Entrez Gene

Basic Information
Gene ID	4261
Name	CIITA
Synonymous	class II, major histocompatibility complex, transactivator;CIITA;class II, major histocompatibility complex, transactivator
Definition	MHC class II transactivator\|MHC class II transactivator type III\|NLR family, acid domain containing\|nucleotide-binding oligomerization domain, leucine rich repeat and acid domain containing
Position	16p13
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.295G>A; p.A99T; 16:10895764-10895764	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.2001G>C; p.L667L; 16:10907493-10907493	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.1801C>A; p.R601R; 16:10907293-10907293	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2072C>A; p.A691D; 16:10907564-10907564	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.265G>T; p.E89*; 16:10895734-10895734	skin; face	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.3124C>T; p.L1042F; 16:10918501-10918501	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.3171C>T; p.C1057C; 16:10922188-10922188	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.2046C>T; p.S682S; 16:10907538-10907538	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.133C>G; p.L45V; 16:10895362-10895362	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2515C>T; p.R839C; 16:10908007-10908007	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.2863C>T; p.R955W; 16:10910234-10910234	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.888C>A; p.D296E; 16:10903846-10903846	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense

COSMIC somatic mutation [Top]