| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 5338 |
Name | PLD2 |
Synonymous | phospholipase D2;PLD2;phospholipase D2 |
Definition | PLD1C|choline phosphatase 2|hPLD2|phosphatidylcholine-hydrolyzing phospholipase D2 |
Position | 17p13.1 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | pld2(h) + PLCgamma1(r) <==> pld2(h):PLCgamma1(r) (binding) | Unc18A-isoform1(m) + pld2(h) <==> Unc18A-isoform1(m):pld2(h) (binding) | beta-actin(r) + pld2(h) <==> beta-actin(r):pld2(h) (binding) | alpha-actinin-2(r) + pld2(h) <==> alpha-actinin-2(r):pld2(h) (binding) | arf1(h){myr} + pld2(h) <==> arf1(h){myr}:pld2(h) (binding) | PLD2(h) --> pld2(h) (expression). | PC --pld2(h)--> PA + choline (hydrolysis) | PLD2(h) --> pld2-isoform1(h) (expression). | PLD2(h) --> pld2-isoform2(h) (expression). | PLD2(h) --> pld2-isoform3(h) (expression). |
|---|
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 243 | Phosphoserine (PKC alpha) | 15979581 | Phospho.ELM 6.0 | 252 | Phosphothreonine (PKC alpha) | 15979581 | Phospho.ELM 6.0 | 146 | Phosphoserine | 15979581 | Phospho.ELM 6.0 | 134 | Phosphoserine | 15979581 | Phospho.ELM 6.0 | 100 | Phosphothreonine | 15979581 | Phospho.ELM 6.0 | 99 | Phosphothreonine | 15979581 | Phospho.ELM 6.0 | 72 | Phosphothreonine | 15979581 | Phospho.ELM 6.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr17 |
Promoter: 4655892 - 4657892 | Agilent_014791 |
chr17 |
Promoter: 4655892 - 4657892 | GSE27584 |