| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 5330 |
Name | PLCB2 |
Synonymous | phospholipase C, beta 2;PLCB2;phospholipase C, beta 2 |
Definition | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2|phosphoinositide phospholipase C-beta-2 |
Position | 15q15 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | G-beta(b):G-gamma(b) + PLCbeta2(h) <==> G-beta(b):G-gamma(b):PLCbeta2(h) (binding) | G-alpha-o(b):GDP:G-beta(b):G-gamma(b) + PLCbeta2(h) <==> G-alpha-o(b):GDP:G-beta(b):G-gamma(b):PLCbeta2(h) (binding) | PLCbeta2(h) + G-beta(m) <==> PLCbeta2(h):G-beta(m) (binding) | G-alpha-q(m) --> PLCbeta2(h) (activation) | G-alpha-15(h) --> PLCbeta2(h) (activation) | G-alpha-11(m) --> PLCbeta2(h) (activation) | G-alpha-14(m) --> PLCbeta2(h) (activation) | G-beta-1(h):G-gamma-1(h) --> PLCbeta2(h) (activation) | G-beta-1(h):G-gamma-5(h) --> PLCbeta2(h) (activation) | IL-8(h):CXCR1(h):G-alpha-i2(h) --> PLCbeta2(h) (activation) | G-beta-1(r):G-gamma-2(b) --> PLCbeta2(h) (activation) | Cdc42(h):GTP --> PLCbeta2(h) (activation) | Rac1(h):GTP --> PLCbeta2(h) (activation) | G-beta-1(b):GNG1(b) --> PLCbeta2(h) (activation) | PLCB2(h) --> PLCbeta2(h) (expression). | G-beta-1(b):G-gamma-2(b) --> PLCbeta2(h) (activation) | G-beta-5(m):G-gamma-2(b) --> PLCbeta2(h) (activation) | PLCbeta2(h) + G-alpha-q(h) <==> PLCbeta2(h):G-alpha-q(h) (binding) | PLCbeta2(h) + Rac1(h):GTP <==> PLCbeta2(h):Rac1(h):GTP (binding) | PLCbeta2(h) + Rac2(h):GTP <==> PLCbeta2(h):Rac2(h):GTP (binding) | PLCbeta2(h) + Rac3(h):GTP <==> PLCbeta2(h):Rac3(h):GTP (binding) | PLCbeta2(h) + G-beta-1(h):G-gamma-2(h) <==> PLCbeta2(h):G-beta-1(h):G-gamma-2(h) (binding) | PLCB2(h) --> PLCbeta2(h) (expression). |
|---|
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 597 | Phosphoserine | 17081983 | Phospho.ELM 6.0 | 600 | Phosphotyrosine | 17081983 | Phospho.ELM 6.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
There is no record for PLCB2 | ||