| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 5338 |
Name | PLD2 |
Synonym | phospholipase D2;PLD2;phospholipase D2 |
Definition | PLD1C|choline phosphatase 2|hPLD2|phosphatidylcholine-hydrolyzing phospholipase D2 |
Position | 17p13.1 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | LPA receptor mediated events;PID Curated;200011 |
Pathway | Endocytosis;KEGG PATHWAY;hsa04144 |
Pathway | Fc gamma R-mediated phagocytosis;KEGG PATHWAY;hsa04666 |
Pathway | metabolism of anandamide an endogenous cannabinoid;PID BioCarta;100217 |
Pathway | Parkinson disease;PANTHER;P00049 |
Pathway | Angiopoietin receptor Tie2-mediated signaling;PID Curated;200066 |
Pathway | choline biosynthesis III;BioCyc;PWY-3561 |
Pathway | phospholipases;BioCyc;LIPASYN-PWY |
Pathway | Fc-epsilon receptor I signaling in mast cells;PID Curated;200003 |
Pathway | Metabolic pathways;KEGG PATHWAY;hsa01100 |
Pathway | Alpha-synuclein signaling;PID Curated;200187 |
Pathway | Glycerophospholipid metabolism;KEGG PATHWAY;hsa00564 |
Pathway | ErbB1 downstream signaling;PID Curated;200113 |
Pathway | Ether lipid metabolism;KEGG PATHWAY;hsa00565 |
Pathway | Angiogenesis;PANTHER;P00005 |
Pathway | Ras Pathway;PANTHER;P04393 |
Pathway | GnRH signaling pathway;KEGG PATHWAY;hsa04912 |
Pathway | Arf1 pathway;PID Curated;200167 |
Disease | Ewings sarcoma;FunDO |
Disease | CANCER;GAD |
Disease | Brain tumor;FunDO |
Disease | Yersinia infection;FunDO |
Disease | Colon cancer;FunDO |
Disease | Neoplasm metastasis;FunDO |
Disease | colorectal cancer;GAD |
External Links | |
Links to Entrez Gene | 5338 |
Links to all GeneRIF Items | 5338 |
Links to iHOP | 5338 |
Sequence Information | |
Nucleotide Sequence | >5338 : length: 3514 GCAGGCCCTGAGCCCCGGCCCCGCCTCGGCCGGCCCCGCCTCGGCCGGGGCGTGGGCTCC GGCTGCAGCTCCGGTCTGCTCTCTTGGCTCCGGAACCCCCGCGGGCGCTGGCTCCGTCTG CCAGGGATGACGGCGACCCCTGAGAGCCTCTTCCCCACTGGGGACGAACTGGACTCCAGC CAGCTCCAGATGGAGTCCGATGAGGTGGACACCCTGAAGGAGGGAGAGGACCCAGCCGAC CGGATGCACCCGTTTCTGGCCATCTATGAGCTTCAGTCTCTGAAAGTGCACCCCTTGGTG TTCGCACCTGGGGTCCCTGTCACAGCCCAGGTGGTGGGCACCGAAAGATATACCAGCGGA TCCAAGGTGGGAACCTGCACTCTGTATTCTGTCCGCTTGACTCACGGCGACTTTTCCTGG ACAACCAAGAAGAAATACCGTCATTTTCAGGAGCTGCATCGGGACCTCCTGAGACACAAA GTCTTGATGAGTCTGCTCCCTCTGGCTCGATTTGCCGTTGCCTATTCTCCAGCCCGAGAT GCAGGCAACAGAGAGATGCCCTCTCTACCCCGGGCAGGTCCTGAGGGCTCCACCAGACAT GCAGCCAGCAAACAGAAATACCTGGAGAATTACCTCAACCGTCTCTTGACCATGTCTTTC TATCGCAACTACCATGCCATGACAGAGTTCCTGGAAGTCAGTCAGCTGTCCTTTATCCCG GACTTGGGCCGCAAAGGACTGGAGGGGATGATCCGGAAGCGCTCAGGTGGCCACCGTGTT CCTGGCCTCACCTGCTGTGGCCGAGACCAAGTTTGTTATCGCTGGTCCAAGAGGTGGCTG GTGGTGAAGGACTCCTTCCTGCTGTACATGTGCCTCGAGACAGGTGCCATCTCATTTGTT CAGCTCTTTGACCCTGGCTTTGAGGTGCAAGTGGGGAAAAGGAGCACGGAGGCACGGCAC GGCGTGCGGATCGATACCTCCCACAGGTCCTTGATTCTCAAGTGCAGCAGCTACCGGCAG GCACGGTGGTGGGCCCAAGAGATCACTGAGCTGGCACAGGGCCCAGGCAGAGACTTCCTA CAGCTGCACCGGCATGACAGCTACGCCCCACCCCGGCCTGGGACCTTGGCCCGGTGGTTT GTGAATGGGGCAGGTTACTTTGCTGCTGTGGCAGATGCCATCCTTCGAGCTCAAGAGGAG ATTTTCATCACAGACTGGTGGTTGAGTCCTGAGGTTTACCTGAAGCGTCCGGCCCATTCA GATGACTGGAGACTGGACATTATGCTCAAGAGGAAGGCGGAGGAGGGTGTCCGTGTGTCT ATTCTGCTGTTTAAAGAAGTGGAATTGGCCTTGGGCATCAACAGTGGCTATAGCAAGAGG GCGCTGATGCTGCTGCACCCCAACATAAAGGTGATGCGTCACCCAGACCAAGTGACGTTG TGGGCCCATCATGAGAAGCTCCTGGTGGTGGACCAAGTGGTAGCATTCCTGGGGGGACTG GACCTTGCCTATGGCCGCTGGGATGACCTGCACTACCGACTGACTGACCTTGGAGACTCC TCTGAATCAGCTGCCTCCCAGCCTCCCACCCCGCGCCCAGACTCACCAGCCACCCCAGAC CTCTCTCACAACCAATTCTTCTGGCTGGGCAAGGACTACAGCAATCTTATCACCAAGGAC TGGGTGCAGCTGGACCGGCCTTTCGAAGATTTCATTGACAGGGAGACGACCCCTCGGATG CCATGGCGGGACGTTGGGGTGGTCGTCCATGGCCTACCGGCCCGGGACCTTGCCCGGCAC TTCATCCAGCGCTGGAACTTCACCAAGACCACCAAGGCCAAGTACAAGACTCCCACATAC CCCTACCTGCTTCCCAAGTCTACCAGCACGGCCAATCAGCTCCCCTTCACACTTCCAGGA GGGCAGTGCACCACCGTACAGGTCTTGCGATCAGTGGACCGCTGGTCAGCAGGGACTCTG GAGAACTCCATCCTCAATGCCTACCTGCACACCATCAGGGAGAGCCAGCACTTCCTCTAC ATTGAGAATCAGTTCTTCATTAGCTGCTCAGATGGGCGGACGGTTCTGAACAAGGTGGGC GATGAGATTGTGGACAGAATCCTGAAGGCCCACAAACAGGGGTGGTGTTACCGAGTCTAC GTGCTTTTGCCCTTACTCCCTGGCTTCGAGGGTGACATCTCCACGGGCGGTGGCAACTCC ATCCAGGCCATTCTGCACTTTACTTACAGGACCCTGTGTCGTGGGGAGTATTCAATCCTG CATCGCCTTAAAGCAGCCATGGGGACAGCATGGCGGGACTATATTTCCATCTGCGGGCTT CGTACACACGGAGAGCTGGGCGGGCACCCCGTCTCGGAGCTCATCTACATCCACAGCAAG GTGCTCATCGCAGATGACCGGACAGTCATCATTGGTTCTGCAAACATCAATGACCGGAGC TTGCTGGGGAAGCGGGACAGTGAGCTGGCCGTGCTGATCGAGGACACAGAGACGGAACCA TCCCTCATGAATGGGGCAGAGTATCAGGCGGGCAGGTTTGCCTTGAGTCTGCGGAAGCAC TGCTTCGGTGTGATTCTTGGAGCAAATACCCGGCCAGACTTGGATCTCCGAGACCCCATC TGTGATGACTTCTTCCAGTTGTGGCAAGACATGGCTGAGAGCAACGCCAATATCTATGAG CAGATCTTCCGCTGCCTGCCATCCAATGCCACGCGTTCCCTGCGGACTCTCCGGGAGTAC GTGGCCGTGGAGCCCTTGGCCACGGTCAGTCCCCCCTTGGCTCGGTCTGAGCTCACCCAG GTCCAGGGCCACCTGGTCCACTTCCCCCTCAAGTTCCTAGAGGATGAGTCTTTGCTGCCC CCGCTGGGTAGCAAGGAGGGCATGATCCCCCTAGAAGTGTGGACATAGTTGAGGCCCCCG TCAGGGAGAGGTCACCAGCTGCTGTGCCCCACCACGTCTGGCTCCCTGCCCCTTAACCCC AAGGACTGAGGGCAGTGCCCTTTGAGATCTGGGGAGGCAGGCATTCCTGAAGGGAACTAG AGGTGTTACAGAGGACCCTTACGTGAGAAATAGCTGAAAAGGGCACTCCCAACCCTGGGC TGGGGAGGAGGAGAGAGTCCCAGAGCTCATCCCCCCTGCTGCCCAGTGCAAACCACTTCT CCATGCTGCAAAGGAGAAGCACAGCTCCTGCCAGGGTGAGCAGGGTCAAGCCTCTTATTC CAGGAGAAGGGGGCTCTGCCCCAGGCCCTACTACCCATTGTTCCCTTCCTCTTCCTGCCC TTGAACCCCCTCCCTGTCCCAGGGCCCTCCCAGCCCATTGCTGCCAAGGTGGAGGGAAGG ATAAAGCCACTTCTGGCTTCAGCCCCCACCAGGGGAAGGAAGGAGGGCACATTAACTCCC TCCACCAGCCTGCTGACAGACACTAACTTTGTATCCGTTCAATAAGCATTTCATAAATAA AGGTGTAGAAAAGGTTAAAAAAAAAAAAAAAAAA |
Protein Sequence | >5338 : length: 933 MTATPESLFPTGDELDSSQLQMESDEVDTLKEGEDPADRMHPFLAIYELQSLKVHPLVFA PGVPVTAQVVGTERYTSGSKVGTCTLYSVRLTHGDFSWTTKKKYRHFQELHRDLLRHKVL MSLLPLARFAVAYSPARDAGNREMPSLPRAGPEGSTRHAASKQKYLENYLNRLLTMSFYR NYHAMTEFLEVSQLSFIPDLGRKGLEGMIRKRSGGHRVPGLTCCGRDQVCYRWSKRWLVV KDSFLLYMCLETGAISFVQLFDPGFEVQVGKRSTEARHGVRIDTSHRSLILKCSSYRQAR WWAQEITELAQGPGRDFLQLHRHDSYAPPRPGTLARWFVNGAGYFAAVADAILRAQEEIF ITDWWLSPEVYLKRPAHSDDWRLDIMLKRKAEEGVRVSILLFKEVELALGINSGYSKRAL MLLHPNIKVMRHPDQVTLWAHHEKLLVVDQVVAFLGGLDLAYGRWDDLHYRLTDLGDSSE SAASQPPTPRPDSPATPDLSHNQFFWLGKDYSNLITKDWVQLDRPFEDFIDRETTPRMPW RDVGVVVHGLPARDLARHFIQRWNFTKTTKAKYKTPTYPYLLPKSTSTANQLPFTLPGGQ CTTVQVLRSVDRWSAGTLENSILNAYLHTIRESQHFLYIENQFFISCSDGRTVLNKVGDE IVDRILKAHKQGWCYRVYVLLPLLPGFEGDISTGGGNSIQAILHFTYRTLCRGEYSILHR LKAAMGTAWRDYISICGLRTHGELGGHPVSELIYIHSKVLIADDRTVIIGSANINDRSLL GKRDSELAVLIEDTETEPSLMNGAEYQAGRFALSLRKHCFGVILGANTRPDLDLRDPICD DFFQLWQDMAESNANIYEQIFRCLPSNATRSLRTLREYVAVEPLATVSPPLARSELTQVQ GHLVHFPLKFLEDESLLPPLGSKEGMIPLEVWT |