RBREACTOME;

in same component

 CXCL12NCI_NATURE;

in same component

 CXCR4NCI_NATURE;

in same component

 EBI3NCI_NATURE;

in same component

 EPONCI_NATURE;

in same component

 EPORNCI_NATURE;

in same component

 GAB2NCI_NATURE;

in same component

 GHRREACTOME;

in same component

 HBEGFNCI_NATURE;

in same component

 HES1NCI_NATURE;

in same component

 IFNGNCI_NATURE;

in same component

 IFNGREACTOME;

in same component

 IFNGR1NCI_NATURE;

in same component

 IFNGR1REACTOME;

in same component

 IFNGR2REACTOME;

in same component

 IL12ANCI_NATURE;

in same component

 IL12BNCI_NATURE;

in same component

 IL12RB1NCI_NATURE;

in same component

 IL12RB2NCI_NATURE;

in same component

 IL13RA1NCI_NATURE;

in same component

 IL23ANCI_NATURE;

in same component

 IL23RNCI_NATURE;

in same component

 IL27NCI_NATURE;

in same component

 IL27RANCI_NATURE;

in same component

 IL3NCI_NATURE;

in same component

 IL3REACTOME;

in same component

 IL3RANCI_NATURE;

in same component

 IL3RAREACTOME;

in same component

 IL4NCI_NATURE;

in same component

 IL4RNCI_NATURE;

in same component

 IL5NCI_NATURE;

in same component

 IL5REACTOME;

in same component

 IL5RANCI_NATURE;

in same component

 IL5RAREACTOME;

in same component

 IL6NCI_NATURE;

in same component

 IL6RNCI_NATURE;

in same component

 IL6STNCI_NATURE;

in same component

 INPP5DNCI_NATURE;

in same component

 JAK1NCI_NATURE;

in same component

 JAK1REACTOME;

in same component

 KITREACTOME;

in same component

 LEPNCI_NATURE;

in same component

 LEPRNCI_NATURE;

in same component

 LYNREACTOME;

in same component

 PIK3CANCI_NATURE;

in same component

 PIK3R1NCI_NATURE;

in same component

 PRLNCI_NATURE;

in same component

 PRLRNCI_NATURE;

in same component

 PTPN11NCI_NATURE;

in same component

 PTPN1REACTOME;

in same component

 PTPN6REACTOME;

in same component

 SHC1NCI_NATURE;

in same component

 SOCS1NCI_NATURE;

in same component

 SOCS3NCI_NATURE;

in same component

 SOS1NCI_NATURE;

in same component

 SPHK2NCI_NATURE;

in same component

 TYK2NCI_NATURE;

in same component

 YWHAZNCI_NATURE;

interacts with

 ACACAINTACT;

interacts with

 AGTR1HPRD;

interacts with

 ALKBIOGRID;

interacts with

 ANKRD11INTACT;

interacts with

 APAF1INTACT;

interacts with

 ARMC1INTACT;

interacts with

 ASXL1INTACT;

interacts with

 BAG3INTACT;

interacts with

 BAZ1BINTACT;

interacts with

 BAZ2BINTACT;

interacts with

 BDP1INTACT;

interacts with

 BRCA1BIOGRID;

interacts with

 BRCA1MINT;

interacts with

 CCR2HPRD;

interacts with

 CCR5BIOGRID;

interacts with

 CCR5HPRD;

interacts with

 CRLF2HPRD;

interacts with

 CSF2RBBIOGRID;

interacts with

 CSF2RBHPRD;

interacts with

 CSF3RHPRD;

interacts with

 CTLA4BIOGRID;

interacts with

 CTLA4HPRD;

interacts with

 CXCR4BIOGRID;

interacts with

 CXCR4HPRD;

interacts with

 DHX30INTACT;

interacts with

 DNAJA3BIOGRID;

interacts with

 DNAJA3HPRD;

interacts with

 DNMT1INTACT;

interacts with

 EGFRBIOGRID;

interacts with

 EGFRHPRD;

interacts with

 EGFRMINT;

interacts with

 ELP2BIOGRID;

interacts with

 ELP2HPRD;

interacts with

 EPORBIOGRID;

interacts with

 EPORHPRD;

interacts with

 ERBB2BIOGRID;

interacts with

 ERBB2HPRD;

interacts with

 ERBB3MINT;

interacts with

 ERBB4INTACT;

interacts with

 FANCCINTACT;

interacts with

 FESHPRD;

interacts with

 FGFR1BIOGRID;

interacts with

 FYNBIOGRID;

interacts with

 FYNHPRD;

interacts with

 G3BP1MINT;

interacts with

 GHRBIOGRID;

interacts with

 GHRHPRD;

interacts with

 GRB10BIOGRID;

interacts with

 GRB10HPRD;

interacts with

 GRHL2INTACT;

interacts with

 GTF2IHPRD;

interacts with

 HES1HPRD;

interacts with

 Hes5CELL_MAP;

interacts with

 HES5HPRD;

interacts with

 HSP90AA1BIOGRID;

interacts with

 HSP90AB1BIOGRID;

interacts with

 HSPA8BIOGRID;

interacts with

 HSPA8HPRD;

interacts with

 HTR2ABIOGRID;

interacts with

 HTR2AHPRD;

interacts with

 IFNGR1BIOGRID;

interacts with

 IFNGR1HPRD;

interacts with

 IFNGR2BIOGRID;

interacts with

 IFNGR2HPRD;

interacts with

 IGF1RHPRD;

interacts with

 IKBKGBIOGRID;

interacts with

 IL12RB2BIOGRID;

interacts with

 IL12RB2HPRD;

interacts with

 IL23RHPRD;

interacts with

 IL2RBBIOGRID;

interacts with

 IL3RAHPRD;

interacts with

 IL4RHPRD;

interacts with

 IL5RABIOGRID;

interacts with

 IL6STBIOGRID;

interacts with

 INSRBIOGRID;

interacts with

 INSRHPRD;

interacts with

 IRS1BIOGRID;

interacts with

 IRS1HPRD;

interacts with

 IRS2HPRD;

interacts with

 ITCHINTACT;

interacts with

 JAK1INTACT;

interacts with

 JAK3HPRD;

interacts with

 KAT2AINTACT;

interacts with

 KITBIOGRID;

interacts with

 KITCELL_MAP;

interacts with

 KITHPRD;

interacts with

 LATS2INTACT;

interacts with

 LEPRHPRD;

interacts with

 LMO7INTACT;

interacts with

 LYNBIOGRID;

interacts with

 LYNHPRD;

interacts with

 MAP3K1INTACT;

interacts with

 MDKHPRD;

interacts with

 MED1INTACT;

interacts with

 MLL5INTACT;

interacts with

 MPLHPRD;

interacts with

 MST1RHPRD;

interacts with

 NCK1MINT;

interacts with

 NCOR1INTACT;

interacts with

 NCOR2INTACT;

interacts with

 NFKBIAHPRD;

interacts with

 NSD1INTACT;

interacts with

 OSMRHPRD;

interacts with

 PARP1INTACT;

interacts with

 PDGFRBHPRD;

interacts with

 PHKA1INTACT;

interacts with

 PIK3CGINTACT;

interacts with

 PIK3R1BIOGRID;

interacts with

 PIK3R1HPRD;

interacts with

 PIK3R1MINT;

interacts with

 PKD1HPRD;

interacts with

 PKD1L3INTACT;

interacts with

 PLCG1MINT;

interacts with

 PLCG2HPRD;

interacts with

 PPEF2INTACT;

interacts with

 PPIABIOGRID;

interacts with

 PPIAHPRD;

interacts with

 PPP2CAHPRD;

interacts with

 PPP2R1BBIOGRID;

interacts with

 PPP2R1BHPRD;

interacts with

 PPP2R4BIOGRID;

interacts with

 PPP2R5AHPRD;

interacts with

 PRLRBIOGRID;

interacts with

 PRLRHPRD;

interacts with

 PRMT5BIOGRID;

interacts with

 PRMT5HPRD;

interacts with

 PRMT5INTACT;

interacts with

 PTAFRHPRD;

interacts with

 PTK2BBIOGRID;

interacts with

 PTK2BHPRD;

interacts with

 PTK2BIOGRID;

interacts with

 PTPN11BIOGRID;

interacts with

 PTPN11HPRD;

interacts with

 PTPN12BIOGRID;

interacts with

 PTPN12CELL_MAP;

interacts with

 PTPN12HPRD;

interacts with

 PTPN1BIOGRID;

interacts with

 PTPN1HPRD;

interacts with

 PTPN1MINT;

interacts with

 PTPN6BIOGRID;

interacts with

 PTPN6HPRD;

interacts with

 PTPRCHPRD;

interacts with

 RAF1BIOGRID;

interacts with

 RAF1HPRD;

interacts with

 RARAINTACT;

interacts with

 RSF1INTACT;

interacts with

 SETD2INTACT;

interacts with

 SH2B1BIOGRID;

interacts with

 SH2B1HPRD;

interacts with

 SH2B1MINT;

interacts with

 SH2B2BIOGRID;

interacts with

 SH2B2HPRD;

interacts with

 SH2B2MINT;

interacts with

 SHC1BIOGRID;

interacts with

 SHC1HPRD;

interacts with

 SIRPABIOGRID;

interacts with

 SIRPAHPRD;

interacts with

 SOCS1BIOGRID;

interacts with

 SOCS1HPRD;

interacts with

 SOCS1MINT;

interacts with

 SOCS3BIOGRID;

interacts with

 SOCS3HPRD;

interacts with

 SOCS3MINT;

interacts with

 STAM2BIOGRID;

interacts with

 STAM2HPRD;

interacts with

 STAMBIOGRID;

interacts with

 STAMHPRD;

interacts with

 STAP2HPRD;

interacts with

 STAT1BIOGRID;

interacts with

 STAT1CELL_MAP;

interacts with

 STAT1HPRD;

interacts with

 STAT2HPRD;

interacts with

 STAT3BIOGRID;

interacts with

 STAT3CELL_MAP;

interacts with

 STAT3HPRD;

interacts with

 STAT5ABIOGRID;

interacts with

 STAT5AHPRD;

interacts with

 STAT5BBIOGRID;

interacts with

 STAT5BHPRD;

interacts with

 TAF5LINTACT;

interacts with

 TECBIOGRID;

interacts with

 TECHPRD;

interacts with

 TNFRSF1ABIOGRID;

interacts with

 TNFRSF1AHPRD;

interacts with

 TRIP11INTACT;

interacts with

 TRPC6NCI_NATURE;

interacts with

 TSHRBIOGRID;

interacts with

 TSHRHPRD;

interacts with

 TSHZ1INTACT;

interacts with

 TUBBIOGRID;

interacts with

 TUBHPRD;

interacts with

 TYK2HPRD;

interacts with

 UBASH3BHPRD;

interacts with

 VAV1BIOGRID;

interacts with

 VAV1HPRD;

interacts with

 WDR7INTACT;

interacts with

 YES1BIOGRID;

interacts with

 YES1HPRD;

interacts with

 ZBTB40INTACT;

Metabolic Interaction   [Top]

There is no record for JAK2

Signaling Interaction   [Top]

Interaction Type

Interactor

Data Source

reacts with

 CSF2NCI_NATURE;

reacts with

 CSF2REACTOME;

reacts with

 CSF2RANCI_NATURE;

reacts with

 CSF2RAREACTOME;

reacts with

 CSF2RBNCI_NATURE;

reacts with

 CSF2RBREACTOME;

reacts with

 CXCL12NCI_NATURE;

reacts with

 CXCR4NCI_NATURE;

reacts with

 EBI3NCI_NATURE;

reacts with

 EPONCI_NATURE;

reacts with

 EPORNCI_NATURE;

reacts with

 GAB2NCI_NATURE;

reacts with

 GHRREACTOME;

reacts with

 HBEGFNCI_NATURE;

reacts with

 HES1NCI_NATURE;

reacts with

 IFNGNCI_NATURE;

reacts with

 IFNGREACTOME;

reacts with

 IFNGR1NCI_NATURE;

reacts with

 IFNGR1REACTOME;

reacts with

 IFNGR2REACTOME;

reacts with

 IL12ANCI_NATURE;

reacts with

 IL12BNCI_NATURE;

reacts with

 IL12RB1NCI_NATURE;

reacts with

 IL12RB2NCI_NATURE;

reacts with

 IL13RA1NCI_NATURE;

reacts with

 IL23ANCI_NATURE;

reacts with

 IL23RNCI_NATURE;

reacts with

 IL27NCI_NATURE;

reacts with

 IL27RANCI_NATURE;

reacts with

 IL3NCI_NATURE;

reacts with

 IL3REACTOME;

reacts with

 IL3RANCI_NATURE;

reacts with

 IL3RAREACTOME;

reacts with

 IL4NCI_NATURE;

reacts with

 IL4RNCI_NATURE;

reacts with

 IL5NCI_NATURE;

reacts with

 IL5REACTOME;

reacts with

 IL5RANCI_NATURE;

reacts with

 IL5RAREACTOME;

reacts with

 IL6NCI_NATURE;

reacts with

 IL6RNCI_NATURE;

reacts with

 IL6STNCI_NATURE;

reacts with

 INPP5DNCI_NATURE;

reacts with

 JAK1NCI_NATURE;

reacts with

 JAK1REACTOME;

reacts with

 JAK2NCI_NATURE;

reacts with

 JAK2REACTOME;

reacts with

 KITREACTOME;

reacts with

 LEPNCI_NATURE;

reacts with

 LEPRNCI_NATURE;

reacts with

 LYNREACTOME;

reacts with

 PIK3CANCI_NATURE;

reacts with

 PIK3R1NCI_NATURE;

reacts with

 PRLNCI_NATURE;

reacts with

 PRLRNCI_NATURE;

reacts with

 PTPN11NCI_NATURE;

reacts with

 PTPN1REACTOME;

reacts with

 PTPN6REACTOME;

reacts with

 SHC1NCI_NATURE;

reacts with

 SOCS1NCI_NATURE;

reacts with

 SOCS3NCI_NATURE;

reacts with

 SOS1NCI_NATURE;

reacts with

 SPHK2NCI_NATURE;

reacts with

 TYK2NCI_NATURE;

reacts with

 YWHAZNCI_NATURE;

state change

 CXCR4NCI_NATURE;

state change

 EDN1NCI_NATURE;

state change

 EDNRANCI_NATURE;

state change

 EPONCI_NATURE;

state change

 EPORNCI_NATURE;

state change

 ERBB2NCI_NATURE;

state change

 ERBB3NCI_NATURE;

state change

 GHRREACTOME;

state change

 IFNGREACTOME;

state change

 IFNGR1REACTOME;

state change

 IFNGR2REACTOME;

state change

 IL1BNCI_NATURE;

state change

 IL4NCI_NATURE;

state change

 JAK1REACTOME;

state change

 JAK2REACTOME;

state change

 KITNCI_NATURE;

state change

 KITREACTOME;

state change

 KITLGNCI_NATURE;

state change

 NOS2NCI_NATURE;

state change

 PDGFBNCI_NATURE;

state change

 PDGFRBNCI_NATURE;

state change

 PRLNCI_NATURE;

state change

 PRLRNCI_NATURE;

state change

 PTPN11NCI_NATURE;

state change

 Ptpn12CELL_MAP;

state change

 PTPN1NCI_NATURE;

state change

 PTPN1REACTOME;

state change

 PTPN6NCI_NATURE;

state change

 PTPN6REACTOME;

state change

 SH2B3NCI_NATURE;

state change

 SH3KBP1IMID;

state change

 SOCS1NCI_NATURE;

state change

 SOCS3NCI_NATURE;

state change

 SRCNCI_NATURE;

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