| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 4261 |
Name | CIITA |
Synonymous | class II, major histocompatibility complex, transactivator;CIITA;class II, major histocompatibility complex, transactivator |
Definition | MHC class II transactivator|MHC class II transactivator type III|NLR family, acid domain containing|nucleotide-binding oligomerization domain, leucine rich repeat and acid domain containing |
Position | 16p13 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | C2TA(h) + TAF(II)31(h) <==> C2TA(h):TAF(II)31(h) (binding) | C2TA(h) + TFIIB(h) <==> C2TA(h):TFIIB(h) (binding) | C2TA(h) + TAF(II)70-alpha(h) <==> C2TA(h):TAF(II)70-alpha(h) (binding) | C2TA(h) + RFX5(h) <==> C2TA(h):RFX5(h) (binding) | C2TA(h) + RFXANK(h) <==> C2TA(h):RFXANK(h) (binding) | C2TA(h) + NF-YB(h) <==> C2TA(h):NF-YB(h) (binding) | C2TA(h) + NF-YC-3(h) <==> C2TA(h):NF-YC-3(h) (binding) | C2TA(h) --> NF-Y(h) (binding) | C2TA(h) --> basal complex(h) (binding) | C2TA(h) --> HLA-F(h) (DNA binding) | C2TA(h) --> HLA-DRA(h) (DNA binding). | PPARgamma(h) + C2TA(h) <==> PPARgamma(h):C2TA(h) (binding) | CIITA(h) --> C2TA(h) (expression). | C2TA(h) --> HLA-DRA(h) (transactivation) | HDAC1(m.s.) + C2TA(h) <==> HDAC1(m.s.):C2TA(h) (binding) | hdac2(m.s.) + C2TA(h) <==> hdac2(m.s.):C2TA(h) (binding) | C2TA(h) + HDAC1(h) <==> C2TA(h):HDAC1(h) (binding) | C2TA(h) + NF-YB(r) <==> C2TA(h):NF-YB(r) (binding) | C2TA(h) + RFX5(h) <==> C2TA(h):RFX5(h) (binding) | CIITA(h) --> C2TA(h) (expression). |
|---|
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr16 |
Promoter: 10877058 - 10879058 | GSE27584 |
chr16 |
Promoter: 10877058 - 10879058 | PMID:15467734 |
chr16 |
Promoter: 10877058 - 10879058 | PMID:14970863 |