Entrez Gene

Basic Information
Gene ID	5330
Name	PLCB2
Synonymous	phospholipase C, beta 2;PLCB2;phospholipase C, beta 2
Definition	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2\|phosphoinositide phospholipase C-beta-2
Position	15q15
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.3406G>A; p.A1136T; 15:40288867-40288867	skin	malignant_melanoma	Substitution - Missense
c.532C>T; p.R178C; 15:40302007-40302007	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1116C>T; p.I372I; 15:40298262-40298262	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1696+1G>T; p.?; 15:40296295-40296295	lung	carcinoma; small_cell_carcinoma	Unknown
c.3369G>A; p.A1123A; 15:40288904-40288904	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.2818G>C; p.G940R; 15:40291317-40291317	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1615G>T; p.E539*; 15:40296377-40296377	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.3456C>T; p.S1152S; 15:40288817-40288817	pancreas	carcinoma	Substitution - coding silent
c.1992G>A; p.P664P; 15:40294335-40294335	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.3199G>A; p.A1067T; 15:40290587-40290587	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1345C>T; p.P449S; 15:40296887-40296887	skin	malignant_melanoma	Substitution - Missense
c.1217C>T; p.S406L; 15:40297898-40297898	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1022C>T; p.S341L; 15:40298356-40298356	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.241C>T; p.L81F; 15:40302600-40302600	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.3496C>T; p.P1166S; 15:40288777-40288777	skin	malignant_melanoma	Substitution - Missense
c.879G>A; p.W293*; 15:40298680-40298680	large_intestine	carcinoma; adenocarcinoma	Substitution - Nonsense
c.986C>G; p.T329S; 15:40298573-40298573	autonomic_ganglia	neuroblastoma	Substitution - Missense
c.381T>C; p.A127A; 15:40302341-40302341	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1350C>A; p.S450R; 15:40296882-40296882	breast	carcinoma	Substitution - Missense
c.1137C>T; p.T379T; 15:40298241-40298241	skin	malignant_melanoma	Substitution - coding silent
c.1339C>T; p.P447S; 15:40296893-40296893	skin	malignant_melanoma	Substitution - Missense
c.1125C>T; p.G375G; 15:40298253-40298253	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.3364G>A; p.E1122K; 15:40288909-40288909	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2245G>A; p.A749T; 15:40293007-40293007	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1264G>C; p.E422Q; 15:40297580-40297580	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.3360G>A; p.Q1120Q; 15:40288913-40288913	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1980C>T; p.F660F; 15:40294347-40294347	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.904G>A; p.V302M; 15:40298655-40298655	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.662T>C; p.I221T; 15:40299149-40299149	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2776C>A; p.R926R; 15:40291359-40291359	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2586G>A; p.T862T; 15:40291865-40291865	liver	carcinoma	Substitution - coding silent
c.2776C>A; p.R926R; 15:40291359-40291359	thyroid	other; neoplasm	Substitution - coding silent
c.2776C>A; p.R926R; 15:40291359-40291359	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.109A>G; p.I37V; 15:40304054-40304054	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1733A>C; p.E578A; 15:40295249-40295249	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Missense
c.933C>G; p.H311Q; 15:40298626-40298626	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.504G>T; p.K168N; 15:40302138-40302138	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2626G>A; p.E876K; 15:40291627-40291627	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.2311A>G; p.N771D; 15:40292941-40292941	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2283G>T; p.K761N; 15:40292969-40292969	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2073G>C; p.G691G; 15:40293713-40293713	pancreas	NS	Substitution - coding silent
c.2466C>A; p.F822L; 15:40292124-40292124	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3386C>A; p.A1129D; 15:40288887-40288887	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.403A>T; p.K135*; 15:40302319-40302319	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Nonsense
c.590C>A; p.A197D; 15:40299221-40299221	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3452C>T; p.P1151L; 15:40288821-40288821	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3452C>T; p.P1151L; 15:40288821-40288821	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.212A>C; p.K71T; 15:40303307-40303307	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1593G>A; p.S531S; 15:40296528-40296528	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - coding silent
c.1415C>T; p.S472F; 15:40296817-40296817	skin	malignant_melanoma	Substitution - Missense
c.1274G>A; p.R425Q; 15:40297570-40297570	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1060C>T; p.R354C; 15:40298318-40298318	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Missense
c.1443T>C; p.A481A; 15:40296789-40296789	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.309C>T; p.S103S; 15:40302532-40302532	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.3195G>T; p.K1065N; 15:40290591-40290591	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1323+9G>T; p.?; 15:40297512-40297512	liver	carcinoma	Unknown
c.599C>T; p.P200L; 15:40299212-40299212	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1323+9G>T; p.?; 15:40297512-40297512	liver	carcinoma	Unknown
c.2908G>C; p.G970R; 15:40291146-40291146	bone; vertebrae	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.244C>T; p.R82W; 15:40302597-40302597	stomach	carcinoma; mixed_intestinal_and_diffuse_adenocarcinoma-unclassifiable	Substitution - Missense
c.1071G>A; p.E357E; 15:40298307-40298307	skin	malignant_melanoma	Substitution - coding silent
c.30C>T; p.P10P; 15:40307643-40307643	skin	malignant_melanoma	Substitution - coding silent
c.204C>T; p.R68R; 15:40303315-40303315	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.2099G>A; p.R700H; 15:40293687-40293687	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.658G>T; p.E220*; 15:40299153-40299153	large_intestine	carcinoma; adenocarcinoma	Substitution - Nonsense
c.658G>T; p.E220*; 15:40299153-40299153	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1792C>T; p.R598C; 15:40295050-40295050	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.1901C>T; p.T634M; 15:40294941-40294941	stomach	carcinoma; diffuse_adenocarcinoma	Substitution - Missense
c.1901C>T; p.T634M; 15:40294941-40294941	central_nervous_system; brain	glioma	Substitution - Missense
c.2237C>A; p.P746H; 15:40293015-40293015	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1321C>T; p.P441S; 15:40297523-40297523	skin	malignant_melanoma	Substitution - Missense
c.1840A>G; p.N614D; 15:40295002-40295002	liver	carcinoma	Substitution - Missense
c.772C>T; p.L258L; 15:40298876-40298876	skin	malignant_melanoma	Substitution - coding silent
c.496C>T; p.P166S; 15:40302146-40302146	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.2892C>T; p.S964S; 15:40291162-40291162	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.2397G>A; p.L799L; 15:40292373-40292373	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.645C>T; p.L215L; 15:40299166-40299166	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.3276G>A; p.E1092E; 15:40289350-40289350	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.3444C>T; p.T1148T; 15:40288829-40288829	skin	malignant_melanoma	Substitution - coding silent
c.2225A>T; p.K742M; 15:40293561-40293561	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Missense
c.3499G>T; p.E1167*; 15:40288774-40288774	prostate	carcinoma	Substitution - Nonsense
c.3130A>G; p.K1044E; 15:40290656-40290656	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.664G>T; p.D222Y; 15:40299147-40299147	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1695C>T; p.A565A; 15:40296297-40296297	skin	malignant_melanoma	Substitution - coding silent
c.1407C>A; p.G469G; 15:40296825-40296825	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1023G>A; p.S341S; 15:40298355-40298355	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1397A>C; p.Q466P; 15:40296835-40296835	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.372G>A; p.K124K; 15:40302469-40302469	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.149C>T; p.T50M; 15:40304014-40304014	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.2745C>A; p.R915R; 15:40291390-40291390	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.1278G>A; p.T426T; 15:40297566-40297566	skin	malignant_melanoma	Substitution - coding silent
c.1278G>A; p.T426T; 15:40297566-40297566	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1278G>A; p.T426T; 15:40297566-40297566	skin	malignant_melanoma	Substitution - coding silent
c.1982T>C; p.M661T; 15:40294345-40294345	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.3078G>A; p.A1026A; 15:40290796-40290796	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1380C>T; p.I460I; 15:40296852-40296852	skin	malignant_melanoma	Substitution - coding silent
c.2156G>A; p.R719Q; 15:40293630-40293630	breast	carcinoma	Substitution - Missense
c.1385A>G; p.N462S; 15:40296847-40296847	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2877G>A; p.L959L; 15:40291177-40291177	upper_aerodigestive_tract; larynx	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.373-1G>A; p.?; 15:40302350-40302350	skin	malignant_melanoma	Unknown
c.3272C>T; p.T1091M; 15:40289354-40289354	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1236C>T; p.D412D; 15:40297879-40297879	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1606G>T; p.A536S; 15:40296386-40296386	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_T_cell_leukaemia	Substitution - Missense
c.300G>A; p.T100T; 15:40302541-40302541	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.163-8G>A; p.?; 15:40303364-40303364	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Unknown
c.1606G>T; p.A536S; 15:40296386-40296386	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_T_cell_leukaemia	Substitution - Missense
c.589G>A; p.A197T; 15:40299222-40299222	breast	carcinoma	Substitution - Missense
c.814G>A; p.D272N; 15:40298834-40298834	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1623G>A; p.T541T; 15:40296369-40296369	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.589G>A; p.A197T; 15:40299222-40299222	breast	carcinoma; ductal_carcinoma	Substitution - Missense
c.348C>A; p.V116V; 15:40302493-40302493	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1944C>A; p.F648L; 15:40294383-40294383	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1431T>C; p.T477T; 15:40296801-40296801	thyroid	other; neoplasm	Substitution - coding silent
c.188G>A; p.S63N; 15:40303331-40303331	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2202G>A; p.K734K; 15:40293584-40293584	skin	malignant_melanoma	Substitution - coding silent
c.1957G>T; p.G653C; 15:40294370-40294370	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.2089C>T; p.R697C; 15:40293697-40293697	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.695C>T; p.A232V; 15:40298953-40298953	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.227_228CC>TT; p.P76L; 15:40303291-40303292	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.488G>A; p.G163E; 15:40302154-40302154	skin	malignant_melanoma	Substitution - Missense
c.419C>T; p.A140V; 15:40302303-40302303	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1037G>A; p.R346H; 15:40298341-40298341	central_nervous_system; brain	glioma	Substitution - Missense
c.3132G>C; p.K1044N; 15:40290654-40290654	breast	carcinoma; ductal_carcinoma	Substitution - Missense
c.2150G>A; p.R717H; 15:40293636-40293636	thyroid	carcinoma	Substitution - Missense
c.572C>T; p.P191L; 15:40301967-40301967	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.3132G>C; p.K1044N; 15:40290654-40290654	breast	carcinoma; ductal_carcinoma	Substitution - Missense
c.3316G>C; p.A1106P; 15:40289310-40289310	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.819G>T; p.K273N; 15:40298829-40298829	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.3073C>G; p.Q1025E; 15:40290801-40290801	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.879G>T; p.W293C; 15:40298680-40298680	pancreas	carcinoid-endocrine_tumour	Substitution - Missense
c.1635G>A; p.E545E; 15:40296357-40296357	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.3132G>T; p.K1044N; 15:40290654-40290654	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3338G>A; p.R1113Q; 15:40289288-40289288	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.3132G>T; p.K1044N; 15:40290654-40290654	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3161G>A; p.R1054Q; 15:40290625-40290625	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.3423G>A; p.S1141S; 15:40288850-40288850	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.2020G>A; p.D674N; 15:40294307-40294307	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1385A>C; p.N462T; 15:40296847-40296847	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1567G>A; p.E523K; 15:40296554-40296554	skin	malignant_melanoma	Substitution - Missense
c.327C>T; p.D109D; 15:40302514-40302514	liver	carcinoma	Substitution - coding silent
c.2272G>A; p.E758K; 15:40292980-40292980	skin	malignant_melanoma	Substitution - Missense
c.327C>T; p.D109D; 15:40302514-40302514	liver	carcinoma	Substitution - coding silent
c.489G>A; p.G163G; 15:40302153-40302153	skin	malignant_melanoma	Substitution - coding silent
c.2272G>A; p.E758K; 15:40292980-40292980	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1697-7T>C; p.?; 15:40295292-40295292	pancreas	carcinoma	Unknown
c.1724C>T; p.S575F; 15:40295258-40295258	NS	malignant_melanoma	Substitution - Missense
c.1697-7T>C; p.?; 15:40295292-40295292	pancreas	carcinoma	Unknown
c.3238A>T; p.I1080F; 15:40290054-40290054	central_nervous_system; brain	atypical_teratoid-rhabdoid_tumour	Substitution - Missense
c.2942G>C; p.R981P; 15:40291112-40291112	ovary	other; neoplasm	Substitution - Missense
c.1212C>T; p.I404I; 15:40297903-40297903	skin	malignant_melanoma	Substitution - coding silent
c.3131A>G; p.K1044R; 15:40290655-40290655	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3131A>G; p.K1044R; 15:40290655-40290655	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.237G>C; p.Q79H; 15:40302604-40302604	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1105G>A; p.E369K; 15:40298273-40298273	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2049C>T; p.T683T; 15:40294278-40294278	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.538C>T; p.R180W; 15:40302001-40302001	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.162+2T>G; p.?; 15:40303999-40303999	breast	carcinoma	Unknown
c.3201C>T; p.A1067A; 15:40290585-40290585	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.59G>A; p.G20E; 15:40307614-40307614	skin	malignant_melanoma	Substitution - Missense
c.3233C>T; p.S1078F; 15:40290059-40290059	skin	malignant_melanoma	Substitution - Missense
c.944C>T; p.T315M; 15:40298615-40298615	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2707C>A; p.R903R; 15:40291428-40291428	oesophagus; lower_third	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1857delG; p.M619fs*70; 15:40294985-40294985	endometrium	carcinoma; endometrioid_carcinoma	Deletion - Frameshift
c.780G>A; p.P260P; 15:40298868-40298868	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.3130A>C; p.K1044Q; 15:40290656-40290656	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.555C>G; p.L185L; 15:40301984-40301984	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.1349G>T; p.S450I; 15:40296883-40296883	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.2719A>G; p.K907E; 15:40291416-40291416	thyroid	other; neoplasm	Substitution - Missense
c.578G>A; p.G193D; 15:40301961-40301961	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.3503T>G; p.L1168R; 15:40288770-40288770	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1165G>T; p.E389*; 15:40297950-40297950	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.3340G>A; p.E1114K; 15:40289286-40289286	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3340G>A; p.E1114K; 15:40289286-40289286	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.3084G>T; p.E1028D; 15:40290790-40290790	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3134A>C; p.K1045T; 15:40290652-40290652	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.424G>T; p.A142S; 15:40302298-40302298	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.177G>A; p.L59L; 15:40303342-40303342	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.956A>T; p.N319I; 15:40298603-40298603	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.424G>A; p.A142T; 15:40302298-40302298	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2287C>A; p.L763I; 15:40292965-40292965	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1805G>A; p.R602H; 15:40295037-40295037	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.633C>A; p.F211L; 15:40299178-40299178	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.268_269CC>TT; p.P90F; 15:40302572-40302573	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.998C>T; p.A333V; 15:40298380-40298380	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1134G>C; p.M378I; 15:40298244-40298244	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.363C>T; p.N121N; 15:40302478-40302478	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.649C>G; p.P217A; 15:40299162-40299162	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.242T>C; p.L81P; 15:40302599-40302599	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.33delC; p.K12fs*2; 15:40307640-40307640	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.3115G>A; p.D1039N; 15:40290671-40290671	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1066G>A; p.V356M; 15:40298312-40298312	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1101C>T; p.D367D; 15:40298277-40298277	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.3344T>C; p.M1115T; 15:40289282-40289282	adrenal_gland; adrenal_gland	adrenal_cortical_carcinoma; functioning	Substitution - Missense
c.1199C>T; p.P400L; 15:40297916-40297916	breast	carcinoma	Substitution - Missense
c.21C>T; p.V7V; 15:40307652-40307652	skin	malignant_melanoma	Substitution - coding silent
c.2570G>A; p.G857E; 15:40291881-40291881	central_nervous_system; brain	glioma	Substitution - Missense
c.1213C>T; p.L405L; 15:40297902-40297902	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.506A>C; p.N169T; 15:40302136-40302136	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1075G>T; p.D359Y; 15:40298303-40298303	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.1075G>T; p.D359Y; 15:40298303-40298303	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.591C>T; p.A197A; 15:40299220-40299220	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.591C>T; p.A197A; 15:40299220-40299220	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.768C>T; p.S256S; 15:40298880-40298880	skin	malignant_melanoma	Substitution - coding silent
c.1009T>A; p.S337T; 15:40298369-40298369	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.768C>T; p.S256S; 15:40298880-40298880	skin	malignant_melanoma	Substitution - coding silent
c.3267G>A; p.Q1089Q; 15:40290025-40290025	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.299C>T; p.T100M; 15:40302542-40302542	lung	carcinoma; adenocarcinoma	Substitution - Missense

COSMIC somatic mutation [Top]