Cancer metastasis gene database Home
Cancer metastasis database
General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

4261

Name

CIITA

Synonymous

class II, major histocompatibility complex, transactivator;CIITA;class II, major histocompatibility complex, transactivator

Definition

MHC class II transactivator|MHC class II transactivator type III|NLR family, acid domain containing|nucleotide-binding oligomerization domain, leucine rich repeat and acid domain containing

Position

16p13

Gene Type

protein-coding

Gene Regulation:

Transcription Factors
Post Translational Modification From dbPTM
Methylation Profile From DiseaseMeth database

Transcription Factors   [Top]

Regulation From TransFac database

C2TA(h) + TAF(II)31(h) <==> C2TA(h):TAF(II)31(h) (binding)
C2TA(h) + TFIIB(h) <==> C2TA(h):TFIIB(h) (binding)
C2TA(h) + TAF(II)70-alpha(h) <==> C2TA(h):TAF(II)70-alpha(h) (binding)
C2TA(h) + RFX5(h) <==> C2TA(h):RFX5(h) (binding)
C2TA(h) + RFXANK(h) <==> C2TA(h):RFXANK(h) (binding)
C2TA(h) + NF-YB(h) <==> C2TA(h):NF-YB(h) (binding)
C2TA(h) + NF-YC-3(h) <==> C2TA(h):NF-YC-3(h) (binding)
C2TA(h) --> NF-Y(h) (binding)
C2TA(h) --> basal complex(h) (binding)
C2TA(h) --> HLA-F(h) (DNA binding)
C2TA(h) --> HLA-DRA(h) (DNA binding).
PPARgamma(h) + C2TA(h) <==> PPARgamma(h):C2TA(h) (binding)
CIITA(h) --> C2TA(h) (expression).
C2TA(h) --> HLA-DRA(h) (transactivation)
HDAC1(m.s.) + C2TA(h) <==> HDAC1(m.s.):C2TA(h) (binding)
hdac2(m.s.) + C2TA(h) <==> hdac2(m.s.):C2TA(h) (binding)
C2TA(h) + HDAC1(h) <==> C2TA(h):HDAC1(h) (binding)
C2TA(h) + NF-YB(r) <==> C2TA(h):NF-YB(r) (binding)
C2TA(h) + RFX5(h) <==> C2TA(h):RFX5(h) (binding)
CIITA(h) --> C2TA(h) (expression).

Post Translational Modification   [Top]

Location (AA)

PTM type

Literature

Database

Methylation Profile   [Top]

Chromosome

Location

Source

chr16

Promoter: 10877058 - 10879058GSE27584

chr16

Promoter: 10877058 - 10879058PMID:15467734

chr16

Promoter: 10877058 - 10879058PMID:14970863